A rapid tissue preparation to establish the diagnosis of surgical specimens was reported. The specific reason to request such a preparation usually relates to a suspicion of a neoplastic lesion. This study was conducted to evaluate the role of scrimp technique, a modification of imprint cytology, in the rapid intraoperative diagnosis of tumors as compared with frozen section. Scrape and imprints of tumors were made from 86 unfixed specimens at the time of frozen section. Rapid and permanent staining methods were employed and the accuracy of diagnosis was compared with frozen and paraffin preparations. The results showed that the sensitivity and specificity of scrimp preparation were 95% each as compared with frozen section which has 98% and 100% respectively which manifested a negligible inferiority over frozen section. This technique was simple, fast, easy, and reliable and does not require special instruments or time consuming set-up. While not meant to replace frozen section, it can be an excellent adjunct or alternative especially in remote and secondary hospitals unequipped with sophisticated apparatus. (Author)

Human ; Male ; Female ; Aged ; Middle Aged ; Adult ; Adolescent ; Child ; Frozen Sections ; Paraffin ; Sensitivity And Specificity ; Cytodiagnosis ; Neoplasms ; Staining And Labeling

Background : The data on the prevalence and distribution of polyps in Asians is limited with conflicting data about the most common type. Objective: To obtain recent data about the histologic types of endoscopically labeled as polyps by colonoscopy and correlate with the clinico-pathologic profile Method: Retrospective cross-sectional review of histopathologic and endoscopic reports of colonoscopy with biopsy of colonic polyps of patients in the University of Santo Tomas Hospital (January 2014- December 2016). Results: 3910 colonoscopies were performed and a total of 302 patients were retrieved and 500 polyps were resected. The most common indication was hematochezia and hemorrhoids. The colonic polyps were solitary in 36% of the cases. Majority were seen in 50-69 years old, left sided region (78%), particularly the sigmoid (37%), and sessile (77.3%). The most common type is tubular adenoma (45%) and majority of the adenomatous polyps were seen in the sigmoid. There is significant association between age and presence of an adenomatous polyp where ≥70 years old are about 2.5 times more likely to have adenomatous polyp and pedunculated polyps are 2 times more likely to be adenomatous. There is no significant association between presence of an adenomatous polyp and polyp size and gender. Conclusion The type and distribution of colorectal polyps are similar with others and vigilant approach of the left side should be exercised. Absence of any significant difference between size and adenomatous nature necessitate the need for early identification and removal of colorectal polyp in preventing morbidity and mortality from cancer.
Colonoscopy

No abstract available.
Adrenal Glands* ; Eosinophils* ; Leiomyosarcoma*

Objective: To describe the cytopuncture microbiopsy (CM) technique performed during transcanalicular endoscopic lacrimal duct recanalization (TELDR) in patients with primary acquired nasolacrimal duct obstruction (PANDO) as an alternative to open biopsy, the standard method used in collecting specimen. Methods: This is a noncomparative, interventional case series with histopathologic correlation. Patients diagnosed with complete PANDO who underwent TELDR with balloon dacryoplasty and silicone intubation with CM at University of Santo Tomas Hospital from October 2014 to January 2017 were included. Results: Twenty (20) tissue specimens from the lacrimal sac and nasolacrimal duct were obtained from 18 patients. There were 16 females and 2 males included in the study. Mean age was 57.5 years. All specimens revealed few clusters of benign epithelial cells with few degenerated mononuclear cells and lymphocytes, and singly scattered lymphocytes that are set in fibrinous background. Tissue cytology studies were negative for malignant cells. Conclusion CM is a minimally invasive procedure that offers an alternative to open biopsy technique that can be done routinely during TELDR.
Dacryocystorhinostomy ; Lacrimal Apparatus Diseases