1.A Study on the Mental Health of Impoverished Students in Colleges from Training School to Regular College and its Inference Factors
Chinese Journal of Medical Education Research 2006;0(10):-
Objective:To investigate the mental health status of impoverished students and its inference factors;Methods:138 impoverished students were investigated by SCL-90,Juvenile Life Affairs Inventory and Social Support Scale;Result:①22.5% of impoverished students obviously have mental healthy problems.②Life affairs and social support had significant correlations with mental health.③Learning pressures,subjective support and other pressures could predict one's mental health rightly.Conclusion:It is serious for the mental health status of impoverished students,which can be influenced negatively by life affairs and positively by social support.
2.Application of artificial humeral head prosthesis in the treatment of proximal humerus bone tumor
Jun LIU ; Quanming LIAO ; Zhigui WANG ; Kejun WANG
Clinical Medicine of China 2011;27(2):185-187
Objective To evaluate the clinical effects of the artificial humeral head prosthesis in the treatment of proximal humerus bone tumors. Methods Fifteen patients with proximal humerus bone tumor had excision of bone tumor and application of artificial humeral head prosthesis were analyzed retrospectively. Among them,8 patients had osteosarcoma,4 patients had giant cell tumor of bone,2 patients had chondrosarcoma, 1 patient had fibrosarcoma. Results All cases were followed up for average (39 ± 5 ) months after the surgery.The duration time of operation were( 110 ± 10) minutes in average. The bleeding volume during operation were (600 ± 41 ) ml in average. One patient with osteosarcoma died of recurrence and metastasis 20 months after the surgery. The functions of the other 14 patients were assessed by Enneking system and the average score was 23.3 ± 3.7. The overall rate of excellent or good results was 84.6% ( 11/15 ). Conclusion Limb salvage surgery with the artificial humeral head prosthesis is an efficacious treatment for proximal humerus bone tumors,which can improve short-term clinical outcome.
3.Study on correlation between helicobacter pylori infection-associated gastritis and the apoptotic genes in gastric mucosa
Chunhui LAN ; Bosheng NI ; Hui CHANG ; Qianfei ZUO ; Shengtao LIAO ; Quanming ZOU ; Dongfeng CHEN
Chongqing Medicine 2014;(29):3858-3860
Objective To investigate the correlation between Helicobacter pylori (HP) infection-associated gastritis and the ap-optotic genes in gastric mucosa .Methods Forty-five patients with chronic gastritis were registrated in our study from November 2013 to December 2014 .HP infection status in the patients was detected by using urease test and 13C-urea breath test .The degree of gastritis in the gastric mucosa with HP infection was confirmed via histopathology .qRT-PCR was used to measure the mRNA ex-pressions of Bax ,Bak and Bcl-2 in the gastric mucosa with HP infection and matched normal gastric mucosa .Person analysis was used to assess the correlation between the HP infection-associated gastritis and the mRNA expressions of Bax ,Bak and Bcl-2 in the gastric mucosa .Results Forty-five patients with HP infection in antrum and 45 patients (100% ) with chronic antrum gastritis were identified ,including 28 patients (62 .2% ) with light gastritis ,16 patients (35 .6% ) with moderate gastritis ,1 patient (2 .0% ) with severe gastritis .9 patients (20 .0% )with metaplasia ,5 patients(11 .1% ) with low grade intraepithelial neoplasms .The urease tests were negative in the gastric body of 45 patients ,6 patients (13 .3% )were mild chronic gastritis in the body ;Patient with meta-plasia and intrapithelial gastritis was not found .The Bax expression in the HP-infected gastric mucosa was markedly increased when compared with the normal gastric mucosa (P< 0 .01) ,and positively correlated with the degree of gastritis (P< 0 .01) , whereas the expressions of Bak and Bcl-2 have no significantly deferences bttween two groups(P>0 .05) .Conclusion HP infec-tion-associated gastritis positively correlated with the expressions of apoptotic genes in gastric mucosa ,suggesting that HP infection might result in increasing the Bax expression and further enhancing the cell apoptosis .