1.Obesity among patients with schizophrenia, attending outpatient psychiatric clinic, Hospital Universiti Kebangsaan Malaysia
Salmi Razali ; Ainsah Omar ; Osman Che Bakar ; Shamsul Azman Shah
ASEAN Journal of Psychiatry 2007;8(2):90-96
Objective: This study aimed to determine the prevalence of obesity among patients with
schizophrenia and its association with the demographic profile. Methods: This is a cross
sectional study. Subjects were selected using systematic sampling. Patients attending the out
patient psychiatric clinic, Hospital Universiti Kebangsaan Malaysia, who fulfilled the criteria
and able to give consent were included in this study. Diagnosis of schizophrenia was made
using Structured Clinical Interview (SCID) for DSM-IV. Demographic profiles of the patients
were obtained and anthropometric measurements were measured and classified according to
Body Mass Index (BMI) and Waist Circumference (WC) of Asian population. Results: A total
of 97 patients were included. The prevalence of overweight (BMI: 23.0- 27.4 kg/m2) was
39.2% (n=38), and the prevalence of obesity (BMI: >27.0 kg/m2) was 35.1% (n=34). BMI
was higher among non-Chinese (Malay and Indian, p=.03) and those who had low total
household income (p=.03). Sixty-two patients (63.9%) had high WC, which was associated
with male (p=.003) and non-Chinese (p=.03). Conclusions: Obesity is highly prevalent among
patients with schizophrenia. The risk factors for obesity include male, non-Chinese and those
with low total income. The high WC among non-Chinese and male patients suggests that they
are at a higher risk of developing obesity-related physical illnesses. These findings support
that obesity is a common critical issue among schizophrenic patients, and it warrants serious
clinical interventions.
2.Anxiety and depression among patients before and after Percutaneous Coronary Intervention (PCI) at National Heart Institute(NHI)
Ho Siew Eng ; Syed Zulkifli Syed ; Lexshimi R.Gopal ; Hamidah Hassan ; Santhna Lecthmi ; Teoh Koi Hong ; Razali Omar ; Hanida Mokhtar
Medicine and Health 2007;2(1):26-33
Percutaneous coronary intervention (PCI) is an invasive diagnostic investigation that may result in high level of anxiety and "fear of the unknown" among cardiac patients. An increment of anxiety among PCI patients will augment the level of stress and this extreme stress level will then aggravate depression. The objective of this study was to determine the incidence of anxiety and depression before and after PCI. This was a cross-sectional descriptive study. The Hospital Anxiety and Depression Scale (HADS) was used. It measured two elements, namely the anxiety and depression levels of patients before and after PCI.This study was conducted in the cardiology wards Anggerik and Dahlia, and Day Care of the National Heart Institute, from January to February 2006. A sample of 61 patients before and after PCI who fulfilled the inclusion criteria were recruited in this study. Of these, 40 and 38 patients before and after PCI respectively , had low anxiety levels; while 47 and 46 patients before and after PCI had low depression levels.Anxiety and depression levels before and after PCI were not significantly correlated to socio demographic status. However a significant correlation (p<0.05) was found between anxiety and depression levels before and after PCI. The low levels of anxiety and depression seen among patients before and after PCI at National Heart Institute could possibly due to the adequate facilities and health education program provided by the physician, nurses and cardiac technician.
3.Identification of dietary patterns associated with characteristics of successful aging
Nik Nur Izzati Nik Mohd Fakhruddin ; Suzana Shahar ; Roslee Rajikan ; Mohd Azahadi Omar ; Normah Che Din ; Rosdinom Razali ; Sakinah Harith ; Hamid Jan Jan Mohamed ; Bibi Nabihah Abdul Hakim
Malaysian Journal of Nutrition 2019;25(1):47-57
Introduction: This study aimed to identify dietary patterns (DPs) and their association with successful aging (SA).
Methods: A comparative cross-sectional study was conducted among 579 elderly subjects recruited from four states in Malaysia through a multistage random sampling method. SA was defined as having no chronic illnesses, no functional limitation, normal global function, no depression, a good quality of life and good self-perceived health. Information on dietary intake was obtained using a diet history questionnaire. Cognitive functions were assessed using the Mini Mental State Examination (MMSE), depressive symptoms using Geriatric Depression Score-15 items (GDS-15) and a question regarding their perceived health and quality of life. Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) questionnaires were used to determine functional status. DPs were obtained using the principal component analysis (PCA) approach. An ordinal logistic regression model was used to examine associations between DP scores and SA.
Results: Five DPs were identified namely ‘sweet foods-beverages’, ‘meat-vegetablesrice and noodles’, ‘local snacks-fish and seafood-high salt foods’, ‘fruits-legumes’, and ‘tropical fruits-oats’. A higher score for ‘tropical fruits-oats’ DP was associated with SA [Adjusted OR=1.59 (95% CI: 1.08-2.32)]. However, the association diminished when the model was adjusted for education level. Further analysis indicated that this DP increased the chance of SA among those with secondary education and above [Adjusted OR=2.43 (95% CI: 1.09–5.42)].
Conclusion: Tropical fruits-oats’ DP is associated with SA among elderly with secondary education and above. There is a need to investigate DPs among those with lower education.
5.Effect of symbiotic bee fungus on survival of stingless bee Heterotrigona itama larvae
Nurul Izdihar Razali ; Nur Aliya Suhada Ahmad Nordin ; Nur Hannani Mohd Ridzuan ; Shamsul Bahri Abdul Razak ; Fatimah Hashim ; Mohd Nizam Lani ; Wan Bayani Wan Omar ; Ehsan Abdul Rahman ; Wahizatul Afzan Azmi
Malaysian Journal of Microbiology 2022;18(2):154-162
Aims:
Symbiotic bee fungus associated with the stingless bee larval food has been revealed to play a major role in performing a mutual relationship with the host. The fungus is believed capable to produce crucial nutrients that are required for larval pupation. However, detailed information on the fungus identification isolated from the larval food of our native Indo-Malaya stingless bee, Heterotrigona itama (Hymenoptera: Apidae), is poorly understood. Hence, this study was conducted to determine the effect of fungus isolated from the stingless bee larval food on the survival of H. itama larvae and identify the isolated fungus using both morphological and molecular analyses.
Methodology and results:
Elisa plates designed with F-bottom type were used as artificial brood cells in a controlled condition. The eggs transferred to Elisa plates were kept in the incubator with 75%-100% humidity and 25 ± 2.5 °C of temperature. This study carried out in three different treatments: (1) microbes-free larval food, (2) fresh larval food and (3) microbes-free larval food with fungus supplement. Results showed that the survival of H. itama larvae depends on the presence of beneficial fungus with the highest survival rate (Treatment 2 = 85.71%). The absence of the beneficial fungus in the fluid food of H. itama showed the lowest survival rate (Treatment 1 = 37.14%). Microscopy analysis showed that the fungus had various forms, including unconjugated asci, round-shaped ascospore and pseudohyphae. The molecular characterisation of the isolated fungi was performed using 23S rRNA gene sequencing using universal primers ITS1 and ITS4. DNA barcoding of three isolated fungi confirmed all isolated fungi matched Panus lecomtei (Basidiomycetes; Poriales; Polyporaceae) with 99.70% of similarity.
Conclusion, significance and impact of study
This study provides information on the importance of whitish fungus in appearance that existed in the brood cell, which is proposed to be the crucial component of in-vitro stingless bee queen rearing protocol.
Bees--microbiology