Introduction: Breast cancer is a contributing factor to women’s death. Mammography screening uptake is low in Islamic countries compared to non-Islamic countries. In Saudi Arabia, a first step is to develop an appropriate intervention at workplace to increase mammography screening rates, this review was conducted to update current knowledge on the effectiveness of existing workplace interventions to enhance mammography screening uptake in Saudi Arabia. Methods: A systematic review and narrative syntheses was conducted. All studies that assessed the effectiveness of workplace interventions to increase mammography screening uptake among female employees were included. This review was registered on PROSPERO with the number CRD42021281744. Results: Three studies were included. All the studies evaluated a workplace educational intervention aiming to increase mammography screening uptake. It was found that workplace-based interventions increase breast mammography screening uptake while the effectiveness of the existing workplace intervention remains questionable and further research is warranted to improve our understanding of how we can successfully improve mammography screening among women in Islamic countries. Conclusion: This review has demonstrated that the effectiveness of the existing workplace interventions to increase mammography screening uptake remains unclear. It was also found that no studies about workplace interventions in Islamic countries.