1.Combination Effect Of Argan Oil And Low Frequency Electromagnetic Field On Open Wound In Mice
Siti F. MASRE ; Muzamir M.K. ; Sabarina I. ; Jehan N. ; Yanti ROSLI
Malaysian Journal of Health Sciences 2018;16(Special Issue (Article)):41-45
This study was conducted to evaluate the effect of argan oil with the exposure of low frequency electromagnetic field (EMF)on open wound healing in mice. Eighteen male mice (20-40 g) were divided into three groups: phosphate buffer saline(PBS) as negative control, solcoseryl gel as positive control, and argan oil with the exposure of low frequency EMF, 1.2mT (treatment group). Full thickness wounds (4 mm diameter) were induced on the shaved dorsal of the mouse. All micewere sacrificed on day 12 after the final treatment. Macroscopic observation, wound contraction rate, histopathologyanalysis and total protein content were examined in this study. Results showed that wounds treated with argan oil andexposed to low frequency EMF has a significant increase in wound contraction rate (p < 0.05) and total protein content(p < 0.05). Moreover, histopathological analysis on the wound tissues displayed complete re-epithelization with thick anddense collagen fibers in the argan oil with low frequency EMF exposure treated group. In conclusion, topical treatment ofargan oil with low frequency EMF exposure yield a better healing progress and showed the ability to accelerate woundhealing.
2.Salmonella enteritidis abdominal aorta mycotic aneurysm presented with acute cholestatic jaundice: A case report and literature review
Wahab, A.A. ; Mohamed, N. ; Ding, C.H. ; Muttaqillah, N.A.S. ; Rosli, N. ; Mohammed, F.
Tropical Biomedicine 2023;40(No.1):23-28
Mycotic aneurysm is one of the extra-intestinal manifestations of Salmonella Enteritidis infection. The
diagnosis of this condition is challenging owed to its variation in clinical presentations. We presented
a case of a 54-year-old man with underlying diabetes mellitus and chronic smokers presented with
acute right flank pain and fever associated with mild jaundice. The initial laboratory investigations
suggested features of obstructive jaundice and urinary tract infection. The contrast enhancing computed
tomography of the abdomen revealed the presence of saccular mycotic aneurysm located at the
infrarenal abdominal aorta. The blood culture grew Salmonella Enteritidis which was susceptible to
ceftriaxone, trimethoprim-sulfamethoxazole, ciprofloxacin, ampicillin, and amoxicillin-clavulanic acid.
Intravenous ceftriaxone was initiated, and he underwent open surgery and artery repair at day 8 of
admission. He responded well to the treatment given and subsequently discharged home after completed
three weeks of intravenous ceftriaxone.