1.“While finding where the water leaks, you find smoke” - A case report: Incidental finding of moyamoya for a Filipino worked up for subarachnoid hemorrhage.
Christian Emmanuel T. Lim ; Maria Felicidad A. Soto ; Renato Carlos
Journal of the Philippine Medical Association 2018;96(2):69-73
Moyamoya Disease was initially reported in 1957 as vessels resembling a puff of smoke,
alongside hypoplasia of bilateral internal carotids. The true incidence remains elusive. Genetic
studies point to familial occurrence of the disease, however some studies refute this, claiming
that environmental factors are to blame. The treatment strategies remain an enigma, more so in
our country where data is scarce. We present a case of an asymptomatic Moyamoya disease
incidentally diagnosed in the work - up of Subarachnoid Hemorrhage. The basis of the
management is being provided.
Headache
2.Sedoanalgesia With Midazolam and Fentanyl Citrate Controls Probe Pain During Prostate Biopsy by Transrectal Ultrasound.
Fabio Hissachi TSUJI ; Renato Caretta CHAMBO ; Aparecido Donizeti AGOSTINHO ; Jose Carlos Souza TRINDADE FILHO ; Carlos Marcio Nobrega DE JESUS
Korean Journal of Urology 2014;55(2):106-111
PURPOSE: To assess the pain intensity of patients administered midazolam and fentanyl citrate before undergoing transrectal ultrasound-guided prostate biopsy. MATERIALS AND METHODS: This was a study in patients with different indications for prostate biopsy in whom 5 mg of midazolam and 50 microg of fentanyl citrate was administered intravenously 3 minutes before the procedure. After biopsy, pain was assessed by use of a visual analogue scale (VAS) in three stages: VAS 1, during probe introduction; VAS 2, during needle penetration into prostate tissue; and VAS 3, in the weeks following the exam. Pain intensity at these different times was tested with stratification by age, race, education, prostate volume, rebiopsy, and anxiety before biopsy. Pain was ranked according to the following scores: 0 (no pain), 1-3 (mild pain), 4-7 (moderate pain), and 8-10 (severe pain). Statistical analysis was performed by using Kruskal-Wallis and Wilcoxon two-tailed tests with a significance of 5%. RESULTS: Pain intensity was not influenced by any risk factors. The mean VAS 1 score was 1.95+/-1.98, the mean VAS 2 score was 2.73+/-2.55, and the mean VAS 3 score was 0.3+/-0.9, showing greater pain at the time of needle penetration than in other situations (VAS 2>VAS 1>VAS 3, p=0.0013, p=0.0001, respectively). Seventy-five percent of patients reported a VAS pain scale of less than 3.1 or mild pain. CONCLUSIONS: Intravenous sedation and analgesia with midazolam and fentanyl citrate is a good method for reducing pain caused by prostate biopsy, even during probe insertion.
Analgesia
;
Anesthesia and Analgesia
;
Anxiety
;
Biopsy*
;
Biopsy, Needle
;
Continental Population Groups
;
Education
;
Fentanyl*
;
Humans
;
Midazolam*
;
Needles
;
Pain Measurement
;
Prostate*
;
Risk Factors
;
Ultrasonography*
3.What Is the Ideal Core Number for Ultrasound-Guided Prostate Biopsy?.
Renato Caretta CHAMBO ; Fabio Hissachi TSUJI ; Flavio DE OLIVEIRA LIMA ; Hamilto Akihissa YAMAMOTO ; Carlos Marcio Nobrega DE JESUS
Korean Journal of Urology 2014;55(11):725-731
PURPOSE: We evaluated the utility of 10-, 12-, and 16-core prostate biopsies for detecting prostate cancer (PCa) and correlated the results with prostate-specific antigen (PSA) levels, prostate volumes, Gleason scores, and detection rates of high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP). MATERIALS AND METHODS: A prospective controlled study was conducted in 354 consecutive patients with various indications for prostate biopsy. Sixteen-core biopsy specimens were obtained from 351 patients. The first 10-core biopsy specimens were obtained bilaterally from the base, middle third, apex, medial, and latero-lateral regions. Afterward, six additional punctures were performed bilaterally in the areas more lateral to the base, middle third, and apex regions, yielding a total of 16-core biopsy specimens. The detection rate of carcinoma in the initial 10-core specimens was compared with that in the 12- and 16-core specimens. RESULTS: No significant differences in the cancer detection rate were found between the three biopsy protocols. PCa was found in 102 patients (29.06%) using the 10-core protocol, in 99 patients (28.21%) using the 12-core protocol, and in 107 patients (30.48%) using the 16-core protocol (p=0.798). The 10-, 12-, and 16-core protocols were compared with stratified PSA levels, stratified prostate volumes, Gleason scores, and detection rates of HGPIN and ASAP; no significant differences were found. CONCLUSIONS: Cancer positivity with the 10-core protocol was not significantly different from that with the 12- and 16-core protocols, which indicates that the 10-core protocol is acceptable for performing a first biopsy.
Adult
;
Aged
;
Cell Proliferation
;
Endosonography/*methods
;
Equipment Design
;
Follow-Up Studies
;
Humans
;
Image-Guided Biopsy/*instrumentation
;
Male
;
Middle Aged
;
Neoplasm Grading
;
Neoplasm Staging
;
Prospective Studies
;
Prostate/metabolism/pathology
;
Prostate-Specific Antigen/metabolism
;
Prostatic Intraepithelial Neoplasia/metabolism/*pathology
;
Prostatic Neoplasms/metabolism/*pathology
;
Rectum
;
Reproducibility of Results