OBJECTIVE:To explore the contents of synephrine in raw Fructus Aurantii Immaturus and its processed products.METHODS:HPLC was used for the quantitative analysis of raw Fructus Aurantii Immaturus and its processed products;C 18 was used as the Chromatographic column;methanol-water(43∶57)which contained0.1%phosphoric acid and0.1%soldium dodecyl sulfonate was used as the mobile phase with a detected wavelength at275nm,column temperature at40℃and a flow speed at1.0ml/min.RESULTS:Synephrine contents of the vinegar-fried product was the highest and that of the alcohol-fried product was the lowest.CONCLUSION:There is a significant difference in intrinsic quality among various processed products of Fructus Aurantii Immaturus.

Objective To investigate the value of magnetic resonance imaging of heart in diagnosis of unstable angina pectoris.Methods A total of 24 patients with unstable angina pectoris including 15 male and 9 female confirmed by coronary angiography (CAG) were enrolled.All 24 patients were scanned by cardiac magnetic resonance imaging ( CMR),and then the analyses of the first pass images and the delayed contrast enhancement images were carried out for comparison.The findings of cardiac structure,cardiac function,myocardial ischemia,myocardial necrosis,myocardial edema were taken for answering to the images made by echocardiography (UCG) and coronary angiography (CAG) linked with conventional examinations for the diagnosis of coronary disease.Results Compared with the UCG,CMR provided more detailed information about the right ventricle,and the information about left ventricular structure and function given by UCG was very good consistent with that offered by CMR,and CMR could detect myocardial ischemia,myocardial edema and the myocardial necrosis,which were of good consistency with findings often observed by conventional inspection methods.Conclusions Cardiac magnetic resonance imaging (CMR) is of high value in diagnosis and evaluation of unstable angina pectoris and is far superior over other conventional methods for examinations of unstable angina pectoris.

OBJECTIVE:To prepare Qingrejieduhuazhuo tablets and establish the standard of quality control.METHODS:The content of baicalin in the product was determined with HPLC method.RESULTS:The linear range of baicalin concentra?tion was0.128～0.642?g/ml and correlation coefficient was0.9997.The average recovery of sample was98.31%with a RSD of0.82%(n=6).CONCLUSION:The method is suitable for the quality control of Qingrejieduhuazhuo tablets.

OBJECTIVE: To explore the inner quality of two kinds of single decoction solution. METHODS: The methods of HPLC, UV, TLC etc. were used for the qualitative and quantitative analysis. RESULTS: The contents of main components in single decoction solution of herbs in granule form were higher than those in slice form- CONCLUSION: The decocting rate of herbs in granule form is higher. It is worth popularizing.

OBJECTIVE:To study the stability of Yinzhihuang injection(YZH) mixed with 5% glucose solution,10% glucose solution,glucose in normal saline,normal saline and Ringer's solution.METHODS:After YZH mixed with infusion fluid under room temperature,the contents of baicalin were determined with UV-spectrophotometry at different time periods within 24h,the apperance was observed,the pH values of baicalin were detected and identified by TLC.RESULTS:Under room temperature,after YZH mixed with Ringer's solution,the pH value of baicalin was markedly changed and a lot of white particles appeared;after YZH mixed with GNS,no changes of pH value and content of baicalin were found within 24h.When YZH mixed with other 3 kinds of infusion fluid,there were no changes in pH value and content of baicalin within 2h,however,in mixing with NS,the number of insoluble particles produced was beyond the standard.CONCLUSION:YZH should not be mixed with NS or Ringer's solution but it is compatible with 5%GS,10%GS and GNS,however,it should be mixed with them just before use and used up within 2h.

OBJECTIVE:To set up the quality standard for Xiaoyan San METHODS:Rheum officinale,Flos Lonicerae and Capejasmine were identified by TLC method The contents of emodin and chrysophanol in Xiaoyan San were determined by HPLC RESULTS:The linear range and average recovery of emodin was 21 12～105 6ng/ml(r=0 9 998,n=5) and 98 78%;The linear range and average recovery of chrysophanol were 29 28～146 4ng/ml(r=0 9 998,n=5) and 99 45% respectively CONCLUSION:The method is convenient,accurate and practicable It can be used for quality control in production of Xiaoyan San

AIM: To develop a method for determining contents of ginsenoside Rb_1,ginsenoside Rg_1 and notoginsenoside R_1 in Sanxue Mingmu Tablet(Radix et Rhizoma Notoginseng,Pheretima,Herba Leonuri,Rhizoma Imperatae,etc.). METHODS: The contents of ginsenoside Rb_1,ginsenoside Rg_1 and notoginsenoside R_1 were separated by gradient elution on Hypersil ODS C_(18) column(5 ?m ? 4.6 mm?100 mm) as stationary phase;acetonitrile and water as gradient mixed mobile phase;detected at 203 nm wavelength;(25 ?C) of column temperature and 1.0 mL/min of mobile rate. RESULTS: Ginsenoside Rb_1,ginsenoside Rg_1 and notoginsenoside R_1 had good linearities(r=0.999 9;n=6) at the ranges of 1.480 0-14.800 ng;0.372 0-3.720 ng and 1.072 0-10.720 ng.The average recoveries were 98.44%(RSD=0.96%);99.02%(RSD=0.94%);97.95%(RSD=(1.02%)),respectively. CONCLUSION: This method is high in column efficiency and satisfactory for isolation and repeatability,the result is accurate.It can be adopted for quality control of Sanxue Mingmu Tablet.

OBJECTIVE:To compare the contents of hesperidin in raw Fructus Aurantii Immaturus and its processed products.METHODS:HPLC was used for the quantitative analysis of raw Fructus Aurantii Immaturus and its processed products.RESULTS:The content of hesperidin in vinegar-fried Fructus Aurantii Immaturus was the highest and that in the bran-fried Fructus Aurantii Immaturus was the lowest.CONCLUSION:It is suggested that there exist significant differences in intrinsic quality among various processed products of Fructus Aurantii Immaturus.

Objective:To optimize the conditions in the extraction process of Yushaoshang liposomal gels. Methods: Using the content of hydrobererine and extract yield as the indices, the optimum extraction conditions were screened by orthogonal test. Results:The optimum extraction conditions were as follows:Rhizoma coptidis was crashed into small particles as 10 mesh sieve, heating extrac-ted three times with 10-fold,8-fold and 8-fold water, and extracting 3h, 2h and 2h,respectively. Conclusion:The extraction technology is reliable and available in the preparation of Yushaoshang liposomal gels.

OBJECTIVE:Comparing the components in decoctions of raw Fructus Viticis and its processed products.METHODS:The methods of UV - spectrophotometry,TLC, etc. were used for the qualitative and quantitative analysis of decoctions of raw Fructus Viticis and its processed products.RESULTS:The content of total flavone in the steamed Fructus Viticis decoction was the highest and that in the carbonated Fructus Viticis decoction was the lowest;the amount of water extract substances of honey- processed Fructus Viticis was the highest and that of carbonated Fructus Viticis was the lowest .CONCLUSION: It is suggested that there exist significant differences in intrinsic quality among various processed products of Fructus Viticis.