1.Cost Reduction Effect Produced by Original SPD (Supply, Processing and Distribution) System
Tetsuya AKUTSU ; Yumiko ICHIMURA ; Takao SUGIYAMA ; Hiroshi SAWAHATA ; Syuhei SUZUKI
Journal of the Japanese Association of Rural Medicine 2003;52(4):762-765
As a management improvement tool useful for cost containment and adaptable to the trend of reform in recent years, we introduced the SPD system of medical materials. Since there had been no precedent for the introduction of the SPD system in the hospitals affiliated with Kouseiren and even for the dealer it was the first trial, an original system was built. The quantity of materials in stock was fixed by entrusting, so-called the shelf control system. This system has been left in charge of one hospital employee and one individual employed by the dealer.The condition at the time when this system was introduced was not to increase personnel but to lower costs. The maintenance costs of this system were as cheap as 137,700 yen per month on a five-year lease. As a result, the quantity of inventory at the time of the term-end settlement of accounts reduced by about 18 million yen. Moreover, in marked contrast with increased income, the amount of money expended in the purchase of medical materials decreased from that in the pervious year. Though the number of items used in each department has increased by 480 items now from the start, the inventory is 0 yen.This system is very useful especially for the inventory management of specific insurance medical materials, because it can take in insurance claim data on MO (Magneto Optical Disk), compare it with the purchase data of materials and check the income-and-expenditure balance of specific insurance medical materials immediately. The sum of the amount of temporary stock curtailment for the past two years and six months and the annual purchase curtailment amount was 93,380,000 yen.It is concluded that the introduction of the SPD system has contributed much to the improvement of inventory management.
Insurance
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System
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Reduction - action
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Effective
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Original
2.Conservative Treatment of Chronic Kidney Diseace (CKD)
Journal of the Japanese Association of Rural Medicine 2008;57(6):809-814
In Japan, the number of dialysis patients as of the end of fiscal 2007 has hit the 275,000 mark. The nation is now ahead of the rest of the world in the number of patients per million population. The largest problem that confronts us is that the enormous cost of dialysis is putting a great strain on the nation's finances. In addition, it should be mentioned that the quality of life of dialysis patients is aggravating. It is very rare for renal disease patients to receive kidney transplants, because only 200 kidneys are offered per year in Japan. So most of the patients have no choice but to depend on dialysis for the rest of their life.In the treatment of chronic kidney disease (CKD), it is important to for physicians to delay initiating dialysis as much as they can in Japan. In 1987, I began the programmed treatment of patients in a predialysis state with two nephrologists. The treatment is based on the “Toride guidelines for CKD”. There is an annual meeting of patients. Laboratory data and the history of medication are preserved in sheets.In the CKD clinic of our hospital, there are many devices for time-consuming. Full laboratory data apear quickly on the computer panel, and a clerk enters main data in patients, CKD records.The principles of the clinic iuclude control of office blood pressure and home blood pressure, mild restriction of protein intake, salt intake restriction, monitoring the diet from the data of 24 hours urine collection, control of hemoglobin concentration, serum bicarbonate and phosphate concentration. Reduction in urine protein excretion to less than 0.5 gram per day is done by dietary protein restriction, control of blood pressure and administration of angiotensin converting enzyme inhibitor or angiotensin receptor blocker.The outcomes of the Toride Cohort Study in the past 21 years are as follows:1. Reduction in medical cost by slowing the progression of CKD;2. Reduction in the dialysis-to-non dialysis rate;3. Appearance of the “arrested” or “remission” cases; and;4. Detection of the new risk factors for progression of CKD such as hyperphosphatenia and metabolic acidosis by multivariate analysis.There is a bare possibility open for a CKD patient to receive the “right” treatment of CKD, because only four to five clinics adopting the Toride guidelines are available in Japan.Physicians in CKD clinics have to judge and adjust many variables. The clinics spend plenty of time and effort on the treatment of CKD.In Japan, the medical fee in clinics is dependent on the number of visiting patients and on the number and quality of laboratory examinations, so the physicians keep away from CKD clinics.For the reduction of cost of dialysis, spread of “right” treatment is needed. For spread of the treatment, additional medical fee per patient visit is necessary as incentive.
Dialysis procedure
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therapeutic aspects
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Japan
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Reduction - action
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control
3.Studies on release behavior of sustained release tablets of extracts of Gardenia by antioxidant activity.
Yi-wang GUO ; Zhuang ZHAO ; Yan-ke CHENG ; Di WANG ; Shou-ying DU ; Yang LU
China Journal of Chinese Materia Medica 2014;39(17):3274-3277
Using sustained release tablets of gardenia extract as model drug and DPPH radical scavenging capacity as antioxidant index, the feasibility of using pharmacodynamics index was explored to evaluate sustained release tablets. Applying the established quantifiable method of DPPH radical scavenging to the dissolved liquid of model drug, release profiles and biological effects profiles were drawn, and their correlation was discussed. A good correlation was observed by linear regression and f2 actor, suggesting that the indicator could be used to evaluate sustained release tabletsofextracts of gardenia in which iridoids were mainly involved.
Antioxidants
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metabolism
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pharmacology
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Biphenyl Compounds
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metabolism
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Delayed-Action Preparations
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metabolism
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pharmacokinetics
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Free Radicals
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metabolism
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Gardenia
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chemistry
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Kinetics
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Linear Models
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Oxidation-Reduction
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drug effects
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Picrates
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metabolism
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Plant Extracts
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metabolism
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pharmacokinetics
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Tablets