Objective] To sum up Pro. Fu Huazhou’s clinical experience in treating alopecia areata. [Method] By following the teacher clinic and sorting out the related medical materials. Summarize the mentor's academic view and clinical experience in the differentiation and treatment of alopecia areata, for proven cases.[Result] In professor Fu Huazhou's opinion, alopecia areata disease in Shaoyin and Jueyin, more close relationship with liver and kidney, virtual in the clinical setting is more, which is given priority to liver and kidney deficiency, embodies the JingXie homology, qi complement each other in the body, qi deficiency, blood deficiency, blood deficiency is also empty gas, the lung and fur, deficiency of lung function of dispersing pertains to drop, more hair loss. Alopecia areata can be roughly divided into blood deficiency and excessive wind, qi and blood stasis, qi and blood deficiency, liver and kidney deficiency syndrome and treatment according to patients' clinical performance, treats dialectically, and leaching liquid combination traditional Chinese medicine for external use at the same time, helps new hair regeneration, curative effect is remarkable. [Conclusion] Fu Huazhou ’s treatment of alopecia areata from liver and kidney, internal and external use, shows originality, curative effect, worth learning and promotion.

Chloroporphyrin derivative (CPD1) 20mg ? L-1 plus light 5min caused marked photohemolyses, At the dose of 10mg ? L-1 20mg ? L-1 plus light10min. the activities of AchEs in red cell membane and ATPase in liver mitochondria and G-6-Plus in liver microsome were markedly inhibited lipid peroxida- tion of red cell membrane was greatly enhanced by CPD1 plus light when CPD1 was irrad - iated the production of free radical of superoxide anion was initiated the amount of O2 production was depen-dent on CPD1 doses and irradiation time.

It is common in bacterial genomes of the integration of prophages. As an important participant of the vital movement of their hosts, prophages affect closely the biological properties of the hosts. Therefore, if we want to comprehend a bacterial genome fully, it is essential to recognize and understand accurately prophages in it. This article is a compendious review about the classification, distribution, identification, evolution of prophages and the interaction with their hosts.

Brachytherapy ; Cicatrix ; radiotherapy ; Humans ; Male ; Middle Aged ; Tracheal Stenosis ; radiotherapy

Objective To discuss morphology and biomechanics of the sacrum fractures so as to provide scientific basis for corresponding clinical treatment. Methods A total of 10 fresh pelvis specimens were collected for dynamic impact test and static destruction test, in the former one of which, the dynamic parameters were measured to make sure the dynamic characters of the fractures. Meanwhile, the fractures of the sacrum wing, the sacral foramina and the sacrum edge were made decalcification, slice of paraffin wax and staining (Masson, Mallory, HE) in order to make a cytological observation of the tissue. Results (1) The form of sacrum fracture or acetabulum fracture, crista iliaceis fracture was relevant to the impact energy. Low impact energy usually caused fractures of the ilium, acetabulum or sacroiliac crest. High impact energy resulted in following three kinds of fractures, just as the classification of Denis: sacral ala fractures belonged to typeⅠfractures, sacral hiatus fractures to type Ⅱ fractures and central vertebral canal fractures to type Ⅲ fractures. All three types of fractures might involve lateral or bilateral nerve roots. (2) There was a significant mechanic difference in regard of the mechanism of both dynamic destruction and static destruction of pelvis, ie, not only the limit pressure differed but also the former increased rapidly with the higher rate of the strain. The clash energy beyond 25 J would beget the cleft fractures of the sacrum via sacrum hiatus and even involve the nerve roots. The clash energy under 20 J usually resulted in fractures of the ilium and the sacrum. The clash energy between 20 J and 25 J more easily caused type Ⅰ fractures. While fracture of the ilium and the acetabulum would happen most in static destruction. (3) The cross section of the sacrum was cracked and the bone board of Haversian system is brittle, as led to separation of bone board and malposition of a few cross bone boards. Conclusions Under dynamic state, the sacrum fractures mostly belong to type Ⅰ and type Ⅱ (Denis classification of sacral fractures), usually involving the nerve roots. The sacrum fracture is relevant to the microstructure, the distribution of the bone trabecula, the osseous lacuna and the Haversian system of the sacrum. The fractures of the ilium and the acetabulum more frquently appear in static state, with slight wound of peripheral tissues.

Objective To investigate the application of a new type internal anastomotic appliance of pouch pliers in the retention of anus operation of mesal,low rectal carcinoma.Methods The data of 65 patients with mesal,low rectal carcinoma with the technique of the anal retention using KYGW type anastomotic appliance of pouch pliers were reviewed and analyzed retrospectively.Results 65 patients were coincided success only one time. Anastomotic fistula occurred after operation in 1 case,being cured and discharged at last,no anastomotic stricture. Conclusion The internal anastomotic appliance of pouch pliers in the anal retention of mesal-low rectal carcinoma is an efficient method with better cost-effectiveness and fewer complications,which is easy to manipulate and popular- ize.

Objective To study the effect of a distal protection device (Pereusurge GuardWire: GW) on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention. Method Acute STEMI patients treated with primary PCI were eligible to be studied. Inclusion criteria were: (1) within 12 hours from the onset of chest pain;(2) culprit leision with diameter stenosis≥70% and TIMI flow grade≤2. Exclusion criteria were:(1) patients undergoing thrombolytic therapy before PCI; (2) a culprit lesion in the left main coronary artery;(3)reference vessel diameter

Objective To explore the preventive and therapeutic effect of recombinant human interleukin-11(rhIL-11) on thrombocytopenia in children with non-lymphocytic leukemia after chemotherapy.Methods Sixteen children who had non-lymphocytic leukemia were divided into 2 groups by randomization,including a therapeutic group and a control group.RhIL-11[50 ?g/(kg?d)] was injected subcutaneously 24 h after chemiotherapy in the therapeutic group,and applied consecutively 10-14 days,and the control group was treated without RhIL-11.Duration of the thrombocytopenia,infusion of blood platelet,diversity of blood platelets counts and adverse effect were observed of the 2 groups.Differences between groups were examined using statistics analysis.Results There were 16 case-times(59.3%) in the therapeutic group that of could be cured without platelet transfusion,but that of control group only had 3 case-times(14.3%);the diffe-rence between 2 groups was significant(P

Objective: To evaluate the inhibitory effect of intraperitoneal sustained-release chemotherapy with 5-FU on the growth of H22 ascitic tumor in mice. Methods: Mouse H22 ascitic tumor model was established by intraperitoneal injection of 0.2 ml H22 ascitic cells (4 × 106 cells) and the animals were subsequently divided into 4 groups randomly, namely, the saline control group (received saline), peritoneal chemotherapy group (received common 5-FU), sustained-release chemotherapy group (received sustained-release 5-FU), and negative control group (received control sustained-release agent). The survival times of the mice were recorded in all groups. The apoptosis rates of H22 ascitic cells were analyzed with flow cytometry 9 and 12 days after injection of H22 cells and the proliferation index was calculated. Electron microscope was used to observe H22 cells 12 days after peritoneal injection. Results: The average survival time of peritoneal chemotherapy group ([13.7±1.7] d) was significantly shorter than that of sustained-release chemotherapy group ([15.3±2.0]d) (P<0.05), but was longer than those of saline control group and negative control group (P<0.05), with no significant difference between the latter 2 groups. The apoptosis rate of H22 cells in sustained-release chemotherapy group was lower than that in peritoneal chemotherapy group (8.1±0.9 vs 16.5±1.7, P<0.05) 9 days after injection of H22 cells, but was higher than the latter 12 days after injection (10.1±1.3 vs 7.6±0.8, P<0.05); besides, they were both higher than those of saline control and negative control groups (P<0.05), with no significant difference found between the latter 2. Electron microscopic results showed that some H22 cells in peritoneal chemotherapy group and sustained-release chemotherapy group had a typical apoptosis appearance, and most cells in control group remained unchanged. Conclusion. Intraperitoneal sustained-release chemotherapy using 5-FU can prolong the survival time of mice bearing tumors and can inhibit the growth of H22 ascitic tumors for a longer period of time.