Objective To evaluate the safety and efficacy of laparoscopy-assisted gastrectomy (LAG) for advanced gastric cancer.Methods The clinical data were retrospectively analyzed in 108 patients undergoing radical LAG for advanced gastric cancer from March 2008 to November 2011.Results 98 out of 108 patients were followed-up,the follow-up rate was 90.7％,with medium follow-up period of 30 months (range 6-70 months).26 patients died and 3 patients developed recurrence during the follow-up period.The overall recurrence rate was 26.9％ (29/108),in which the recurrence rate was 0 for Ⅰ B cases,18.8％ (6/32) for ⅡA,30％ (6/20) for ⅡB,30.8％ (8/26) for ⅢA,and37.5％ (9/24) for ⅢB,respectively.The overall 1,2,3-year survival rates were 95.4％,88.9％,73.8％,and 1,2,3-year progression free survival rates were 93.5％,83.3％,73.8％,respectively.Conclusions Compared with open gastrectomy LAG is a safe and feasible surgical procedure with satisfactory 3-year survival in patients of advanced gastric carcinoma.

Child ; Continuous Positive Airway Pressure ; Humans ; Pediatrics

Allostasis ; physiology ; Chronic Disease ; General Adaptation Syndrome ; physiopathology ; Humans ; Stress, Psychological ; physiopathology

Objective To explore the dispassed reason of Anhui provincial health senior titles evaluation.Methods The senior professional titles of the year 2009-2011 assessment results which were announced by the office of personnel titles of Anhui Provincial Health Department and the recorded results of the jury assessment were analyzed.Results In Anhui Province from 2009 to 2011 for three years,a total of 4 523 people participated in the senior title review by staff 3 039 people,by the proportion of 67.2％.2009,2010,2011 pass rate was 69.14％,66.85％,65.89％,respectively.1 484 people did not pass,and the rate was 32.8％.The main reason was the lack of reporting by professional and technical proficiency,non-standard format of application materials,assessment reporting material falsification.Conclusion Increasing the professional title appraisal policy propaganda,assessment focus which should be focused,the RAE quantitative score standards of health senior professional title,the establishment of a senior title of the series of health reporting assessment information system can improve this conditions.

Objective: To investigate the rural middle school students' mental health and explore its determinants. Methods: 989 rural middle school students in Jiangxi province were investigated with SCL-90, Social Support Rating Scale and the Chinese versions of EMBU. Results: The major problem of mental health were interpersonal sensitivity, obsessive-compulsive, depression, hostility and paranoid ideation. There was remarkable difference between boys and girls, senior and junior high school students. Multiple regression analysis indicated that the major determinants of the rural middle school students' mental health were subjective social support, usage of social support, father's and mother's rejection and denying, father's over-protection, mother's punishment and rigidity, different sex, grades and only children or non-only children. Conclusion: The students in rural middle school, especially in senior high school, had severe mental health problems, social support and parental rearing patterns have a significant influence on mental health.

Objective To evaluate the significance of combined determination of glutamic acid decarboxylase antibodies(GADA),islet cell antibodies(ICA) and insulin autoantibodies (IAA) in predictive of type 1 diabetes mellitus Methods GADA, ICA and IAA were determined by enzyme linked immunosorbent assay and C peptide by radioimmunoassay Diagnose efficiency were calculated by matrix decision method Results The positive rate of GADA,ICA and IAA(68 8%,43 0% and 39 8%) were significantly elevated in the patients with type 1 diabetes mellitus compared with type 2 diabetes mellitus or normal subjects ( P

[Objective] To observe the effect of Puji Xiaodu Decoction (PXD) on immune function in mice. [Methods] Thirty NIH mice were randomized into three groups. Group A was treated with normal saline, group B with 2.9 g/kg PXD and group C with 11.6 g/kg PXD for 7 days. After treatment, interleukin 2 (IL-2) production and natural killer cell (NK) activity in splenocytes and lymphocyte proliferation in the spleen were detected. [Results] PXD increased the NK activity and IL-2 production, and promoted the proliferation of splenic lymphocyte, the difference being significant as compared with group A ( P

AIM: To observe the changes of plasma content of Glu-plasminogen (plasmin, Pln) in patients during blood coagulation and/or fibrinolytic system activation. METHODS: Using specific McAb to antigenic determinant in NH 2 terminal (1-65 aa) of Pln and specific McAb to antigenic determinant in heavy chain of plasminogen, the sandwiched ELISA method was established to detect Glu-plasminogen and total plasminogen in human plasma collected from 220 normal controls and 40 patients after heart surgery. RESULTS: The average total plasminogen was (231.8?62.1) mg/L and average Glu-plasminogen was (231.9?45.8) mg/L in 220 normal controls, the ratio of Glu-plasminogen to total plasminogen (G/P) was 0.91. The ratio of Glu-plasminogen [(152.4?68.1) mg/L] to total plasminogen [(268.9?73.3) mg/L] in 40 patients after heart surgery was significantly lower than that in normal controls ( P

Objective To explore the value of echocardiography in patients with aortic stenosis who underwent transapical aortic valve implantation (TAAVI).Methods Fifteen high-risk patients with severe aortic stenosis were chosen in the present study,all of which received TAAVI in Fuwai Hospital Chinese Academy of Medical Sciences from June 2014 to March 2015.The left ventricular end-diastolic diameter (LVEDD),left atrial diameter (LAD),left ventricular ejection fraction (LVEF),effective orifice area (EOA),mean aortic pressure gradient (MPG),as well as artificial valve function of patients were measured at different time points (before operation,discharge,1 month and 3-6 months after operation) by echocardiography.The data were analyzed using one-way ANOVA analysis with SPSS software,and multiple comparisons were done using LSD student t test.Results The data from preoperative echocardiography indicated severe aortic stenosis in the 15 patients,with the average level of EOA as (0.55± 0.28) cm2 and MPG as (58.93± 14.96) mmHg (1 mmHg=0.133 kPa).Moderate paravalvular aortic regurgitation was observed in one patients,who was then received a second implantation.There was no significant difference between LVEDD,LAD,and LVEF when the patients were at discharge,1 month and 3-6 months after operation.The prosthetic valves were stable and conformed by echocardiography,while paravalvular leak regurgitation (1-2 mm) was observed in 7 patients.One patient died of other reasons.Compared with preoperative data,the EOA increased while MPG decreased when the patients were at discharge,1 month and 3-6 month after operation (t=6.619,7.357,6.401,all P ＜ 0.001;t=9.523,9.687,5.932,all P ＜ 0.001).Conclusion With careful patient screening and selection,TAAVI can be an effective treatment for high-risk severe aortic stenosis patients,in which echocardiography plays an important role during the surgery and follow up.

Adult ; Bone Neoplasms ; Ear Canal ; Ear Neoplasms ; Female ; Humans ; Osteochondroma