Reversible splenial lesion syndrome can be caused by viral infection. Rubella generally occurs in childhood, and it is rarely accompanied by neurological complications in adulthood. A 35-year-old man visited our hospital due to conjunctival injection, mild fever, and headache 3 days after experiencing skin rash. Brain magnetic resonance imaging (MRI) revealed distinct lesions involving white matter in the splenium of the corpus callosum approximately 3 days following the onset of symptoms. Enzyme immunoassay performed on serum and CSF samples was positive for rubella virus IgM. A follow-up brain MRI was performed 24 days after the onset of symptoms, and reduced lesion size with decreased signals were observed on diffusion weighted image. This case showed that rubella infection can result in reversible splenial lesion accompanied by only mild neurological symptoms.
Rubella

Studying the harmful effects of Rubella infection in pregnant women. Adults and children were infected rubella virus through upper respiratory tract. In pregnant women, virus in blood stream go through placenta and infected in some cells of fetus, caused congenital defects such as deafness (58%), ocular abnormalities (13%), heart defects (13%). Definite diagnosis based on paraclinical tests because of clinical symptoms weren’t valuable. Isolation of rubella virus in throat mucus, urine, and others were not frequent, this test commonly carried out in suspected congenital rubella syndrome. Serological diagnosis was used most commonly: IgG (+) indicating there was an immune response with rubella. It’s very important to define exactly new infected pregnancy, based on the increase of IgG titer or the presence of specific serum IgM in only serum sample. The best prevention measure is vaccination before pregnancy
Rubella ; Pregnancy

No abstract available.
Pregnancy ; Rubella

No abstract available.
Rubella* ; Vaccination*

No abstract available.
Glycoproteins* ; Oligodendroglia* ; Rubella virus* ; Rubella*

No abstract available.
Diploidy* ; Humans* ; Measles* ; Mumps* ; Rubella Vaccine* ; Rubella*

No abstract available.
Antibodies* ; Korea* ; Prevalence* ; Rubella*

No abstract available.
Prognosis* ; Rubella* ; Syphilis, Congenital*

An outbreak of rubella occurred from 2nd March to 4th April, 2001, in three districts: Cau Giay, Tu Liem, Dong da of Ha Noi. There were 62 rubella cases aged from 1 to 25 years. Most of the cases were observed in age group 5-9 years (80,6%). The typical symptoms were fever (100%), rash (87,1%), itching (56,4%), coryza (35,5%). Serum samples from 9 cases were tested by MAC-ELISA, and all were positive.
Rubella ; Disease Outbreaks

Introduction: Children who develop any hypersensitivity reaction to eggs are routinely referred to hospital for Measles-Mumps-Rubella (MMR) vaccination as inpatients to prevent anaphylaxis. We aimed to study the association between hypersensitivity reactions after egg exposure and similar reactions after MMR immunisation; and examine the necessity of hospital admission for vaccination. Methods: A prospective observational study was conducted in Paediatric Department in Bukit Mertajam Hospital, Penang, between March and December 2014. Children referred from local polyclinics for inpatient MMR vaccination because of a history of egg allergy were recruited. The children were observed in the ward for post vaccination allergic reactions. Concurrently, a group of children without egg allergy was recruited from those admitted for other illnesses but had recent MMR vaccination at polyclinics. Parents of these children were interviewed and asked if they had observed any reactions post vaccination. In both groups, sociodemographics, medical history and family history of atopy were collected. Results: Eighty-seven subjects were recruited in this study. Fifty-four infants with egg allergy had previous mild allergic reactions after exposure to eggs or egg-related products. They were associated with a family history of egg hypersensitivity, personal history of acute gastroenteritis and upper respiratory tract infections. Two of them developed cutaneous rashes post vaccination during observation, but none developed anaphylactic or anaphylactoid reactions. Two infants among those without egg allergy had post vaccination fever. There was no association between egg allergy and hypersensitivity reactions to MMR vaccine (p=0.632). Conclusions: MMR vaccine can be safely administered to children with mild egg allergy, hence admission for vaccination in the hospital is not warranted. Risk stratification is required to ensure only infants with severe reactions will be admitted for vaccination.
Measles-Mumps-Rubella Vaccine