1.Effects of n-Butanol Extract of Xanthoceras Sorbifolia Bunge on Rat Model with Adjuvant Arthritis and its Mechanism
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(04):-
Objective:To study the effects of n-Butanol Extract (BEX)of Xanthoceras Sorbifolia Bunge on rat model with adjuvant arthritis(AA) in rats and its mechanism .Methods: Rat model of adjuvant arthritis(AA) was induced by FCA. Hind paw swelling was observed to evaluate the effect of BEX and phagocytic function of monocyte-macrophage system, antibody level and delayed hypersensitivity were examined to explore its mechanism. Results: BEX can inhibit the primary and secondary hind paw edema and improve the general symptoms (P
2.Advances in the study on histamine
Rong KUANG ; Lingfei AN ; Yulan LIU
Chinese Pharmacological Bulletin 1986;0(05):-
The effect of histamine on cardial vascular ,gland,tumor and allergic reaction were reviewed and the development of its antagonist is summarized.
3.Pharmacodynamics study on Fufangdaqinye Mixture
Sheming ZHU ; Xioujua CHAI ; Rong KUANG ;
Chinese Traditional Patent Medicine 1992;0(11):-
AIM: To study the pharmadynamics in association with the clinical effect of Fufangdaqinye Mixture. METHODS: The method of this study included anti fever, anti inflammatory and anti bacteria experiment. RESULTS: Fufangdaqinye Mixture was quite effective for the fever induced by endotoxin in rabbit, and preserved those mice from death caused by abdominal injection of staphylococcus aureus and itemophilus influenze and had a effect against staphylococcus aures, hemophilus influenze, peumococcus and streptococcus A and B. Fufangdaqinye Mixture could significantly inhibit the foot swelling and significantly inhibit the increased penetrability of abdominal capillary vessel induced. CONCLUSION: Fufangdaqinye Mixture has a curative effect of anti fever, anti bacteria and anti inflammation.
4.Minute on the 5th Guangdong Provincial Conference of integrated medicine on deficiency syndrome and geriatrics.
Li ZHANG ; Rong-hua ZHANG ; Bing-kuang ZHU
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(6):478-479
Aged
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Animals
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China
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Drugs, Chinese Herbal
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therapeutic use
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Humans
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Osteoporosis
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drug therapy
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Phytotherapy
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Stroke
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drug therapy
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Yang Deficiency
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drug therapy
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Yin Deficiency
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drug therapy
5.Determination of Imperatorin in Jiedu Tongqiao Pills by HPLC
Ke CHEN ; Ming KUANG ; Rong YI ; Ju CHEN
China Pharmacy 1991;0(03):-
OBJECTIVE: To determine imperatorin as the active ingredient of Angelica dahuricae in Jiedu tongqiao pills by HPLC. METHODS: The separation was performed on Waters Symmetryshielb33 C18(250 mm?4.6 mm,5 ?m) column with detection wavelength of 248 nm. The mobile phase consisted of methanol-water (65 ∶ 35) with flow rate of 1.0 mL?min-1.RESULTS:The linear range of imperatirin were 0.15~1.35 ?g. The average recovery was 100.4%(RSD=1.89%,n=9).CONCLUSION: The method is simple, accurate and reproducible for quality control of Jiedu tongqiao pills.
6.Evaluation of 131 I biokinetics and its absorbed dose in patients with metastatic differentiated thyroid carcinoma
Bin LIU ; Rong TIAN ; Xiaohong OU ; Rui HUANG ; Anren KUANG
Chinese Journal of Nuclear Medicine and Molecular Imaging 2016;(1):63-66
Objective To investigate the biokinetics of 131 I and its absorbed dose in patients with metastatic DTC. Methods Forty?one patients with metastatic DTC who were referred to 131 I therapy were prospectively recruited from September 2009 to September 2011. Scintigraphic images were serially acquired after the ingestion of 131I (3.70-9.25 GBq) to assess the biokinetics. CT was used to measure the masses of the DTC lesions. Calculation of absorbed doses to DTC lesions was based on the Medical Internal Radiation Dosimetry formula of the Society of Nuclear Medicine and Molecular Imaging. Kruskal?Wallis rank sum test was used to compare the differences of absorbed dose among different tumor deposits. Results In total, 59 io?dine?avid metastatic lesions (35 in cervical lymph node, 17 in lung and 7 in bone) in 41 patients were evalu?ated and the mean absorbed dose of DTC lesions was (10.4±6.5) Gy/GBq, with range of 0.1 to 136.2 Gy/GBq. The median absorbed dose was 11.3 Gy/GBq for lymph node metastase, 10.1 Gy/GBq for lung metastases and 9.6 Gy/GBq for bone metastases. There were no statistically significant differences in absorbed doses a?mong the metastases of lymph node, lung and bone ( Z=0.907, P>0.05) . Conclusion A wide inter?lesion variation of absorbed dose to metastatic DTC is observed.
7.Application of extracorporeal shock-wave therapy (ESWT) in delayed unions and non-unions
Muqing LIU ; Xia GUO ; Shicun KUANG ; Shuhuan WANG ; Guowe RONG
Journal of Peking University(Health Sciences) 2004;0(03):-
Nonunion remains a major complication after skeletal trauma. In the last decade, extracorporeal shock wave therapy has become a common tool for the treatment of delayed unions or non-unions. With the help of a review of the literature, the current author gave an overview of indications, choices of devices, success rates and complications for ESWT in the treatment of non-unions. The conceivable mechanism was also outlined.
8.Comparative Study on 100 Cases of Chronic Hepatitis B Treated with Chinese Traditional and Western Drugs
Jing ZHANG ; Yunshan KUANG ; Yaqiu RONG ; Weizhong CHENG ; Cuizhu YU ;
Journal of Traditional Chinese Medicine 1993;0(07):-
Fifty Cases of chronic B—hepatitis were treated withTCM based on differentiation of syndromes and com-pared with a control group of 50 cases treated withwestern remedies.Results showed that for the treatinggroup,the rate of negative return of HBeAg was64%,and the rate of positive return of HBe was 48%,while that of the control group were 20% and 10% re-spectively.
9.Changes in chemokine receptor 4, interleukin-6, and collagen X expression in the ATDC5 cell line stimulated by cyclic tensile strain and stromal cell-derived factor-1.
Bin KUANG ; Qingyu WANG ; Rong SONG ; Yanyan SUN ; Zhiguo CHAI ; Yinzhong DUAN ; Juan DAI
West China Journal of Stomatology 2014;32(6):592-595
OBJECTIVEThis study further explores the stromal cell-derived factor-1 (SDF-1)/chemokine receptor 4 (CXCR4) signaling axis mechanism in temporomandibular joint osteoarthritis (OA) by detecting the changes in CXCR4, interleukin (IL)-6, and collagen X expression in the ATDC5 cell line stimulated by the cyclic tensile strain and SDF-1.
METHODSInsulin-transferrin-selenium (ITS) was used to induce ATDC5 cells to differentiate into chondrocyte-like cells. After three weeks, the cells were divided into two groups: those with and without cyclic tensile strain. These groups were further divided into the negative control and SDF-1 groups. Strain force of 20% was applied. After 12 h, the total proteins were extracted from cells of the four groups, and Western blot analysis was used to detect the changes in CXCR4, IL-6, and collagen X expression.
RESULTSSDF-1 could enhance CXCR4, IL-6, and collagen X expressions in the chondrocytes, and 20% tensile strain force could further upregulate the three factors.
CONCLUSIONUnder abnormal tensile force, SDF-1 can upregulate its specific receptor CXCR4, thus increasing its-binding efficiency and resulting in the activation of the SDF-1/CXCR4 axis. This condition enhances the expressions of IL-6 and other inflammatory factors and directly damages to cartilage tissue. Such damage directly promotes chondrocyte hypertrophy, which enhances collagen X expression.
Cell Differentiation ; Cell Line ; Chemokine CXCL12 ; Collagen ; Humans ; Interleukin-6 ; Receptors, CXCR4 ; Signal Transduction ; Stromal Cells
10.Comparison of normal male puborectalis by ultrasound and magnetic resonance imaging
Rong WU ; Bing HU ; Ying HUANG ; Xudong JIANG ; Tao YING ; Bulin ZHANG ; Shengli KUANG
Chinese Journal of Ultrasonography 2008;17(10):872-875
Objective To afford an new effective imaging technique for the morphological observation of the normal male pelvic floor by observing the normal male puborectalis with transrectal ultrasound and magnetic resonance imaging (MRI). Methods Thirty-six normal males were examined by transrectal ultrasound and MRI,data of puborectalis were recorded and compared including starting point, end point,appearance, structure, thickness and the relationship with peripheral organs. Results The results including the appearance,direction and internal echo of puborectalis and the relationship with peripheral organs can be clearly displayed by transrectal ultrasound compared with MRI. The thickness of right and left puborectalis at rest measured in ultrasound and in MRI were (6.22±0.57)mm, (6.19±0.59) mm, (6.20±0.61) mm and (6.17±0.53) mm, respectively. The thickness by two methods and two sides had no significant differences (P>0.05). The thickness of puborectalis measured by two methods did not correlate with age,height,body weight,the volume of prostate and interspinal diameter respectively. Conclusions Transrectal ultrasound is a new imaging method to observe male puborectalis. Identification for nomal puborectalis sonography is the foundation of diagnosis pelvic floor disease.