1.Clinical observation on obstructive sleep apnea-hypopnea syndrome cases in snoring children
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2010;(3):111-113
Objective:To explore the necessity of monitoring polysomnography (PSG ) in snoring children.Method:The PSG were monitored in 162 children with snoring or apnea.Acording to results of PSG,162 cases were separated into two groups:group obstructive sleep apnea hypopnea syndrome(OSAHS) and group primary snoring(PS),monitoring data including:apnea hypopnea index(AHI),snoring index(SI),lowest oxygen saturation(LSaO_2) and time of SaO_2<0.9,all data were undertaked statistical analysis. Result:In all 162 snoring cases,150 cases(92.6%) belong to group OSAHS,12 cases(7.4%) belong to group PS;Differences of data of age,sex and body mass index(BMI) are not significant but that of AHI,SI,LSaO_2 and time of SaO_2<0.9 are significant(P<0.05).Conclusion:It's necessary to monitor PSG in snoring children for early diagnosis and correct treatment to avoid disadvantage of OSAHS.
2.Study on Equilibrium Solubility of Aesculin and Its Apparent Oil/Water Partition Coefficient
China Pharmacy 2007;0(29):-
OBJECTIVE: To study the equilibrium solubility of aesculin and its apparent oil/water partition coefficient,and to provide basis for absorption mechanism study.METHODS: Equilibrium solubility of aesculin at the pH of 1.2~8.0 was determined by saturation method.The apparent oil/water partition coefficients of aesculin were determined by shaking flask method.RESULTS: The equilibrium solubility of aesculin at the pH of 1.2~6.8 was fluctuated slightly;it increased rapidly at the pH of 7.4;the maximum equilibrium solubility of aesculin was obtained at the pH of 8.0(10.58 g?L-1).The oil/water partition coefficient of aesculin changed slowly at the pH of 1.2~6.0;it decreased significantly at the pH of 6.0;the minimum oil/water partition coefficient was obtained at the pH of 8.0(0.03).CONCLUSIONS: The equilibrium solubility of aesculin and its apparent oil/water partition coefficient are associated with the pH of medium.The reason that aesculin has no effect on uric acid after oral administration is relevant to poor gastrointestinal tract absorption ability.
3.Process of neovascularization in mediating regulation of parathyroid hormone on metabolism of target organs
Chinese Journal of Endocrinology and Metabolism 2017;33(4):351-354
Neovascularization plays an essential role in the process of renovation in tissue damage,tumor growth, and hormones action. Parathyroid hormone (PTH) is one of the basic hormones that regulate the serum calcium, phosphorus, and bone metabolism. In recent years, studies involving the neovascularization-mediated effects of PTH on metabolism are becoming more and more popular and wider. Based on recent researches, the purpose of this paper is to summarize the changes of angiogenesis while PTH interacts with its target organs, especially interacts with osseous tissue.
4.The Application value of Multi-position Radiography in the Diagnosis for Fracture of Rib
Chinese Journal of Primary Medicine and Pharmacy 2010;17(9):1190-1191
Objective To discuss the application value of multi- position radiography in the diagnosis for fracture of rib.Methods 98 cases with integrated data of thoracic trauma undergone multi- position view X-ray from 2007 to 2009 were retrospectively reviewed.Results The percent of fractures with orthophoria view is 65.4%.The percents of fractures with oblique position,tangential projection and spot film under the X-ray fluoroscopy are 20.6%、5.1% 、8.8%,while doesn' t find the A-P position,The total percent is 34.6%.Conclusion Multi-position radiography can elevate the diagnosis for fracture of rib and has application value.
6.Concurrent chronic obstructive pulmonary disease in the acute phase gram-negative bacterium monitoring.
Hua YI ; Xiao-Ling FU ; Qun JIANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(8):613-614
Aged
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Aged, 80 and over
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Anthracosis
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complications
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microbiology
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Drug Resistance, Bacterial
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Gram-Negative Bacteria
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isolation & purification
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Gram-Negative Bacterial Infections
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complications
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Humans
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Male
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Middle Aged
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Pulmonary Disease, Chronic Obstructive
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etiology
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microbiology
8.Urinary Trypsinogen Activation Peptide (TAP) levels in the patients with acute pancreatitis
Qun QIAN ; Congqing JIANG ; Lifang FAN
Journal of Clinical Surgery 1999;0(05):-
Objective To explore the changes of urinary Trypsinogen Activation Peptide (TAP) levels in patients with acute pancreatitis (AP).Methods We observed the association between urinary TAP concentration and severity of acute pancreatitis with competitive enzyme-linked immunosorbent assay(ELISA). Urine samples were collected for TAP concentration at admission,24,48,and 72 h from 57 patients with AP who presented within 48 h of the onset of symptoms and from 11 control patients. Results The median urinary TAP at admission for severe acute pancreatitis(SAP) (98 nmol/L) was signficantly higher than the median for both mild pancreatitis (22 nmol/L,P0.05).The peak median urinary TAP in severe eroup was seen at admission.In the following days,TAP concentrations decreased graduallg.Conclusion Breakthrough activation of trypsinogen in pancreatic interstitial and blood may be the key event in the development of SAP.
9.Efficacy of sublingual immunotherapy in children with perennial allergic rhinitis
Lisheng XIE ; Yinzhu JIANG ; Qun HUANG
Chongqing Medicine 2013;(30):3622-3623,3625
Objective To observe the efficacy of the sublingual immunotherapy in children with perennial allergic rhinitis caused by mites .Methods A total of 61 pediatric patients with perennial allergic rhinitis caused by mite in otorhinolaryngology clinic were collected .The children were randomized into two groups :27 cases were divided into sublingual dust mite drops group(group A) , and 34 cases were divided into conventional treatment group (group B) .The symptom scores and sign scores of allergic rhinitis were observed after 6 months ,1 year and 2 years of treatment .Both the efficacy at the end of treatment and the rate of recurrence following 2 years were compared between the two groups .Results After six month of treatment ,the symptom scores in group A was reduced to (3 .70 ± 1 .54)scores ,higher than group B(2 .82 ± 1 .40)scores ,while sign scores in group A was reduced to (1 .19 ± 0 .68)scores ,having no statistically significance compared with group B ,Both symptom scores and sign scores were not changed sig-nificantly after 1 and 2 years of treatment .The efficacy evaluation was 74 .07% in group A ,and 82 .35% in group B .The difference had no statistical difference .The recurrence rate in group A was 29 .63% following 2 years after terminal treatment ,and was superi-or to those in group B (94 .12% ) ,with significant difference(P<0 .01) .Conclusion Dust mite drops sublingual immunotherapy is effective measures for the treatment of children with allergic rhinitis caused by mites .
10.The monitor report of Kashin-Beck Disease prevalence ra te in Changdu of Tibet
Jiang, LI ; Zhen-Qun-Pei, DING
Chinese Journal of Endemiology 2001;20(2):130-131
Objective To monitor KBD prevalence rate in Changdu of Tibet.Methods The aged 7~12 year children are tested with X- ray and epidemiological investigation.Results Xizang are still high yet,the 3 of 4 porints X-rates are more than 20% and the highest one is 55.34%.Conclusions The Changdu is the severest point of KBD in our country.