Reversible splenial lesion syndrome can be caused by viral infection. Rubella generally occurs in childhood, and it is rarely accompanied by neurological complications in adulthood. A 35-year-old man visited our hospital due to conjunctival injection, mild fever, and headache 3 days after experiencing skin rash. Brain magnetic resonance imaging (MRI) revealed distinct lesions involving white matter in the splenium of the corpus callosum approximately 3 days following the onset of symptoms. Enzyme immunoassay performed on serum and CSF samples was positive for rubella virus IgM. A follow-up brain MRI was performed 24 days after the onset of symptoms, and reduced lesion size with decreased signals were observed on diffusion weighted image. This case showed that rubella infection can result in reversible splenial lesion accompanied by only mild neurological symptoms.
Rubella

No abstract available.
Pregnancy ; Rubella

Studying the harmful effects of Rubella infection in pregnant women. Adults and children were infected rubella virus through upper respiratory tract. In pregnant women, virus in blood stream go through placenta and infected in some cells of fetus, caused congenital defects such as deafness (58%), ocular abnormalities (13%), heart defects (13%). Definite diagnosis based on paraclinical tests because of clinical symptoms weren’t valuable. Isolation of rubella virus in throat mucus, urine, and others were not frequent, this test commonly carried out in suspected congenital rubella syndrome. Serological diagnosis was used most commonly: IgG (+) indicating there was an immune response with rubella. It’s very important to define exactly new infected pregnancy, based on the increase of IgG titer or the presence of specific serum IgM in only serum sample. The best prevention measure is vaccination before pregnancy
Rubella ; Pregnancy

No abstract available.
Rubella* ; Vaccination*

No abstract available.
Glycoproteins* ; Oligodendroglia* ; Rubella virus* ; Rubella*

No abstract available.
Diploidy* ; Humans* ; Measles* ; Mumps* ; Rubella Vaccine* ; Rubella*

No abstract available.
Antibodies* ; Korea* ; Prevalence* ; Rubella*

An outbreak of rubella occurred from 2nd March to 4th April, 2001, in three districts: Cau Giay, Tu Liem, Dong da of Ha Noi. There were 62 rubella cases aged from 1 to 25 years. Most of the cases were observed in age group 5-9 years (80,6%). The typical symptoms were fever (100%), rash (87,1%), itching (56,4%), coryza (35,5%). Serum samples from 9 cases were tested by MAC-ELISA, and all were positive.
Rubella ; Disease Outbreaks

Background: Infants with congenital rubella syndrome (CRS) often require multiple diagnostic procedures and interventions that include cataract surgery and procedures for congenital heart abnormalities. CRS is a vaccine preventable disease. Objective: This study aimed to determine the costs incurred by the parents, Philippine Health Insurance Corporation (PHIC), hospital's medical social service (MSS), and non-governmental organization (NGO) in the management of CRS. Methods: This is a costing study of five children diagnosed with probable CRS who were managed in a tertiary government hospital in Northern Luzon, Philippines. The parents or guardians of the patients were interviewed on the cost incurred particularly on non-medical related expenses during their outpatient department consultations and admissions. Hospital bills from our institutions and those from the previous institutions, if available, were retrieved. Expenses incurred from procedures or medical supplies relating to known complications of CRS were included in the computation. Results: All five patients diagnosed with CRS had cardiac, ear, and eye manifestations. Two patients had postnatal complications. The average cost spent by the five patients' early years of life (mean age of patients was 16 ± 14 months) was ₱409,740.84. A quarter of the cost was out-of-pocket expenses while a third was covered by the hospital's MSS where the patients were seen. Another third was shouldered by an NGO. Most expenses were from the treatment of cardiac complications at 42% of the cost and had the highest average cost at ₱116,586.59. Case 1 had the highest financial cost at ₱833,514.24 mainly from the cardiac complications of CRS. Conclusion The cost of CRS in the early years of life is high. This is a significant financial burden to parents, PHIC, hospital's MSS, and NGO.
Congenital rubella syndrome ; cataract

No abstract available.
Prognosis* ; Rubella* ; Syphilis, Congenital*