Objective To investigate the effects,difficult points and technical key points of the interventional embolization in brain micro-aneurysms.Methods Retrospectively analyzed the material of the interventional embolization in 38 patients with brain micro-aneurysm.Results Twenty-six cases were treated with simple spring coil embolization technology,4 cases were treated with double micro-catheter embolization technic,2 cases were treated with embolization combining ballon assistive technic and 6 cases were treated with embolization combining stent assistive technic.All the 38 patients successfully embolized.The postoperative immediate cerebral angiogram to determine the degree of embolization:12 cases were 0 level,21 cases were 1 level and 5 cases were 2 level.The Rankin grade results showed that 0-1 score in 24 cases,2 scores in 10 cases,3-4 scores in 2 cases and 5 scores in 2 cases.Thirty-three patients were followed up for 6-12 months.No aneurysms recurred or re-raptured.Conclusions The spring coil embolization of brain micro-aneurysms is a feasible,safe and effective method,though the technics involved is difficulty.Selecting suitable embolization technics according to the characteristic of each micro-aneurysm can reduce the risk of operation,decrease complications and increase the successful rate.