Objectives: To find out influencing factors of quality of life(QOL) of staffs in Centers for Disease Prevention and Control(CDC),whose results would be taken as theoretical evidence for government policy-makers to work out strategy of health human resources.Methods: The WHO Quality of Life Brief Scale(WHOQOL-BREF) was employed as the assessing tool for staffs of CDC who were in a city and its neighborhood counties.Each subject was asked to complete a spot self-assessment.Results: There is no significant difference of QOL of staffs between city and neighborhood county.Working at different departments was one of the influencing factors on psychological and social domains.Harmonious family relationship,good appetite,agreement to work competition,and confidence in working institutes were influencing factors to the total score of QOL.Conclusions: Scores of QOL of CDC staffs were relatively low with various influencing factors.It is necessary for leaders of related departments to take countermeasures to improve the QOL of CDC staffs.

The appearance and development of laser technology had made Raman spectroscopy one of the most attractive research fields in analysis using laser.Raman spectroscopy had been widely used in the analysis of material components and structure.In this review,recent advances of Raman spectroscopy on human blood were summarized,which including the basic research on red cells,white cells,platelets and the serum concentrations of various substances by Raman spectroscopy.The rewiew also intruduces the Raman spectroscopy on early diagnosis for cancer,diagnosis for blood diseases,and its future development.

To train the clinical ideation of students majoring in medicine is one of the goals of medical education. Applying the integrated teaching methods to the physiology theory education is helpful to cultivating students′abilities to think and practice the clinical ideation and application,inspiring their interests in study,evoking their ideation and enhancing their abilities to learn initiatively and solving problem independently.

The chemokine fractalkine primarily involves in chemotaxis,adherence and inflammation.Recently it has been discovered owning the ability of inhibiting cell death in neurons and glial cells,as well as protecting central nervous system from toxic damage.Fractalkine reduces the toxicity to neurons and glial cells mediated by excessive Fas L,glutamate(Glu) or lipopolysaccharide(LPS).In vivo neutralization of endogenous brain fractalkine signal pathway increases inflammatory cytokines secretion and neuronal cell death induced by LPS.Fractalkine may achieve its neuroprotective property through influencing expression of pro-apoptotic and anti-apoptotic proteins,intracellular Ca2+ level and inflammatory cytokines secretion via protein kinase B(PKB)/Akt and extracellular signal-regulated kinase(ERK)/MAPK pathways.

Fusion Proteins, bcr-abl ; genetics ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; complications ; genetics ; Male ; Middle Aged ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; etiology

AIM: To study the protective effects of Shenmai injection, a Chinese medicine, on angiotensin Ⅱ (AngⅡ)-induced rat cardiomyocyte apoptosis in vitro and the probable mechanism. METHODS: Cultured cardiomyocytes from neonatal rats were stimulated with AngⅡ. Cell viability were measured by MTT, and apoptosis was evaluated suing Hoethst33258 fluorescent dye staining and flow cytometry. Fluo-3/AM was used to test the change in intracellular free calcium. RESULTS: It was found that incubation with AngⅡ (10 -7 mol/L) for 48 h increased cardiomyocyte apoptosis, Shenmai injection (0 5 g/L, 1 0 g/L) inceased myocyte viability ( P

According to the changeover of modern medical teaching mode and the undergraduates' need of knowledge structure,we started the course Sociology of Sexuality in our university.In more than 3 years teaching experience and exploration,we arranged the content for each part of each chapter based on the teaching outline,teaching scheme and the students' knowledge and ability structure.As to teaching method,we adopted multimedia computer instruction,heuristic instruction,interactive instruction,participating teaching and audio-visual digital teaching method and so on.We are to introduce such a teaching means of exchange communication,and such an examination method combined with the traditional test as well as testing the capability of handling the actual problem,which can help to implementing the teaching work for Sociology of Sexuality.

Objective To study the effect of Bushen Tiaojing Chinese herbs on the expressions of endometrial integrin ?3 in infertile patients with polycystic ovary syndrome (PCOS) receiving ovulation induction therapies. Methods Thirty-six PCOS related infertility patients were divided into 2 groups at random, receiving different ovulation induction therapies:17 patients of group A were given clomephine citrate (CC)/human chorionic gonadotropin (hCG) therapies, and 19 patients of group B were given CC/ hCG combined with Chinese herbs therapies. 22 infertile women with fallopian tubal or male infactors were chosen as controls. The mRNA expressions of integrin ?3 in midluteal endometrium were measured by reverse transcription-polymerase chain reaction. Results Compared with controls, the expressions of endometrial integrin ?3 were weaker in group A (P0.05). Conclusion CC/hCG ovulation induction therapies may induce the decline of endometrium receptivity during midluteal phase, which Chinese herbs may promote.

The authors used a microvascular corrosion cast/scanning electron microscopy (SEM) technique to study the microvascular bed of the muscles of the medial pterygoid and masseter in two normal babies. The cast were prepared by perfusing the microvascular vessels with methyl methacrylate. Under SEM, the patterns of branches of the arteriole are: 1. tree like ramifications; 2. symmetrical branching; 3. fine plexiform branching. Moreover, the casts of arterial and venous vessels showed on their surfaces the typical imprint of the endothelial lining. Therefore, the venous vessels could be easily identified by the round nuclei of the endothelial cells of the venous vessels. On the other side, arteries and arterioles displayed spindle shaped nuclear imprints, oriented along the direction of the vessel. The morphological and functional characterization of the imprint of the precapillary sphincter and the two-grade anastomoses of the arcade arteries. The diameter of the capillary casts (mean?SE) was 5.6?1.9?m. Two or three capillaries join together to form a postcapillary venules, sometimes a single capillary reaches a major venous trunk was observed. These structural features were considered to play an important physiological role in the microcirculation in skeletal muscle.

Objective To investigate the changes and its significance of serum content of soluble CD40L(sCD40L) and C-reactive protein(CRP) in patients with acute cerebral infarction(ACI).Methods The content of serum sCD40L and CRP in 40 patients with ACI and 30 normal controls were measured by enzyme-linked immuno-sorbent assay and immunonphelometry.The content of serum sCD40L and CRP were compared in the patients of different pathogenetic condition and infarction size.The correlation between sCD40L and CRP and pathogenetic condition and infarction size were analysised.Results The contents of serum sCD40L and CRP in ACI group were significantly higher than normal control group(all P