Objective To develop the dual-beam technology of cyclotron to produce radioactive nuclide, which can increase radiopharmaceuticals output. Methods A new target is installed in cyclotron standby target, and at the same time the tubes and electronic components are fixed to produce radioactive nuclide through dual-beam technology, the product is tested by the dose calibrator. Results The radioactive nuclide can be produced through dual-beam technology and the output is nearly double times about which a single target. Conclusion The productions of cyclotron radioactive isotope are improved by dual-beam technology and meet the clinical needs of PET/CT examination for drugs.

Objective To study the diagnosis, management and prognosis of intracranial metastases of gestational trophoblastic tumour (GTT) patients who had emergency surgical decompression due to highly increased intracranial pressure. Methods Ninety-three patients with intracranial metastases of gestational trophoblastic tumour were hospitalized in our department of Peking Union Medical College Hospital from 1985 to 2004. Thirteen of them who underwent emergency craniotomy were retrospectively analyzed, and all of them presented with raised intracranial pressure and intracerebral haemorrhagic mass. Result Of the thirteen patients who underwent surgery in combination with multiagent systemic chemotherapy, seven achieved complete remission(CR), five had partial remission(PR), and one died of disease progression. Conclusions Emergency surgical treatment is the important method of choice for brain metastasis in patients displaying rapidly deteriorating signs. An undetermined intracranial haemorrhage in young female patients of reproductive age group should raise the suspicion of cerebral metastatic choriocarcinoma.