No abstract available.
Red-Cell Aplasia, Pure*

No abstract available.
Red-Cell Aplasia, Pure* ; Rituximab*

Humans ; Red-Cell Aplasia, Pure

No abstract available.
Myelodysplastic Syndromes* ; Red-Cell Aplasia, Pure*

Thymoma, a rare epithelial neoplasm, is the most common anterior-superior mediastinal tumour. Thymoma can occur sporadically or in association with other conditions, such as myasthenia gravis, pure red cell aplasia (PRCA), and hypogammaglobulinemia. Only 5% of thymoma cases develop PRCA; however, 10–50% of patients presenting with PRCA have an associated spindle cell type thymoma. Thymoma complicated by PRCA is associated with a poor outcome. We report the case of a 38-year-old female who presented with chest pain, and was diagnosed with an anterior mediastinal mass. A thymectomy was performed, and histopathological examination revealed mixed thymoma; two months later, the patient developed PRCA. The present case reinforces the need for clinicians to be vigilant with thymoma patients, even following thymectomy.
Erythropoiesis ; Mediastinum ; Red-Cell Aplasia, Pure ; Thymoma

Consensus ; Humans ; Red-Cell Aplasia, Pure

The authors have described a case with pure red cell aplasia (P.R.C.A.) caused by the administration of diphenylhydantoin after head injury. P.R.C.A. associated with diphenylhydantoin is very rare and easily treated with a discontinuation of diphenylhydantoin & steroids.
Craniocerebral Trauma ; Phenytoin* ; Red-Cell Aplasia, Pure* ; Steroids

Humans ; Anemia, Aplastic/genetics* ; Red-Cell Aplasia, Pure ; Chromosome Disorders

Thymomas are associated with different paraneoplastic syndromes, with the most clinically important association being with myasthenia gravis, hypogammaglobulinemia, and pure red cell aplasia (PRCA). The optimal therapy for PRCA that complicates a thymoma is unknown, given the rarity of the clinical situation. It has been suggested that remission following surgery alone is uncommon and most patients will require some other form of therapy. We report a case of PRCA with a thymoma in a 59-year-old man who remained in complete remission of the PRCA after surgical resection of the thymoma.
Agammaglobulinemia ; Humans ; Middle Aged ; Myasthenia Gravis ; Paraneoplastic Syndromes ; Red-Cell Aplasia, Pure* ; Thymoma*

Pure red cell aplasia is a rare hematopoietic complication of drug-induced hepatitis, with only five cases reported worldwide. Moreover, pure red cell aplasia associated with autoimmune hemolytic anemia in the setting of drug-induced hepatitis is exceedingly rare. We recently experienced a case of drug-induced hepatitis complicated by pure red cell aplasia and autoimmune hemolytic anemia without parvovirus B19 infection. Here, we report the case and review the literature.
Anemia, Hemolytic, Autoimmune ; Drug-Induced Liver Injury ; Hepatitis ; Parvovirus ; Red-Cell Aplasia, Pure