Objective To investigate epidemiologically the prevalence of obesity and overweight in Mongolian and Han residents aged over 55 years old in pastoral area of Inner Mongolia,China.Method From 2008 to 2009,with diagnostic criteria of overweight and obesity adopted by Chinese and World Health Organization (WHO),an epidemiological investigation was carried out in 9 146 subjects.Result The incidences of obesity and overweight in Mongolian and Han residents were 32.43％ (32.25％ by WHO criteria),19.09％ (9.91％),and 33.60％ (29.85％),15.19％ (7.66％),respectively.The prevalence of obesity in Mongolian residents was higher than that in Han residents (x2 =16.272,P＜0.01).The status of obesity in Mongolian and Han female residents was more marked than that in male residents (P ＜ 0.05).Overweight between male and female of Han population was different(x2 =5.541,P =0.019).The prevalence of obesity between Mongolian and Han was statistically different (x2 =16.272,P＜0.01).Waist circumference,waist/height ratio,and body mass index between Mongolian and Han were also different (all P ＜ 0.01).Conclusion Differences in prevalence of overweight and obesity were found between Mongolian and Han ethnics among residents aged over 55 in pastoral area of Inner Mongolia,China.

Alzheimer's disease is a neurodegenerative disease of the central nervous system. With the aging of the population, the prevalence of AD is increasing, which seriously affects the society and family. The etiology of AD is influenced by many factors, such as genetic factors and environmental factors. Among them, the influence of genetic factors accounted for dominant position. Therefore, the study of genetic factors plays an important role in the prevention and treatment of AD. In this paper, we reviewed the recent studies on genome-wide association study and rare variants of late-onset AD in different population.

Objective To understand the epidemiological characteristics and distribution of mild cognitive impairment (MCI) in elderly populations from Mongolian and Han nationalities living in the pastoral areas of Inner Mongolia Autonomous Region of China.Methods According to the MCI clinical diagnostic criteria from Diagnostic and Statistical Manual of Mental Disorders 4th revised edition (DSM-Ⅳ ) by American Psychiatric Association,the individuals under study were at the age of 55 or over,with Mongolian or Han ethnicities and living in the pastoral area of Inner Mongolia.Results The crude MCI morbidity rates of Mongolian and Han of the study populations in the pastoral area of Inner Mongolia Autonomous Region of China was 19.48％ (1782/9146)and the standardization morbidity was 18.98％.The crude MCI morbidity rates of both Mongolian and Han cthnicities were 17.46％ (the standardization morbidity was 16.99％) and 20.60％ (the standardization morbidity was 19.98％ ),respectively.There showed a significant positive correlation between the crude morbidities and age,also significantly increasing with the latter.In the Mongolian population,the morbidity increased from 12.17％ at the age 55-59 to 27.78％ at 85 while in the Han population,the morbidity increased from 15.50％ at the age 55-59 to 23.53％ at 85.In both the populations of Mongolian and Han,there was a statistically difference found between the morbidities of MCI ( x2=13.229,P=0.000).The morbidity was higher in Hans than in the Mongolians.However,there was no statistically significant difference noticed between the morbidities of MCI in the Mongolian males and females ( x 2 =2.376,P =0.123 ).There was statistically significant difference found between the morbidities of MCI in the Han males and females,with females having higher risk than males (x2=24.470,P=0.000).Conclusion The morbidity of MCI in the elderly Mongolian and Han populations from the pastoral area of Inner Mongolia Autonomous Region of China was considered to be quite high and correlated to age and gender.