No abstract available.
Rabies*

80% subjects among 50 bitten by dogs/cats were fully injected 4-6 doses of rabies vaccine. By ELISA (platelia Rage kit of Diagnostic Pasteur), we found that 42.5% of serum samples taken after injection 4 doses of rabies vaccine have titer 0.5IU/ml, it met WHO's minimum requirement. The GMT was 2.71 EU/ml. 62.5% of serum samples taken after injection 6 doses of rabies vaccine have titer 0.5IU/ml. The GMT was 3.14UE/ml.
Vaccines ; Rabies

This is a study on establishing the National References for inactivated rabies vaccine for human produced in ViÖt Nam. The results showed that the ViÖt Nam National References for Rabies Vaccine met the requirements of WHO
Vaccines ; Rabies

Rabies virus

Objectives: To determine the knowledge, attitude, and practices (KAP) on rabies prevention and control among primary care providers of children 0-18 years old. Methodology: This is an analytical cross-sectional study conducted among primary care providers of children 0- 18-years old in Barangay Sambag I, Cebu City, Philippines. A questionnaire to determine the KAP on rabies prevention and control, originally developed by Lañada et al., was modified and contextualized to the local setting. Respondents with at least 75% correct answers per domain were considered to have good overall knowledge, attitude, and practices. Furthermore, each question under the above domains was analyzed separately to determine any gaps in KAP. Results were recorded as frequencies and percentages. The association of KAP to one another and the respondents’ profiles were analyzed using Chi-square test with a level of significance of 0.05. Results: Among 285 respondents, 59.3% had poor knowledge, 35.8% had wrong practices, and 21.8% had negative attitude on rabies prevention and control. We found that 92.6% did not know that rabies is incurable. As to practices, performing “tandok” (42.5%), or the act of removal of rabies from a wound by using an animal horn, and applying herbal medicines (34%) were still done. Use of dog restraint (44.6%) and euthanasia (40%) weren’t favorable to study participants. Surprisingly, non-dog owners had good knowledge and positive attitude than dog owners. Conclusion Our study showed that majority of the study population had poor knowledge on rabies prevention and control, on disease transmission, and on the incurability of rabies. While majority had a positive attitude and correct practices, the unacceptability on the use of a dog restraint and euthanasia, especially among dog owners, were still evident.
Rabies ; Knowledge

Standard lyophylized rabid vaccine produced from CVS strain of Biopharma-Indonesia has met the criterion in terms of sterility, safety, efficacy (14.24 IU/ml), thermo-stability 37oC/month (5.4 IU/ml) and residual humidity (3.34%). Immune responsivity of the standard sample vaccine was determined by neutralizing method reaching 1/5 = 3.8 IU/ml; 1/25 = 1.7 IU/ml and 1/125 = 0.7 IU/ml
Rabies Vaccines ; Vaccines ; immunization

A purified rabie vaccine was prepared from mouse brain of CVS/P II from the Institute Bipharma-Indonesia. After refrigerating centrifuged, the vaccine was more pure and more efficacy. The sterility, innocuity and potency were perfect
Rabies Vaccines ; Vaccines ; immunization

After the use of improved purification procedure, the quality of 10 lots of rabie antiserum (IVAC) were assessed. Average potency reached > 200 IU/ml, the protein content was 57.85 mg/ml
Rabies ; serum ; proteins

The mortality rate due to rabies/100.000 inhabitants in Viet Nam was 0,43 during 1991-1995, was the highest mortality among 10 epidemic infectious diseases. From 1996-2000, some active interventive solutions had been implemented such as establishing the steering committee for rabies control; strengthening the role of the authority and co-ordination of ministries and sectors, promoting propaganda, education, training and building the special network; enhancing the quality of treatment and prevention for people who had been beaten by mad animals and suspected mad animals. As a result during 1996-2000 the mortality caused by bites of mad animals throughout the country reduced by more than 65% compared with 1991-1995. In some key provinces the mortality cause by bites of mad animals decreased 80-95%
Rabies ; Prevention & control

Study on the use of caprylic acid in the purification of anti rabies serum. The use of coprylic acid (octanoic) in the cleaning process IgG from horse plasma was studied to apply in the purification of anti rabies serum in the Institute of Vaccine and Biological Substances. When using caprylic acid in the purification of serum, the quality and quantity of the products were improved. The purity and colour of product was managed as desire. The process had a high effectiveness and short time of purification
Caprylic acid ; Rabies