BACKGROUND:Current clinical studies seldom concern biomechanical properties of lateral plate combined with medial percutaneous lag screw. Moreover, effects of clinical application to distal tibial fractures are not investigated. OBJECTIVE:To explore biomechanical properties of lateral plate combined with medial percutaneous lag screw, and to analyze the repair effect on distal tibial fractures. METHODS:Six adult antiseptic tibia specimens were studied. Bone saw was used to make a bone defect in 1 cm length, which was fixed with lateral plate and lateral plate combined with medial percutaneous lag screw. Three point bending test, axial compression test and rotation test were performed. Clinical data of twenty cases of distal tibial fracture patients from the Department of Orthopedics of Hebei Medical University were analyzed and randomly divided into lateral plate groupand lateral plate combined with medial percutaneous lag screw group (n=10). Clinical repair effects were compared between the two groups. RESULTS AND CONCLUSION:(1) Biomechanical indexes of cadaver specimens: no significant difference in torsional strength was determined between the two groups (P> 0.05). Bending stress and axial displacement were significantly lower in the lateral plate combined with medial percutaneous lag screw group than in the lateral plate group (P< 0.05). (2) Repair surgery related indicators: operation time, intraoperative blood loss, length of stay and fracture healing time were significantly less in the lateral plate combined with medial percutaneous lag screw group than in the lateral plate group (P< 0.05). (3) Repair effects: There were nine cases of fracture healing in the lateral plate combined with medial percutaneous lag screw group 3 months after treatment. The total effective rate was significantly higher in the lateral plate combined with medial percutaneous lag screwgroup (90%) than in the lateral plate group (70%) (P<0.05). (4) These findings indicate that lateral plate combined with medial percutaneous lag screw has a unique advantage in resisting axial compression, torsion and bending. Its application to distal tibial fractures obtains ideal effects, can improve the clinical efficacy and stability.

The study was designed to observe the effects of fructose- 1 ,6 - diphosphate (FDP) on the stressed patients who were supported with total parenteral nutrition (TPN) after gastrectomy.Twelve cases of patients with gastric cancer were randomly divided into two groups.The control group was supported by TPN,and the FDP group received TPN plus FDP.The resulshowed thatin FDP group the serum levels of cortisol and glucogon declined and the urine 3- methyl- histidine excretin decreased with a better cumulative nutrogen balance when compared with control group.It sug- gested that FDP may lessen the protein catabolism and improve the results of nu- tritional support in stressed patients after trauma or surgical operation.

It is still difficult to achieve optimal nutritional effect in the septic patient.The objectives of this prospective study are to determine the effect of increasing N intake on the metabolic response to TPN in the septic patient,containing either0 .2 5 g N/ (kg? d) or0 .35 g N/(kg? d) .On the high- but not the low- N intake there were further beneficial effects on net protein levels in blood and nitrogen balance.The results showed that TPN containing high N instake can further achieve nitrogen bal- ance in the septic patient,although it may stimulate the catabolism of protein and further evoke the stress to responses.

Purpose:To evaluate the relationship between po stoperative survival rate and three stage systems (Nevin,AJCC,JSBS) of gallbladd er carcinoma. Methods:From October 1988 to December 1998 a total of 30 patien ts with gallbladder carcinoma underwent radical resection in the Xinhua Hospital . All patients were classified by 3 different methods of staging.The 1-year,3- year ,5-year postoperative survival rates were evaluated according to the stage . Results:All patients with stage Ⅰ were alive. There were less cases in Nevin’s stageⅡ,Ⅲ. The 3-year,5-year survival rates in patients wit h Nevin’s stage Ⅱ,Ⅲ were better than the other two classifications. The 5-ye ar survival rates in patients with Nevin’s stage Ⅲ were better than those with Nevin’s stage Ⅳ. The 3-year,5-year survival rates in patients with Nevin’s stage Ⅳ/Ⅴ were significantly better than the other two classifications (P

Colorectal cancer is induced by multiple factors.Multiple genes should be considered for the research of colorectal cancer.Single nucleotide polymorphisms,a new tumor gene researching method,play a key role in colorectal cancer researching.Finding colorectal cancer special SNP is vital for selecting high risk population and predicting the risk of developing colorectal cancer.

Gallbladder cancer is the most common malignancy of biliary tract with a very poor prognosis. The therapeutic strategy of gallbladder cancer has been improved in some aspects. Identifying the accurate stage is the basis of surgical treatment. Radical resection is the only choice of treatment which provides patients long survival. For most patients in T1a stage, simple cholecystectomy is adequate, but dissection of hepatoduodenal ligament should be added when the lesions located in neck and duct of gallbladder. Patients in T1b stage often need radical cholecystectomy. Radical cholecystectomy with Ⅳb and Ⅴ segmentectomy and lymphadenectomy of N2 nodes should be performed to patients in T2 stage. Extended right lobe resection can improve the prognosis of selected T3 and T4 patients.The effect of chemotherapy for gallbladder cancer remains unsatisfactory, and current chemotherapeutic regimens were based on 5-FU, gemcitabine or S-1. The effect of a new chemotherapeutic sensitization scheme with continuous infusion of somatostatin,epirubicin 5-FU/CF and cisplatin is under research, and the preliminary results are promising. Radiation shows some benefits to patients with gallbladder cancer, but its effects are still uncertain.

Objective To solve the problems that data can not be shared in HIS and PACS/RIS integration system,and optimize business processes to meet the growing needs for informationization hospital.Methods Through the use of standard protocol HL7 technology of electronic data transmission with different systems in health care field to develop HL7 Interface Engine,HIS system and PACS/RIS system are integrated tightly to achieve fully data sharing.Results After the completion of HL7 interface engine development,the data sharing problem of HIS and PACS/RIS are solved and improve work efficiency.Conclusion The ripe HL7technology is in line with international standards and the scalability is very good,not only improve the quality of treatment but also guarantee effectively the consistency of inside data in hospital.

Recently,the Society of Critical Care Medicine and the European Society of Intensive Care Medicine sponsored a 19-member Task Force to update the definitions of sepsis and septic shock at the forty-fifth Critical Care Medicine Annual Meeting in February 2016.Owing to an increased understanding of the harmful systemic response to infection,members of the multidisciplinary task force proposed that sepsis now be defined as life threatening organ dysfunction caused by a dysregulated host response to infection.To standardize the assessment of organ dysfunction,the Task Force members propose that provider use the sequential organ failure assessment(SOFA) score and quick SOFA (qSOFA).Although the systemic inflammatory response syndrome(SIRS) standard has high sensitivity and low specificity,the mortality of sepsis in the world has decreased significantly in the past 20 years.With the gradual realization of sepsis 3.0,will SIRS really be completely out of the stage of history? The SOFA and qSOFA criteria is not suitable for children.The author thinks that SIRS standard still has its practical application value.We need further studies on how to improve the sensitivity and specificity of sepsis diagnosis at the same.We should continue to validate sepsis 3.0.

There are much more multidrug-resistant organisms (MDRO) in the intensive care unit than ever.If the doctors could distinguish the colonization from infection of MDRO,they can make right decision on the rational clinical use of antibiotics to reduce resistant organisms and nosocomial infection.However,it's a confused problem for clinicians to distinguish between colonization and infection.Bacterial culture combined with clinical symptoms and signs maybe helpful,but it is limited.There should be more objective indicators.This article was aimed to state the definition and relationship between colonization and infection,and how to determine the colonization and infection of MDRO.

Objective To evaluate the safety and efficacy of laparoscopy-assisted gastrectomy (LAG) for advanced gastric cancer.Methods The clinical data were retrospectively analyzed in 108 patients undergoing radical LAG for advanced gastric cancer from March 2008 to November 2011.Results 98 out of 108 patients were followed-up,the follow-up rate was 90.7％,with medium follow-up period of 30 months (range 6-70 months).26 patients died and 3 patients developed recurrence during the follow-up period.The overall recurrence rate was 26.9％ (29/108),in which the recurrence rate was 0 for Ⅰ B cases,18.8％ (6/32) for ⅡA,30％ (6/20) for ⅡB,30.8％ (8/26) for ⅢA,and37.5％ (9/24) for ⅢB,respectively.The overall 1,2,3-year survival rates were 95.4％,88.9％,73.8％,and 1,2,3-year progression free survival rates were 93.5％,83.3％,73.8％,respectively.Conclusions Compared with open gastrectomy LAG is a safe and feasible surgical procedure with satisfactory 3-year survival in patients of advanced gastric carcinoma.