Objective:To analyze the unreasonable medical orders at the pharmacy intravenous admixture service ( PIVAS) of our hospital to improve clinical medication. Methods: The medical orders from January to October in 2013 were collected and reviewed, the unreasonable medical orders were analyzed and the results were informed to the clinics. Results:Totally 323 unreasonable medical orders were found, which accounted for 0. 03%. The unreasonable aspects included unreasonable compatibility, input error, irregular medical orders, over dosage or concentration, unsuitability between dosage and age and the disproportion between dosage and diagno-sis. Conclusion:The irrationality in intravenous medical orders still exists in clinics, which shows drug use risks. The unreasonable medical orders can be avoided or reduced through the review of medical orders by pharmacists at PIVAS to improve the safety of clinical drug use.

Objective To explore the clinical feasibility and safety of early intervention for severe stenosis of non-infarct related artery(non-IRA)in patients with acute ST-segment elevation myocardial infarction(STEMI) and multi-vessel disease(MVD)after successful primary percutaneous coronary intervention(PCI)for infarct-asso-ciated artery(IRA). Methods From May 1st,2011 to December 30th,2016,165 patients with STEMI and MVD were enrolled in our study. After the completion of primary PCI in IRA ,75 patients still in the hospital agreed to undergo a second staged PCI in severe stenosis of non-infarct arteries. We analyzed the in-hospital adverse events ,the length of hospital stay and clinical outcomes during the follow-up in the study population. Results There was no significant difference in the incidence of adverse events between the two groups during hos-pitalization. However,compared to patients treated with the IRA-only PCI,those treated with early intervention for severe stenosis of non-IRA was associated with greater benefits for clinical outcomes(including rehospitalization for heart failure,rehospitalization for ACS,recurrent angina pectoris,necessity for reintervention)during the follow-up except for the all-cause mortality. Conclusion Early intervention for severe stenosis of non-IRA is a feasible and safe procedure in patients with acute STEMI and MVD after successful primary PCI.