Objective To investigate the efficacy of transurethral resection of bladder tumor(TURBT).Methods From August 2001 to January 2007,26 patients with bladder tumor were treated with TURBT.Cutting electrode was used to resect the tumor,including also the normal mucous membrane,away from the base of the tumor by 0.5-1.0 cm,and reaching shallow muscle layer of the bladder in depth.The wound was treated with electrocoagulation.Postoperatively,drugs such as mitomycin were used through intravesical instillation for chemotherapy.Results Operation time was 15-90 min(52.5?37.5 min).One case had serious postoperative bleeding of the bladder,1 case of bladder perforation.Follow-up was conducted in 22 cases for 0.5-2 years,(mean:1 year).Six cases had recurrence in which 4 were in situ,the other 2 were ectopia.One of the recurrent cases had chyluria,treated with ligation of renal lymphatic tissue.Conclusions TURBT has advantages such as simple surgical manipulation,and reliable efficacy etc,in treating bladder tumor.

Objective To evaluate the efficacy of closed retroperitoneoscopic decortication of renal cysts.Methods Closed retroperitoneoscopic decortication of renal cysts was performed in 11 cases from December 1996 to September 2003 in this hospital.A 1~2 cm skin incision 2 cm above the iliac crest was made in the middle axillary line.A 10 mm trocar was introduced into the retroperitoneal cavity.A self-made water-filled balloon was used to create a retroperitoneal space for clearing the renal cyst.An electrocautery scalpel was used to excise the cyst wall until 0.5~1.0 cm away from the renal parenchyma.Results The procedure was successfully completed in 10 cases,with an operation time of 30~100 min(mean,77.5 min) and an intraoperative hemorrhage volume of 20~60 ml(mean,30.9 ml).A conversion to open surgery was required in 1 case because of difficult exposure of the renal cyst.Peritoneal injury was encountered in 1 case.The length of postoperative hospital stay was 6~9 days(mean,7.4 days).(Follow-up) observations in 7 cases for 7~26 months(mean,15.2 months) showed no recurrence of renal cyst under ultrasonography.Conclusions Closed retroperitoneoscopic decortication of renal cysts is a surgical option with little invasion,quick recovery,and good efficacy.

Objective To evaluate peri-operative clinical effects of transurethral electrovaporization of the prostate(TUVP) combined with transurethral resection of the prostate(TURP) versus open prostatectomy for benign prostatic hyperplasia(BPH).Methods A total of 156 cases of BPH were surgically treated in this hospital from November 1997 to December 2004,including 53 cases of TUVP combined with TURP(Combination Group) and 103 cases of open suprapublic prostatectomy(Open Group). Results There were no significant differences in the operation time between the two groups(90?70 min vs 108?68 min;t=(-1.550),P=0.123).The Combination Group was superior to the Open Group in the blood transfusion rate(8% vs 38%;?~2=16.109,P=0.000),the time to clear urine(2?1 d vs 4?1 d;t=-11.831,P=0.000),the postoperative catheterization time(10?8 d vs 19?10 d;t=-5.680,P=0.000),the time to get out of bed(6?4 d vs 20?10 d;t=-9.785,P=0.000),and the postoperative hospital stay(20?14 d vs 34?24 d;t=-3.914,P=0.000).The incidence of complications was higher in the Combination Group than in the Open Group(15.1% vs 2.9%;?~2=6.173,P=0.013).Conclusions TUVP in combination with TURP for benign prostate hyperplasia has advantages of little invasion and rapid recovery.

Objective To evaluate the clinical efficacy and safety of low-volume TURP on patients with BPH. Methods A total of 76 high-risk patients with BPH were treated with either standard TURP (Group 1,n=39) or low-volume TURP(Group 2,n=37).The operative duration,blood loss,postoperative irrigation time,IPSS,Qmax,postvoid urine residual volume (PURV) were comparatively evaluated. Results In Groups 1 and 2,the operation durations were (67.5?18.2)min and (16.4?3.5)min (P= 0.011);blood loss,(158.4?47.3)ml and (54.7?25.2)ml (P=0.013);postoperative irrigation time (4.9?1.8)d and (1.3?0.5)d (P=0.029);IPSS change (19.3?7.6) and (15.3?9.7)(P=0.46);Qmax (13.4?8.8)ml/s and (11.7?9.1)ml/s (P=0.79);PURV (134.9?68.6)ml and (163.8? 94.5)ml (P=0.17) respectively.31 cases in Group 2 (low-volume TURP) were followed up for 2 to 18 months (mean,10 months) with satisfactory results. Conclusions The low-volume TURP is effective and characterized by shorter operative duration,minimal-invasion and better tolerance for the high-risk patients with BPH.

Objective To analyze epidemiological characteristics of mitochondrial DNA12SrRNA A1555G mutation in Chinese populations with non-syndromic sensorineural hearing loss by the literature review and find the main actual deficiencies in course of epidemiological study.Methods From Cbmdisc and PUBMED database pulled out were all published epidemiological literatures about Chinese mtDNA12SrRNA A1555G mutation from 1996 to 2008.Reviewed were the primary data of these studies including the number of samples,demographic characteristics of the samples,mutation frequencies,interrelations between the mutation and aminoglycoside exposure and so on.Results 21 papers out of 25 were induded in this study.The patients had non-syndromic sensorineural hearing loss from 14 regions of China.A total of 3 473 were found including 230 patients with A1555G mutation and the average mutation frequency was 6.62%.The samples in each regions ranged from 72 to 802 and the reported mutation frequencies were from 0.67%-14.6%.The statistical discrepancy was significant among mutation frequencies in different regions by χ~2 test(P=0.0000).The number of patients with aminoglycoside antibiotics exposure was 739 including 100 with A1555G mutation in all literatures.The proportions in different regions were from 2.70% to 33.33% with the average of 13.53%.The average proportion was significantly higher than the mutation frequency in patients with non-syndromic sensorineural hearing loss.Conclusion Some deficiencies in epidemiological research Omutation in China included age,ethnic,and geographic bias,insufficiency of samples,inadequate randomization and so on.Researchers should focus with more efforts on the epidemiological characteristics of A1555G mutation in Chinese people.

OBJECTIVE: To explore a surgical method for the reconstruction of volar soft tissue defect and sensory and vascular repair in middle and far phalangeal digits. METHODS: From January 2016 to January 2020, a total of 14 patients , 9 males and 5 females, ages ranging from 22 to 69 years old, and with volar soft tissue defects in the middle and distal digits 2 to 4, underwent surgical reconstruction using the V-Y shaped flap with digital artery and nerve at the metacarpophalangeal joint. The defect area was (2.0~2.5) cm×(1.5 ~2.0) cm. The procedure involved the harvest of a V-Y shaped flap with the digital artery and nerve from the metacarpophalangeal joint. Flap design, dissection of blood vessels and nerves, and anastomosis with the digital artery and nerve were performed according to a standardized protocol., Functional exercise of affected finger was initiated 3 weeks postoperatively. Subsequent assessments were conducted to evaluate finger pulp sensation, shape and other relevant parameters. According to the upper extremity functional evaluation standard set up by Hand Surgery Branch of Chinese Medical Association, the surgical outcomes were evaluated. RESULTS: All 14 cases demonstrated successful tissue transplantation, , with immediate recovery of sensation observed in 10 cases with distal finger pulp defects. Four patients with middle phalangeal defects experienced gradual sensory recovery within 2 to 3 months postoperatively. Thirteen patients were followed up for a mean duration of (8.8 ± 4.49) months, during which satisfactory outcomes were observed. The average two-point resolution of the finger pulp was 4-6mm, and sensory function evaluation yielded a score of S3 or above. Patients exhibited realistic finger shape, normal skin color and temperature, good wear resistance, and cold resistance. Furthermore, finger joint function was essentially normal. CONCLUSION The V-Y shaped flap with digital artery and nerve at the metacarpophalangeal joint offers a suitable solution for repairing the defect of the middle or distal phalangeal finger. This technique is characterized by its simplicity, low risk, and favorable outcomes, including restored finger shape, blood supply and sensation. Moreover, high patient satisfaction was achieved.
Male ; Female ; Humans ; Young Adult ; Adult ; Middle Aged ; Aged ; Plastic Surgery Procedures ; Skin Transplantation ; Finger Injuries/surgery* ; Treatment Outcome ; Soft Tissue Injuries/surgery* ; Fingers/surgery* ; Ulnar Artery/surgery* ; Metacarpophalangeal Joint/surgery*

Effects of carbon sources (Na2CO3, NaHCO3 and glucose) and concentration of NaHCO3 on the growth density and lipid contents of Nannochloropsis oculata were studied. N. oculata preferred inorganic carbon to glucose, the growth density and lipid content of algae cultured with NaHCO3 were higher than that with glucose. The effects of concentration of NaHCO3 on growth density and lipid content were related to inoculation density and nitrogen level. In high nitrogen level, the concentration of NaHCO3 had little effect on the growth density, but in low nitrogen level, the growth density increased at first, and then decreased with the increase of concentration of NaHCO3. Based on the results we suggest that an optimum ratio of carbon to nitrogen was existed. Furthermore, we found the optimum ratio was changed with inoculation density. The optimum ratio of carbon to nitrogen was 3 when inoculation density was OD440 of 0.10, the optimum ratio increased to 5 with OD440 of 0.70. Concentration of NaHCO3 and ratio of carbon to nitrogen had significant effects on the lipid content and productivity. Lipid content reached the highest value when the ratio of carbon to nitrogen was 1 with experimental range of nitrogen level and inoculation density. The lipid productivity was 56.7 mg/(L.d) , and the EPA productivity was 6.5 mg/(L.d) at optimum cultivation condition with NaHCO3 as carbon source, the ratio of carbon to nitrogen at 1, the concentration of NaNO3 at 0.225 g/L, and the inoculation density with OD440 of 0.70.
Carbon ; chemistry ; metabolism ; Culture Media ; Culture Techniques ; methods ; Fatty Acids ; metabolism ; Fermentation ; Glucose ; metabolism ; Lipid Metabolism ; Microalgae ; growth & development ; metabolism ; Population Density ; Stramenopiles ; growth & development ; metabolism