Objective To explore the effect of nursing clinical pathway in percutaneous coronary intervention(PCI)for patients with acute myocardial infarction(AMI).Methods Sixty AMI patients were randomly divided into nursing clinical pathway(NCP) group and control group equally by their registration sequence.Patients in the control group received routine nursing care,while patients in NCP group received nursing according to the nursing clinical pathway.Results Compared with the conventional group, the time of preoperative preparation,bed rest and hospitalization was obviously shortened.The incidence of complications and hospital costs were both declined,and meanwhile the quality of care and patient satisfaction improved significantly(P<0.05). Conclusions The application of nursing clinical pathway in patients with AMI can be timely and effective in the treatment of PCI, lower the mortality and complications and moreover improve nurses' working enthusiasm.