Basal cell nevus syndrome is a rare autosomal dominant disorder with a prevalence of between 1in 60,000 to 1in 120,000. This disorder is associated with a panoply of phenotypic that includes developmental anomalies and tumors particularly basal cell carcinoma. The genetic abnormality in almost all known cases is a mutation in the PATCHED] gene which is essential for normal body and limb patterning.? abnormalities We report a 50-year-old Filipina who suffered from multiple recurrent pigmented papules, plagues, nodules, and tumors on the face with the first tumor appearing at age 20.
Basal Cell Nevus Syndrome

Introduction: Psoriasis is a chronic autoimmune disease that affects the skin, nails, and musculoskeletal system. Musculoskel- etal involvement, called psoriatic arthritis occurs in 10-25% of patients with psoriasis and can lead to disability if left untreated. Early detection and intervention of psoriatic arthritis has been shown to decrease morbidity. The Psoriasis Epidemiology Screening Tool (PEST) may detect the presence of psoriatic arthritis and has been validated in differ- ent countries. Currently, there is no Filipino version. Objectives: To translate, adapt, and validate PEST in Filipino language. Methods: In the first part of the study, PEST was translated and culturally adapted into Filipino. It was pretested in 30 participants. Three experts then assessed its content and face validity. After the content and face validity were met, 115 participants an- swered the Filipino version of the PEST questionnaire. Results: The Filipino version of the PEST questionnaire was comprehensible, clear and appropriate. All questions were relevant. Some words were edited per expert recommendation. One hundred fifteen adult patients were asked to answer the question- naire. It showed good reliability at 94%. Conclusion The Filipino Version of the PEST was found to be reliable and valid. Larger samples to determine the tool’s applica- bility is recommended.
Psoriasis

Bullous pemphigoid (BP) is the most common autoimmune blistering disease primarily characterized by tense blisters and occasionally with urticarial plaques, affecting the skin and mucous membranes. These are caused by autoantibodies against BP180 and BP230 which target antigens on the basement membrane zone. The diagnosis relies on the integration of clinical, histopathological, immunopathological, and serological findings. The management depends on the clinical extent and severity. We present in this article a literature review and the clinical consensus guidelines of the Immunodermatology Subspecialty Core Group of the Philippine Dermatological Society in the management of BP.
Pemphigoid, Bullous