1.Anaplastic Large Cell Lymphoma Presenting as a Soft
Siti-Aishah M.A. ; Salwati S. ; Idrus M. ; Rahimah R. ; Salmi A. ; Leong C.F. ; Sharifah N.A.
Medicine and Health 2008;3(1):69-74
Anaplastic large cell lymphoma (ALCL) is a rare tumour, accounting for approximately 3%
of adult non-Hodgkin lymphomas.1 Primary systemic ALCL frequently involves both lymph
nodes and extranodal sites. A 44-year-old woman presented with a firm, mobile mass in
the left iliac fossa region. Ultrasound findings showed a well defined inhomogenous soft
tissue mass, measuring 4x4x2.6cm in the deep subcutaneous region. Histopathological
examination revealed that the mass was infiltrated by large lymphoid cells with marked
nuclear atypia including kidney-shaped nuclei. These neoplastic cells expressed anaplastic lymphoma kinase (ALK) (both nuclear & cytoplasmic staining), CD30 and EMA but not for
T-cell (CD45RO and CD3), and B-cell (CD20 & CD79α) markers. Fluorescence in situ
hybridization (FISH) analysis showed a t(2;5)(p23;q35) chromosomal translocation.
Subsequently the patient developed shortness of the breath and a thoracic computed
tomography (CT) scan showed a mass encasing the right upper lobe bronchus. She also
had bilateral axillary lymph nodes, measuring 1 cm in diameter (biopsy was not done). The
mediastinum and endobronchial region did not show any abnormalities. She received 6
cycles of CHOP chemotherapy and remained disease free 2 years after diagnosis. ALCL,
rarely present as a soft tissue tumour and this disease should be included as a differential
diagnosis of any soft tissue mass.
2.Correlation Of FRAX Risk Score And Hip Fragility Fractures In Elderly Patients
Syed Ahmad Kabeer SJ ; Mohd Farid M ; Nur Atiqah MJ ; Zulaikha Z ; Mohammad Rostam S ; Ikhwan S ; Naim N ; Kuhanrajan R ; Syahril RA ; Kamarul Haqq AG ; Kamil MK
Malaysian Orthopaedic Journal 2018;12(Supplement A):237-
3.Anxiety Reaction in Children During Cast Removal using Oscillating Saw versus Cast Shear - A Randomised, Prospective Trial
Mohamed-Zain NA ; Jamil K ; Penafort R ; Singh A ; Ibrahim S ; Abdul-Rashid AH
Malaysian Orthopaedic Journal 2021;15(No.2):122-128
Introduction: To compare the anxiety levels demonstrated
by children during cast removal procedure between
oscillating saw vs cast shear methods.
Material and methods: A randomised prospective study of
102 children (mean age 8.3 ± 3.5 years) with fractures
involving upper or lower limbs. Children undergoing
removal of cast were divided into 2 groups; either by an
oscillating saw or a cast cutting shear. The level of anxiety
was assessed by recording the heart rate with a portable
fingertip pulse oximeter before, during and after removal of
the cast. Objective assessment was performed by
documenting the fear level on Children’s Fear Scale (CFS).
Results: There was a significant increase in the heart rate of
children during cast removal while using the oscillating saw
compared to cast shear (p<0.05). The noise level produced
by the saw exceeded 80 dB (mean 103.3 dB). The fear level
was significantly lower in the cast shear group (p<0.05).
Conclusion: The noise produced by the oscillating saw was
associated with an increased anxiety level in children
undergoing cast removal. Cast shear is a simple and
inexpensive instrument that can be used for cast removal in
overly anxious children.
4.Surgical Management of Distal Tibia Fracture: Towards An Outcome-based Treatment Algorithm
Rushdi I ; Che-Ahmad A ; Abdul-Ghani KAH ; Mohd-Rus R
Malaysian Orthopaedic Journal 2020;14(No.3):57-65
Introduction: Distal tibia fractures are frequently associated
with an extensive soft tissue injury which then leads to a
higher risk of complications such as infection, non-union and
eventually poor overall outcome. The purpose of this study is
to measure the outcome of distal tibia fractures treated with
internal fixation, external fixator or Ilizarov external
fixator(IEF). We aim to propose an algorithm for
management of distal tibia fractures by evaluating the
treatment options, outcomes and risk factors present.
Material and Methods: This study is a cross-sectional study
of all distal tibia fractures treated surgically in Tengku
Ampuan Rahimah Hospital, Klang from 1st January 2016 till
30th June 2018. Patient records were reviewed to analyse the
outcomes of surgical treatment and risk factors associated
with it.
Results: Ninety-one patients were included with a mean age
of 41.5 years (SD = 16.4). Thirty-nine cases (42.9%) were
open fractures. Thirty-eight patients (41.8%) were treated
with internal fixation, 27 patients (29.7%) were treated with
IEF and 26 patients (28.6%) were treated with an external
fixator. Among open fractures cases, no significant finding
can be concluded when comparing each surgical option and
its outcome, although one option was seen better than the
other in a particular outcome. Initial skeletal traction or
temporary spanning external fixator in close fractures
reduced the risk of mal-alignment (p value=0.001). Internal
fixation is seen superior to IEF and external fixator in close
fractures in term of articular surface reduction (p value =
0.043) and risk of mal-alignment (p value = 0.007).
Conclusion: There is no single method of fixation that is
ideal for all pilon fractures and suitable for all patients. This
proposed algorithm can help surgeons in deciding treatment
strategies in the challenging management of distal tibia
fractures to reduce associated complications.