1.Microfilaria in hydrocele fluid cytology.
Patricia Ann Chandran ; Gita Jayaram ; Rohela Mahmud ; A Khairul Anuar
The Malaysian journal of pathology 2004;26(2):119-23
Filariasis, a parasitic infection endemic in parts of India, Myanmar, islands of the South Pacific, West and East Africa and Saudi Arabia can be diagnosed from various types of cytopathological specimens. This case documents the detection of filarial infection from hydrocele fluid cytology in a 30-year-old Myanmar migrant worker in Malaysia.
Liquid substance
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Cellular aspects of
;
Infection as complication of medical care
;
Microfilaria
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Myanmar
2.Epidemiological Characteristics of Strongyloidiasis in Inhabitants of Indigenous Communities in Borneo Island, Malaysia.
Romano NGUI ; Noor Amira Abdul HALIM ; Yamuna RAJOO ; Yvonne AL LIM ; Stephen AMBU ; Komalaveni RAJOO ; Tey Siew CHANG ; Lu Chan WOON ; Rohela MAHMUD
The Korean Journal of Parasitology 2016;54(5):673-678
Epidemiological study on strongyloidiasis in humans is currently lacking in Malaysia. Thus, a cross-sectional study was carried out to determine the prevalence of Strongyloides stercoralis infection among the inhabitants of longhouse indigenous communities in Sarawak. A single stool and blood sample were collected from each participant and subjected to microscopy, serological and molecular techniques. Five species of intestinal parasites were identified by stool microscopy. None of the stool samples were positive for S. stercoralis. However, 11% of 236 serum samples were seropositive for strongyloidiasis. Further confirmation using molecular technique on stool samples of the seropositive individuals successfully amplified 5 samples, suggesting current active infections. The prevalence was significantly higher in adult males and tended to increase with age. S. stercoralis should no longer be neglected in any intestinal parasitic survey. Combination of more than 1 diagnostic technique is necessary to increase the likelihood of estimating the ‘true’ prevalence of S. stercoralis.
Adult
;
Borneo*
;
Cross-Sectional Studies
;
Enzyme-Linked Immunosorbent Assay
;
Epidemiologic Studies
;
Humans
;
Malaysia*
;
Male
;
Microscopy
;
Parasites
;
Polymerase Chain Reaction
;
Prevalence
;
Strongyloides stercoralis
;
Strongyloidiasis*
3.Epidemiological Characteristics of Strongyloidiasis in Inhabitants of Indigenous Communities in Borneo Island, Malaysia.
Romano NGUI ; Noor Amira Abdul HALIM ; Yamuna RAJOO ; Yvonne AL LIM ; Stephen AMBU ; Komalaveni RAJOO ; Tey Siew CHANG ; Lu Chan WOON ; Rohela MAHMUD
The Korean Journal of Parasitology 2016;54(5):673-678
Epidemiological study on strongyloidiasis in humans is currently lacking in Malaysia. Thus, a cross-sectional study was carried out to determine the prevalence of Strongyloides stercoralis infection among the inhabitants of longhouse indigenous communities in Sarawak. A single stool and blood sample were collected from each participant and subjected to microscopy, serological and molecular techniques. Five species of intestinal parasites were identified by stool microscopy. None of the stool samples were positive for S. stercoralis. However, 11% of 236 serum samples were seropositive for strongyloidiasis. Further confirmation using molecular technique on stool samples of the seropositive individuals successfully amplified 5 samples, suggesting current active infections. The prevalence was significantly higher in adult males and tended to increase with age. S. stercoralis should no longer be neglected in any intestinal parasitic survey. Combination of more than 1 diagnostic technique is necessary to increase the likelihood of estimating the ‘true’ prevalence of S. stercoralis.
Adult
;
Borneo*
;
Cross-Sectional Studies
;
Enzyme-Linked Immunosorbent Assay
;
Epidemiologic Studies
;
Humans
;
Malaysia*
;
Male
;
Microscopy
;
Parasites
;
Polymerase Chain Reaction
;
Prevalence
;
Strongyloides stercoralis
;
Strongyloidiasis*
4. Needs of exploring the burden of recent onset seizures due to neurocysticercosis and challenges in southeast Asia focusing on scenario in Malaysia
Priyadarshi S. SAHU ; Sushela D. SOMANATH ; Yvonne A.L. LIM ; Rohela MAHMUD ; Chong T. TAN
Asian Pacific Journal of Tropical Medicine 2017;10(4):332-340
Seizures due to neurocysticercosis (NCC) is a neglected human-to-human transmitted disorder and an emerging problem worldwide. A substantial portion of recent onset seizures is known to be attributed to NCC in Taenia solium (T. solium) endemic areas where populations which neither raise pigs nor eat pig meat are also at risk. High prevalence of NCC causing epilepsy has been reported in the underdeveloped areas of Southeast Asia (SEA) however, only fragmentary information on its incidence is available in countries like Malaysia. In Malaysia T. solium infection was previously thought to be infrequent due to Muslim population majority and the religious prohibition of consuming pork, but it is not totally absent. There is an evident lack of knowledge and awareness of the actual burden, routes of transmission, and the impact of NCC in this region. The problem is assumed to be more prevalent particularly in cities because of the frequent inflow of possibly T. solium infected individuals or carriers among those who migrate from neighboring endemic countries to Malaysia. The issue of imported cases that are likely to be emerging in Malaysia is highlighted here. An accurate quantification of regional burdens of epilepsy due to NCC in Malaysia is warranted considering the disease emergence in its neighboring countries. It is suggested that the importance of NCC be recognized through quantification of its burden, and also to collect epidemiological data for its subsequent elimination in line of World Health Organization's mission for control of cysticercosis as a neglected tropical disease. In this review the need as well as a strategy for neuro-care center screening of epilepsy cases, and various issues with possible explanations are discussed. It is also proposed that NCC be declared as a reportable disease which is one of the eradicable public health problems in SEA.
5. Fatal case of amoebic liver abscess in a child
Khuen Foong NG ; Kah Kee TAN ; Romano NGUI ; Yvonne A.L. LIM ; Amirah AMIR ; Yamuna RAJOO ; Rohela MAHMUD ; Hamimah HASSAN
Asian Pacific Journal of Tropical Medicine 2015;8(10):878-880
We reported a case of amoebic liver abscess (ALA) in a 6-year-old Malaysian boy who presented with fever, lethargy, diarrhoea and right hypochondriac pain. On admission he was diagnosed with perforated acute appendicitis and a laparotomy was done. After surgery he developed acute respiratory distress. Ultrasonography, chest X-Ray and CT scan revealed two ALAs in the posterior segment of right lobe of liver, pleural effusion and collapsed consolidation of lungs bilaterally. Percutaneous liver abscesses drainage was done and intravenous Metronidazole was started. PCR carried out on the pus from the abscess was positive for Entamoeba histolytica. Patient however succumbed to the infection one week after admission.
6. Liver cirrhosis and splenomegaly associated with Schistosoma mansoni in a Sudanese woman in Malaysia: A case report
Yamuna RAJOO ; Rohela MAHMUD ; Yvonne A.L LIM ; Arine Fadzlun AHMAD ; Amirah AMIR ; Zurainee Mohamed NOR ; Romano NGUI ; Ng Rong XIANG ; Sharifah F.S. OMAR ; G KUMAR
Asian Pacific Journal of Tropical Medicine 2015;8(4):334-336
We report a case of a patient with Schistosoma mansoni infection who presented with liver cirrhosis and splenomegaly. She was diagnosed by a serological test and Kato-Katz thick smear stool examination. The patient was a 52-year-old woman from Sudan who came to Malaysia for a week to visit her sons. The patient lives in the middle of Rabak region, Sudan, a highly endemic area for schistosomiasis where her daily routine includes rearing of cows and farming. The site of toilet and sources of drinking water are canals and wells; both infested with snails. Patient had a long history of exposure and coming into contact with water from these canals and wells.