1.STUDY ON THE RELATIONSHIP BETWEEN CANCER AND TYPE I HYPERSENSITIVITY:TOTAL SERUM IgE LEVEL IN MALIGNANT LYMPHOMA
Chinese Journal of Immunology 1985;0(03):-
With conventional double-antibody sandwich technique,total IgE level in35 serum samples from malignant lymphoma patients and 35 matched normalcontrols was measured by ELISA.It was found that there was a statisticallyhigher total IgE levels in patients than in the control(p
2.One case of seminal fluid induced anaphylaxis.
Chinese Medical Journal 2013;126(11):2198-2198
Adult
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Anaphylaxis
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etiology
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Female
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Humans
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Male
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Semen
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immunology
3.Recent advances in pericytes angiogenic signaling pathways.
Wen-bao LU ; Xiao-rui SHI ; Rui-juan XIU
Chinese Journal of Pathology 2011;40(6):423-426
Angiopoietins
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metabolism
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physiology
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Animals
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Cell Proliferation
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Endothelial Cells
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cytology
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physiology
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Humans
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Neoplasms
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blood supply
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Neovascularization, Pathologic
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physiopathology
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Neovascularization, Physiologic
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physiology
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Pericytes
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cytology
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metabolism
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physiology
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Proto-Oncogene Proteins c-sis
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metabolism
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physiology
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Receptor, Platelet-Derived Growth Factor beta
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metabolism
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physiology
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Receptor, TIE-2
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metabolism
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physiology
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Signal Transduction
4.Guide and prediction value of partial pressure of end-tidal carbon dioxide during cardiopulmonary resuscitation
Rui SHI ; Rui WANG ; Jun WANG ; Yu CHEN ; Shumei GUO
Chinese Journal of Emergency Medicine 2011;20(10):1075-1078
Objective To study the clinical significance of end-tidal carbon dioxide partial pressure (PetCO2 ) during cardiopulmonary resuscitation (CPR) and seek the fixed value according which to decide if we should and when to give up.Methods This was a prospective,observational study.A total of 124 patients with cardiac arrest in or out-of-hospital from may 2003 to March 2009 in emergency department of our hospital were selected.All of them had definite etiological factors.Changes of PetCO2 in 124 cardiac arrest patients during CPR were tracked.Results The gender,age,rescue time in seventy-one patients with the return of spontaneous circulation (ROSC) after endotracheal intubation have a significant difference with that in fifty-three patients without ROSC (P <0.01 ).The PetCO2 of the survival were higher than that of patients without ROSC or with ROSC,but finally died (P <0.01 ).A fixed point 14.4 mmHg of PetCO2 after 20 minutes' CPR can be used as a reference value to guide CPR or predict prognosis.Conclusions Monitoring PetCO2 during CPR has a predictive value on the success of resuscitation.
5.A study of the related factors about acute stress responses of the military freshmen
Huang PENG ; Shi RUI ; Zhu XIA
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(9):846-848
Objective To explore the related factors about acute stress responses of the military freshmen,then built a path model among self-efficacy,social support,coping style,state-trait anxiety and acute stress responses.Methods 584 students were tested by General Self-efficacy Scale (GSES),Perceived Social Support Scale (PSSS),Coping Styles Questionnaire,State-Trait Anxiety Inventory (STAI) and Acute Stress Response Scale ( ASP S).Results ①The military freshmen in each factor of acute stress response got a lower score,especially the mean score of the changes of cognition was higher (0.21 ±0.21 ),compared with the other factors,and the changes of pathology (0.053 ±0.114) was lower.②There were significant correlations between self-efficacy,social support,positive coping,negative coping,state anxiety,trait anxiety and acute stress responses (P < 0.01 ).③ Negative coping( r=0.130),trait anxiety(r=0.005) and state anxiety(r=0.002) influenced ASR directly,meanwhile,self-efficacy( r =-1.292) influenced ASR through the state anxiety indirectly,self-efficacy ( r=-7.465 ) and social support ( r =-0.294) influenced ASR indirectly through trait anxiety.Conclusion Acute stress responses of the military freshmen were directly influenced by negative coping and state-trait anxiety,and negative coping style was the main reason.
6.Gene Mutation Screening of Melanocortin 4 Receptor of Simple Obese Children in Nanjing City
shi, XING ; qin, RUI ; han, BEI
Journal of Applied Clinical Pediatrics 2004;0(07):-
Objective To screen melanocortin 4 receptor (Mc4R) gene mutation by direct DNA sequencing in order to explore the mutation situation of Mc4R gene in simple obese children in Nanjing.Methods One hundred and five simple obese children(obesity group) and 127 healthy children(healthy control group) were examined for mutations of Mc4R gene.Body mass index(BMI)cutoff points for overweight and obesity adopted Chinese children and adolescents,recommended by China Working Group of Obesity,and all children had no other hereditary and metabolic abnormality.Touch-down PCR was performed to amplify the full length Mc4R gene,then direct DNA sequencing was used to analyze the Mc4R gene.The differences of biochemical index levels between obesity group and healthy control group were analyzed ,including alanine transaminase,aspartate transaminas,total protein,albumin,globulin,albumin/globulin,triglyceride,cholesterol,high density lipoprotein,cortisol,insulin and C peptide.Results There were significant differences of biochemical index levels between obesity group and healthy control group,including triglyceride,insulin level after dining 2 h,C peptide and BMI(Pa
7.Effects of mindfulness - based stress reduction on compliance in primary open angle glaucoma patients with topical medication
Le, YANG ; Rui, SHI ; Li-Na, JIA
International Eye Science 2017;17(10):1936-1938
AIM: To explore the effects of mindfulness- based stress reduction ( MBSR ) on anxiety, compliance and visual function in primary open angle glaucoma( POAG) patients. ·METHODS:Totally 64 patients, who were treated with topical medication and were diagnosed with POAG in the department of ophthalmology at Shaanxi Provincial People's Hospital, were randomly divided into the intervention group ( n=32 ) and the control group ( n=32 ) . Both groups received conventional mental health education while the intervention group was complemented with MBSR intervention. The patient's anxiety status, compliance rates and MD before and after the intervention were evaluated. ·RESULTS:After the MBSR intervention, the scores of HAMA of the intervention group were significantly lower than that of the control group (P<0. 01). The compliance of patients in intervention group was higher than that of the control group (P<0. 01). ·CONCLUSION:The MBSR intervention can effectively relieve the anxiety of patients and improve the compliance in primary open angle glaucoma patients. It can be promoted and put into clinical application.
8.Efficacy of intravitreal injection with Ranibizumab combined with laser photocoagulation for macular edema secondary to macular branch retinal vein occlusion
Le, YANG ; Yu-Shun, XUE ; Rui, SHI
International Eye Science 2016;16(11):2085-2087
AIM: To observe the efficacy of intravitreal injection with ranibizumab combined with laser photocoagulation for macular edema ( ME ) secondary to macular branch retinal vein occlusion( MBRVO) .
METHODS:A retrospective analysis included 33 patients (33 eyes) with ME secondary to MBRVO were taken. All patients received intravitreal injection of 0. 5mg ranibizumab ( 0. 05ml ) at first visit. The continue PRN treatment and laser photocoagulation were based on the visual acuity changes and optical coherence tomography findings. The changes of best corrected visual acuity ( BCVA) , central macular thickness( CMT) , and amplitude density and latency of P1 wave in mfERG were observed before treatment and 6mo after treatment.
RESULTS: Before the treatment, logMAR was 0. 68±0.35, 6mo after treatment was 0. 34±0. 23, BCVA was improved obviously ( P < 0. 01 ), BCVA in 21 patients ( 63.64%) were improved in two rows among all the patients. CMT before treatment was(487. 30±63. 58) μm, after treatment was(238. 84±52. 66) μm(P<0. 01). The amplitude densities of P1 wave in ring 1, ring 2 and ring 3 after treatment were significantly increased(all P<0. 01), and the latencies were decrease ( all P < 0. 05 ). The conjunctival hemorrhage was observed in 2 eyes after treatment.
CONCLUSION: Intravitreal injection with ranibizumab combined with laser photocoagulation for ME secondary to MBRVO can reduce the CMT and improve visual function.
9.Correlation between polymorphism of regulated upon activation normal T-cell expressed and secreted gene promoter and diabetic nephropathy in type 2 diabetes mellitus
Song ZHANG ; Rui WANG ; Lixin SHI
Chinese Journal of Tissue Engineering Research 2007;11(17):3447-3450
BACKGROUND: Hereditary susceptibility is an important role in episode and development of diabetic nephropathy (DN). Aggregation of monocyte in kidney tissue, differentiation to histocyte and reinforcement of signal are possibly closed to episode and development of DN in type 2 diabetes mellitus (DM). Regulated upon activation normal T-cell expressed and secreted (RANTES) is a chemokine of C-C subtribe. It can mediate infiltration and activation of inflammatory cells and cause injuries of renal corpuscle and renal mesenchymal. This may be a key mechanism of episode and development of DM. Thus, RANTES gene may be one of the susceptible gene of DN. OBJECTIVE :To investigate correlation between RANTES gene promoter -28C/G polymorphism and DN in type 2 DM in Chinese. DESIGN: Case-contrast study. SETTING: Department of Endocrine, Affiliated Hospital of Guiyang Medical College; Center of Diabetes Mellitus of Guizhou Province. PARTICIPANTS: A total of 143 patients with type 2 DM were recruited from the Department of Endocrine, Affiliated Hospital of Guiyang Medical College and Department of Endocrine,Guizhou People's Hospital from September 2003 to September 2005. Among them, 53 cases had normoalbuminuria, 54 microalbuminuria and 36 macroalbuminuria. Another 55 healthy subjects who were selected from Center of Health Examination, Affiliated Hospital of Guiyang Medical College were regarded as control group. METHODS: 3-5 mL peripheral venous blood was collected from all subjects. RANTES gene promoter -28C/G genotype was detected with polymerase chain reaction restriction fragment length polymorphism technique. MAIN OUTCOME MEASURES: ① Allele frequency and genotypic frequency of RANTES gene promoter -28C/G; ② risk factor of DN was analyzed with Logistic regression analysis. RESULTS: All 198 subjects were involved in the final analysis. ① Comparison of CG genotypic frequency of -28C/G: There was no significant difference between normal control group and DM group (P> 0.05); however, that in microalbuminuria group and macroalbuminuria group was higher than that in normoalbuminuria group (24.1%, 47.2%, 9.4%, P < 0.05), and that in macroalbuminuria group was also higher than that in microalbuminuria group (P < 0.05). ② Frequency of G allele of -28C/G: There was no significant difference between normal control group and DM group (P > 0.05); however, that in micro albuminuria group and macrealbuminuria group was higher than that in microalbuminuria group (12.0%, 23.6%, 4.7%, P < 0.05), and that in macroalbuminuria group was also higher than that in microalbuminuria group (P< 0.05). ③ Logistic regression analysis showed that positive genotype of -28G was related to DN (95% Cl:1.402-15.032, P =0.012). CONCLUSION: Positive genotype of RANTES gene promoter-28G may be related to DN.
10.Cytophagic histiocytic panniculitis.
Jie SHI ; Hong-rui LIU ; Kai FANG
Chinese Journal of Pathology 2005;34(1):59-60
Adult
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Antineoplastic Combined Chemotherapy Protocols
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administration & dosage
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therapeutic use
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Cyclophosphamide
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administration & dosage
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Diagnosis, Differential
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Female
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Humans
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Panniculitis
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drug therapy
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pathology
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Panniculitis, Nodular Nonsuppurative
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pathology
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Prednisone
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administration & dosage
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Vincristine
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administration & dosage