1.A rare case of mucinous adenocarcinoma of the bladder: A case report.
Ryan Josef Tuazon ; Romeo Lloyd T. Romero ; Meliton Alpas
Philippine Journal of Urology 2021;31(2):93-96
Adenocarcinoma represents 0.5 to 2% of all malignant tumors of the bladder, and the mucinous subtype is extremely rare as a primary vesical lesion. This is the case of a 50-year-old male who presented with dysuria with occasional hematuria, underwent cystoscopy, transurethral resection of the bladder tumor, with the subsequent diagnosis of Mucinous adenocarcinoma of the bladder. He then completed neoadjuvant chemotherapy but eventually underwent cystoprostatectomy, urethrotomy with extended bilateral pelvic lymph node dissection due to tumor progression.
2.A rare case of mucinous adenocarcinoma of the bladder: A case report.
Ryan Josef Tuazon ; Romeo Lloyd T. Romero ; Meliton Alpas
Philippine Journal of Urology 2021;31(1):1-5
Adenocarcinoma represents 0.5 to 2% of all malignant tumors of the bladder, and the mucinous subtype is extremely rare as a primary vesical lesion. The patient is a case of a 50-year-old male who initially presented with dysuria with occasional hematuria. A CT scan was done and showed bladder new growth. Cystoscopy Transurethral Resection of the bladder tumor was done revealing mucinous adenocarcinoma of the bladder. He then completed neoadjuvant chemotherapy with Pacitaxel and Cisplatin for 4 cycles, however repeat CT scan with contrast post chemotherapy showed progression of the adenocarcinoma. Due to the possibility of a primary lesion in the gastrointestinal tract, colonoscopy was performed revealing sessile serrated adenoma, as were tumor markers CA 19-9, CA 125, alpha-fetoprotein, and CEA, all of which without any abnormal results. He eventually underwent cystoprostatectomy and urethrectomy with extended bilateral pelvic lymph node dissection. The margins and lymph nodes were negative for tumor invasion. Adenocarcinoma is diagnosed mainly on histopathology and with the help of Immunohistochemistry (IHC). Once the diagnosis is confirmed, the radical surgery should be advised which could improve survival and disease progression.
3.Penile calciphylaxis: A case series in a Tertiary hospital in the Philippines.
Ralph Rabanal ; Romeo Lloyd T. Romero ; Meliton Alpas ; Eli Paulino F. Madrona ; Rodney M. Del Rio ; Karl Marvin M. Tan
Philippine Journal of Urology 2021;31(1):19-22
Penile calciphylaxis is a rare penile condition associated with end-stage renal disease and is found in 1-4% of hemodialysis patients. The condition has an overall mortality of 64%. Literature has yet to provide a gold standard for the management of this condition. The first case is a 58-year-old diabetic and hypertensive on hemodialysis who presented with ulcerating lesions on the penis. The patient underwent partial penectomy. The patient contracted pneumonia during recovery and expired 3 months after the procedure. The second case is a 56-year-old diabetic with end stage renal disease on dialysis who presented with dry gangrene of the penis. He underwent partial penectomy and was sent home after recovery.
4.Male lower urinary tract symptoms in correlation with age, quality of life scores, parameters of uroflowmetry and prostate size, a single institution study.
Romeo Lloyd T. Romero ; Alfredo S. Uy Jr. ; Eli Paulino F. Madrona ; Rodney M. Del Rio ; Meliton D. Alpas ; Karl Marvin M. Tan
Philippine Journal of Urology 2019;29(1):23-29
OBJECTIVE:
To correlate male lower urinary tract symptoms between age, quality of life scores,parameters of uroflowmetry and prostate size.
PATIENTS AND METHODS:
Two hundred eight males were included in this study. Uroflowmetry parameters,age, International Prostate Symptom Score (IPSS), Quality of Life (QoL) scores and prostate sizewere gathered. For correlation, distribution of age, uroflowmetry parameters and prostate size werefirst compared to IPSS. Analysis of variance was used to compare age of patients, while Kruskall-wallis test was used to compare the QoL, uroflowmetry parameters, and prostate size on each IPSSgroups. Ordinal logistic regression analysis was used to correlate IPSS to age, quality of life,uroflowmetry parameters, and prostate size both for multivariate and univariate analysis.
RESULTS:
There was no significant correlation between age and IPSS. However, on profile distribution,the age distribution between symptom scores were statistically similar. Qol scores were directlyproportional to IPSS. Thus, patients with a worse QoL score were more likely to have higher IPSS.Qmax scores decreased as symptom severity increased. Patients with higher Qmax scores are lesslikely to have higher IPSS scores. Voided volume was observed to decrease as IPSS severity increased,but this was not statistically significant. Patients with higher post void residual scores were morelikely to have higher IPSS. There was also no significant correlation between prostate size and IPSS.
CONCLUSION
There were no significant correlation between IPSS and age, voided volume and prostatesize. On the other hand, patients with a worse QoL score and a high post void residual had higherIPSS. Patients with a high Qmax, are less likely to have an elevated IPSS.
5.The impact of covid-19 pandemic on urology residency training programs in the Philippines: A descriptive study.
Daryl K. Koa ; Alfredo Uy Jr. ; Eli Paul F. Madrona ; Rodney M. Del Rio ; Meliton Alpas III ; Karl Marvin M. Tan ; Romeo Lloyd T. Romero ; Ralph Rabanal ; Ryan Josef Tuazon ; Jan Ernest Guy G. Yadao
Philippine Journal of Urology 2021;31(1):49-54
OBJECTIVE:
To provide an overview on the impact of healthcare disruption by the COVID-19 pandemic to urology training programs in the Philippines.
METHODS:
A survey questionnaire was used in collaboration with the study done by Rosen, et al. last May 2020. Telephone survey of the study population was done determining the status of resident staffing, workload, health/wellness, and didactics. Numerical and categorical data were analyzed and descriptive statistics are provided.
RESULTS:
All the observations on resident time in the workplace, including assignment to teams (81%), redeployment responses (55-97%), and remote clinical work (65%) were significant. Fifty one percent of residents have decreased research load. Eighty one percent have didactics in small groups. Fifty-five percent have 1 to 2 Video-based learning/conferences per week (p=0.007) followed by those with 3-4 with 98% (p=0.120) and those with >5 with only 6% (p=0.729). For Resident health and wellness, 87% of the residents were exposed to COVID-positive patients, but only 8% of residents were COVID positive (p=0.591). Lastly, 59% of the participants do not have access to wellness programs.
CONCLUSION
Data from respondents revealed significant changes in the different aspects of the present study. Urology residents spent more time away from their specialties, and have been re-deployed to COVID-19 floors. Ambulatory services, conferences, educational lectures have mostly shifted to virtual platforms. Resident concerns for COVID-19 exposure have been addressed properly; however, wellness programs have not been widely available for residents. As a first national survey, the present study may give significant insights on program changes and may be used as preliminary data for future studies.
Philippines
6.Inguinoscrotal bladder hernia with cystolithiasis.
Jan Ernest Guy G. Yadao ; Romeo Lloyd T. Romero ; Brian Severo P. Blas ; Karl Marvin M. Tan
Philippine Journal of Urology 2020;30(2):62-65
A hernia occurs when an organ or fatty tissue squeezes through a weak spot in surrounding muscle or connective tissue, called fascia. Hernia is classified as inguinal, incisional, femoral, umbilical, or hiatal. The bladder may herniate in 1%–3% of the cases through the inguinal canal. A herniated bladder with calculus is a more unique condition that has only 3 reported cases. Reported here is a case of a 65-year-old male with a known case of left bladder inguinal hernia. He presented with an inguinoscrotal bulge at the left groin and severe lower urinary tract symptoms, associated with a need to squeeze his scrotum to complete his voiding. A Computed Tomography scan revealed inguinoscrotal bladder hernia, left with urinary bladder calculi, and an enlarged prostate gland. The patient underwent cystoscopy, inguinal exploration left, cystolithotomy, hernioplasty left. Inguinoscrotal hernia of the bladder is a rare pathology and often goes unrecognized in during surgical hernia repair. Preoperative identification of bladder hernia is essential to prevent iatrogenic trauma and severe complications. It is mandatory for general surgeons and urologists to keep in mind this rare condition during surgical repair of inguinal hernia.