After a description of the combined teaching-oriented and learning-oriented teaching model of medical information retrieval course, the results it achieved were investigated with questionnaires and its advantages were summarized from the aspects of national conditions, information literacy training and medical education.

Objective To design the meta-data scheme for medical records database of traditional Chinese medi-cine.Methods The meta-data scheme for medical records database of traditional Chinese medicine was designed u-sing the MARC meta-data according to the analysis of resources, investigation of literature, networks and users. Results The meta-data scheme for medical records database of traditional Chinese medicine is consisted of 17 fields and 9 parts.Conclusion MARC, as the mata-data criteria, can organize and describe the medical records of tradi-tional Chinese medicine.However, the standards for selection and description of meta-data criteria need to be fur-ther studied.

Objective To explore the effect of intracoronary injection of epinephrine and Vera Pammy in patients with myocardial infarction with slow blood flowduring percutaneous coronary intervention (PCI).MethodsFrom January 2013 to October 2016, 68 patients with acute myocardial infarction with solw blood flow in Shanghai Jiading Hospital of Traditional Chinese Medicine during PCI were randomly divided into the epinephrine group(37 cases) and the verapamil group(31 cases).The two groups were treated with conventional drugs before surgery.The epinephrine group were injected into the coronary artery of 50 micrograms of epinephrine, the Vera Pammy group were injected into 200 micrograms of Vera Pammy.The coronary angiography, blood flow dynamics, as well as biochemical indexes in the two groups were observed.ResultsAfter the initial medicine, the ratio of TIMI flow grade 3 in the epinephrine group 81.80% was significantly higher than that in the Vera Pammy group 64.52%(P<0.05).The ratio of TIMI flow grade 3 after three times treatment, CTFC value after initial and 3 times treatment between the two groups have no significance.The blood pressure in the epinephrine group was (82.67±10.87) mmHg, which was significantly higher than that in the Vera Pammy group (70.46±9.54) mmHg(P<0.05).NT-proBNP, cTnT, LVEF in the two groups have no significance.hs-CRP in the epinephrine group was (7.68± 0.76) mg/L, which was significantly lower than that in the Vera Pammy group (9.25±1.05) mg/L.ConclusionThe effect is different which epinephrine and Vera Pammy were used in the patients with myocardial infarction with slow blood flowduring percutaneous coronary intervention.The use of epinephrine can significantly increase blood pressure, and the effect of initial medication is better.

Erectile dysfunction (ED) results from the interaction of many pathological factors. Studies show that a high incidence of ED is associated with chronic diseases of various systems, and its pathogenesis is not fully understood. This article outlines the progress in recent studies on the impact of chronic diseases on erectile function.
Chronic Disease ; Erectile Dysfunction ; etiology ; Humans ; Male ; Penile Erection ; physiology

The RNA dot hybridization with human IL-6 cDNA showed that panaxatriol saponin (PTS) enhanced the interleukine-6(IL-6) mRNA concentration within PHA activated peripheral blood mononuclear cell (PBMC) byabout 4 folds,suggesting that PTS could promote the IL-6 gene transcription of lymphoid tissue

To study the procedure in cutting intracranial minimal lesions, intracranial minimal lesions were removed in 9 cases (male 6, female 3.) through keyhole in the guidance of frameless stereotaxy with robot. Robot image navigation orientation system was used to provide 3D images, and then these markers were made sure the coordinates of lesion target to guide the operating approach, locating anatomical structures,size of lesion and lesions to be removed in all the patients. Cases included 2 meningiomas, 2 brain abscess, 1 cyst of cysticercosis, 1 angiocavernoma, 1 metastasis tumors, 1 granuloma and 1 foreign body of metal from Mar 1, 2001 to June 1, 2001. The robot frameless stereotaxy provided accuracy of the intracranial lesions and anatomy. The postoperative neurofunction defects were not found. The outcome of operation was very good. The robot navigation system provided surgical navigational function: localization, orientation and guidance of the cutting intracranial minimal lesions in exact. It is useful in minimally invasive neurosurgery and is a good therapeutic method.

Objective To determine the effects of organic extracts of drinking water on female mice reproductive system.Methods The Kunming female mice were randomly divided into4groups,one as reagent control group,the other three as treated groups,15female mice per group.The treated groups were treated with the organics extracted from the chlorinated drinking water by the solid phase extraction at the doses of12.5,25and50L/kg respectively,once a day,continuously for5d.The pathological changes of ovary were observed by optical microscopy.Results At the10th day after treatment,the number of intermediate follicles andⅡatretic follicles in ovary in the treated group significantly increased,especially the number ofⅡa-tretic follicles in25L/kg group,which was10times as high as that in the control group.At the30th day after treatment,the number of normal follicles revealed no significant changes,the number ofⅡatretic follicles in the25and50L/kg group was still significantly higher than that in the control group,the number of corpora lutea in ovary significantly decreased with the in-creases of doses.The estrous cycle delayed at the level of50L/kg.Conclusion The organic extracts from drinking water had adverse effects on the female reproductive system by affecting the development and maturity of the follicles.

In type 2 diabetes mellitus,the levels of leptin were higher in female and obese subjects compared with male and non-obese subjects.There was negative relationship in female between leptin and HbA_1c,and negative relationship between leptin and HDL-C in male.Gender and obesity had no effect on TNF-? and NP Y.

Human IL-6,IL-10,IL-13 and SCF cDNAs encoding extra - cellular domain were isolated by reverse transcription polymerase reaction (RT-PCR). These cDNA fragments were inserted into expression vector PBV220 which contains PRP_(L), promoters and SD sequence. Then the E. coli DH5? were tronsformed with the recombinant plasmids. After screening, the clones carrying those recombinant plasmids were identified. SDS-PAEG and biological assay indicated that human IL-6, IL-10 and IL-13 were expressed in E.coli. The expression level of rhIL-6 was as high as 30% of the total bacterial protein.

Optimization of Traditional Chinese Medicine (TCM) clinical trials as philosophy, process and method, is extremely necessary and can be applied in different levels. Optimization of TCM clinical trials should follow some principles and procedures, and be executed in two ways. Optimization of treatment plan should be supported by the research basis and literature experience, and be perfected by research group and experts argumentation. Optimization of design plan is modified and accomplished by expert discussion and repeated consulting multi-disciplinary experts. Specific research objective, exact target population definition, proper design plan selection, valid calculation of sample size, precise and appropriate main outcome measures, data management system, medical ethics and statistical analysis are the focuses.