1.STUDIES ON PHYSICAL LOCOMOTION PURSUIT ANALYZER, UTILIZING ELECTRICAL ENGINEERING
SHOICHI NAKANO ; SUKETSUNE IWAGAKI ; YOSHITAKA YAMANAMI ; TOSHIO SAKAI ; KIYOSHI SAITO ; RYUSUKE SHIMIZU
Japanese Journal of Physical Fitness and Sports Medicine 1971;20(1):14-23
In the studies of physical motion analysis the multiple photographic method with a stroboscope or the fast motion picture which has been used, are not sufficient to pursue a motion of some kinds of sports and of some hidden physical spot only from one direction and difficult to synchronize picture obtaind from three direction.
To make use of electrical engineering from the points of Physiology and Kinesiology, it is worthy of pursuing a physical motion on three dimensions, up & down, right & left and before & behind at once, and furthermore, physiological phenomena in electrocardiogram and electromyogram with connection to the above analyzer.
For that purpose a physical locomotion pursuit analyzer (SN-type, refered to PLPA later on) was devised.
The present devised analyzer is composed of a three dimensions-accelerometor in a gyroscope, a preamplifier, a integration amplifier and a pen-writing recorder.
As already known in the principle of physics, velocity can be obtained by single integration of acceleration rate and displacement by double integration of a acceleration rate.
In above the PLPA, therefore, acceleration rate, velocity and displacement, each of three dimensions can be determined. Capacity of the present analyzer was as follows; Frequency rate : 1.5-20.0 HZ (Static accelerated component under 1.5 HZ was cut by differentiation circuit of DC-cut), time constant of electrical integration circuit : about 0.2sec.
In the present report the outline of PLPA and some data of our experiments obtained by use of it were dealt.
The problems of the telemetering system of this analyzer and digital exhibition by connection to computer require further study.
2.URINARY PROTEIN AND ITS ELECTROPHORETIC PATTERN IN SOCCER PLAYERS
SHOICHI NAKANO ; SUKETSUNE IWAGAKI ; KUNIHIKO HARADA ; RYOSUKE SAKAI ; RYUSUKE SHIMIZU ; TOSHIO SAKAI
Japanese Journal of Physical Fitness and Sports Medicine 1971;20(4):200-209
Since manifestation of exercise proteinuria was reported by Leube (1878), the nature of exercise urinary protein has been extensively studied. The physiological mechanisms of increased excretion of urinary protein during and after exercise still remain to be obscured. The investigation presented here, were performed for the purpose of knowing the decreasing rate of soccer players body weight in each position during the soccer game, which was considered as a prolonged heavy exercise, of identifing the excretion of exercise proteinuria after performance of the game, and of studying the relation among urinary total protein at that time and its fraction in disc-electrophoresis.
The protein fractions of urine by disc-electrophoresis, compared with serum, manifested slight albumin fraction at rest, but it much increased after the game, and furthermore α1-, α2-globulin, transf errin and γ-globulin were observed.
The decreasing rate of body weight, total protein level and its albumin fraction mutually have the parallel relationship. Urine albumin fraction could have a relation to the decrease of body weight of athlete in each position rather than total protein.
These results mentioned above would suggest the exsistence of some relationship between the total volume of exercise and excretion of urine protein, especially albumin.
3.Impact of adaptive radiotherapy on survival in locally advanced nasopharyngeal carcinoma treated with concurrent chemoradiotherapy
Yusuke UCHINAMI ; Koichi YASUDA ; Hideki MINATOGAWA ; Yasuhiro DEKURA ; Noboru NISHIKAWA ; Rumiko KINOSHITA ; Kentaro NISHIOKA ; Norio KATOH ; Takashi MORI ; Manami OTSUKA ; Naoki MIYAMOTO ; Ryusuke SUZUKI ; Keiji KOBASHI ; Yasushi SHIMIZU ; Jun TAGUCHI ; Nayuta TSUSHIMA ; Satoshi KANO ; Akihiro HOMMA ; Hidefumi AOYAMA
Radiation Oncology Journal 2024;42(1):74-82
Purpose:
To investigate the clinical significance of adaptive radiotherapy (ART) in locally advanced nasopharyngeal carcinoma treated with intensity-modulated radiotherapy (IMRT).
Materials and Methods:
Eligible patients were treated with concurrent chemoradiotherapy using IMRT. Planning computed tomography in ART was performed during radiotherapy, and replanning was performed. Since ART was started in May 2011 (ART group), patients who were treated without ART up to April 2011 (non-ART group) were used as the historical control. The Kaplan-Meier method was used to calculate overall survival (OS), locoregional recurrence-free survival (LRFS), progression-free survival (PFS), and distant metastasis-free survival (DMFS). LRFS for the primary tumor (LRFS_P) and regional lymph node (LRFS_LN) were also studied for more detailed analysis. Statistical significance was evaluated using the log-rank test for survival.
Results:
The ART group tended to have higher radiation doses. The median follow-up period was 127 months (range, 10 to 211 months) in the non-ART group and 61.5 months (range, 5 to 129 months) in the ART group. Compared to the non-ART group, the ART group showed significantly higher 5-year PFS (53.8% vs. 81.3%, p = 0.015) and LRFS (61.2% vs. 85.3%, p = 0.024), but not OS (80.7% vs. 80.8%, p = 0.941) and DMFS (84.6% vs. 92.7%, p = 0.255). Five-year LRFS_P was higher in the ART group (61.3% vs. 90.6%, p = 0.005), but LRFS_LN did not show a significant difference (91.9% vs. 96.2%, p = 0.541).
Conclusion
Although there were differences in the patient backgrounds between the two groups, this study suggests the potential effectiveness of ART in improving locoregional control, especially in the primary tumor.