Objective To study the pharmacokinetics and the relative bioavailabi lity of micro-emulsified genistein in rabbits. Methods Rabbits received gastric gavage of micro-emulsified genistein and CMC-Na suspension of genistein. Then the genistein content in rabbit plasma at different time was determined by HPLC ,concentration-time curve was drafted,and the pharmacokinetic parameters and the relative bioavailability were calculated. Results The main parameters of mic ro-emulsified genistein and CMC-Na suspension of genistein were as follows:AU C0→10h being(24.90?1.24)and(10.71?0.86)?g?h?mL-1,Cmax being(4.02?0.20)a nd(0.99?0.04)?g?mL-1,Tmax being 2 h and 4 h,respectively. The relative bio availability of micro-emulsified genistein was 232.49 %. Conclusion Micro-emu lsified genistein system can improve the bioavailability of genistein evidently.

Objective To study the effects of using the polysiloxane impression material in the repair of the precise attachment.Method Using the Rapid polysiloxane impression material to make 37 work impressions,29 un-work impressions were made by alginate impression material.Results All the work impressions were eligible while there were 4 un-work impressions not eligible at the first time. Conclusion The effects of using the polysiloxane impression material in the repair of the precise attachment is satisfactory.