1.Study on the characteristics of the image of primary liver cell cancer using triphasic helical CT
Journal of Medical Research 2004;27(1):56-62
51 patients with primary liver cell cancer determined by pathological anatomy or with liver tumors determined by ultrasound or CT image and AFP > 500ng/ml were investigated. Triphasic helical CT had detected diffused infiltration on 5 patients, multitumor on 20 and single tumor on 26 patients. On 46 patients with localized damage, there were 121 tumors sized 0.9-12.0 cm. Necrosis was common in > 5 cm tumors with a rate of 53.1%, but 21.5% if its size was not considered. Triphasic helical CT technique had reflexed the hemodynamic nature of the liver parenchyma and the primary liver cancer, therefore it gave prospective information helping the diagnosis and the decision of the treatment strategy.
Liver Neoplasms
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Neoplasms
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liver
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diagnosis
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Tomography, X-Ray Computed
2.Validation of a Chinese version of psychosocial impact of dental aesthetics questionnaire
Chinese Journal of Medical Aesthetics and Cosmetology 2011;17(2):128-131
Objective To translate the original English version of psychosocial impact of dental aesthetics questionnaire (PIDAQ) into Chinese version and to test the psychometric properties of the Chinese version for use among the Chinese young adults. Methods In accordance with standard procedures of international quality of life assessment project, the original English version of PIDAQ was translated into Chinese, pre-tested and cross-cultural adapted. Subsequently the Chinese version and two other scales, aesthetic component of the index of orthodontic treatment need (IOTN-AC) and perception of occlusion scale (POS), were administered to young adults, 140 of which were orthodontic patients on the first visit, and 296 were general residents without orthodontic treatment in Guangzhou.Reliability and validity of the translated scale were assessed. Results Cronbachs α of the translated scale was 0. 942, standardized Cronbachs α was 0. 943, corrected item-total correlation ranged from 0. 392 to 0. 812. PIDAQ and its 3 dimensions were significantly associated with IOTN-AC and POS.Conclusion The translated Chinese version of PIDAQ demonstrates good reliability and validity. Its good psychometric properties provide the theoretical evidence for further use in Chinese young adults.
3.Study of the trust on GP-based community health centers' services
Quan XUE ; Shaobo ZHANG ; Yong BAO
Chinese Journal of Hospital Administration 2013;(1):57-61
Objective To probe into the trust of residents on the health centers' service offered in their community in general for providing better family doctor services.Methods A custom-made trust scale for medical service (including 23 indicators) and random sampling were called into play.An imercept survey was made to 224 residents of different gender,age and education in a community in Beijing regarding their overall trust on medical service.Results The different satisfaction over their selection of the 23 indicators among residents of different gender is not significant statistically (P>0.05); the seven differences of the residents of different ages regarding their trust of the general medical service are significant statistically; the 11 differences of the residents of different education regarding their trust on the community health centers in general are significant statistically.Conclusion The GP-based community health centers are expected to improve the trust of residents on them in general,by means of enhancing government responsibility,government investment and the improvement of services of general practitioners.
4.Early diagnostic value of plasma and urine concentration of Intestinal fatty acid binding protein in gastrointestinal dysfunction or failure in the critically ill children.
Fan WANG ; Bao-quan ZHU ; Ding XU
Chinese Journal of Pediatrics 2007;45(9):712-713
Adolescent
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Child
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Child, Preschool
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Critical Care
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Fatty Acid-Binding Proteins
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blood
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metabolism
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urine
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Female
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Gastrointestinal Diseases
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blood
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urine
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Humans
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Male
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Metabolic Diseases
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blood
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urine
5.Successful treatment of paraquat poisoning with hemolytic anemia: a report of 1 case.
Bao-quan SUN ; Bo ZHAO ; Ping LI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2013;31(8):624-624
Anemia, Hemolytic
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chemically induced
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therapy
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Female
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Humans
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Paraquat
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poisoning
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Poisoning
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therapy
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Young Adult
6. Effect of retrograde perfusion with autologous blood through inferior vena cava on MDA and SOD in serum, liver and kidney during moderate hypothermic lower body circulatory arrest in pigs
Academic Journal of Second Military Medical University 2011;32(4):413-416
Objective To study the effect of retrograde perfusion through the inferior vena cava (IVC) during moderate hypothermic lower body circulatory arrest on malondialdehyde (MDA) content and superoxide dismutase (SOD) activity in the serum, liver and kidney of pigs. Methods Twenty healthy pigs were randomly divided into two groups: group A had moderate hypothermic lower body circulatory arrest for 90 min, group B had moderate hypothermic lower body circulatory arrest and retrograde perfusion through IVC at the same time. SOD activities and MDA contents in the serum, liver and kidney were analyzed before retrograde perfuston(T1), 1 h after circulatory arrest(T2), and 1 h (T3), 3h (T4), and 5 h (T5) after reperfusion. Results There were no significant differences in SOD activities and MDA contents in the serum, liver or kidney between the two groups at T1 (P<0.05). Serum MDA contents were increased and the SOD activities were decreased in both groups at T3, T4, and T5, with the changes in group B being significantly small than those in group A (P<0.05). MDA contents in the liver and kidney in group A were significantly higher and the SOD accivicies were significantly lower than those in group B at T2-T5 (P<0.05). Conclusion Retrograde perfusion with autologous blood through IVC can partly alleviate the ischemic-reperfusion injury of liver and kidney during moderate hypothermic lower body circulatory arrest in pigs, showing a protective effect on the hepatic and renal function.
7. Separation and purification of superoxide dismutase from blood by polyacrylic acid sodium and the influential factors
Chinese Pharmaceutical Journal 2013;48(23):1985-1990
OBJECTIVE: To purify superoxide dismutase from fresh pig blood by using definite molecular weight polyacylic acid sodium (PAAS) as dispersant, explore the effect of different molecular weight of polyacylic acid sodium on SOD activity, and compare the new process with the traditional process to determine the optimum molecular weight of polyacylic acid sodium for purification of SOD from blood. METHODS: Low, medium, and high molecular weight polyacylic acid sodium were used as highly efficient electrolyte with copper chloride as enzyme activator agent to improve the traditional blood purification technology via the key steps such as hemolysis, thermal alteration, cold acetone precipitation, ultrafiltration concentration, filtration chromatography and ion exchange chromatography. RESULTS: High purity enzyme was obtained, the enzyme activity was up to 5585 and 6 148 U · mg-1, and the product yields were 15.2% and 11.5%, respectively. The activity recoveries were 55.2% and 45.8% resectively after purification. SDS-PAGE showed a single stripe, and the subunit's molecular was around 16 × 103. Different molecular weight of PAAS played inconsistent role in the process of purification of SOD. PAAS with a solid content of 3.45% and a hemolysis volume of 20% was suitable for the purification of blood SOD. CONCLUSION: Low molecular weight PAAS is suitable as a polymer electrolyte to purify blood SOD, while the medium and high molecular weight PAAS are not appropriate for industrialized purification.
9.Diagnoses Evaluation of 64-slice Spiral CT Angiography in Cerebral Vascular Lesions
Mingzhu LI ; Min XU ; Kemin XI ; Quan BAO
Chinese Medical Equipment Journal 1989;0(04):-
Objective To explore the diagnosis evaluation of 64-slice spiral CT angiography(CTA) in cerebral vascular disease.Methods 64-slice spiral CT angiography of 48 patients with suspected clinically cerebral vascular diseases were analyzed retrospectively.The source images were got by TOSHIBA Aquilion VCT Scanner,and all axial images were transferred to an external workstation.The reconstructed images were processed into volume rendering(VR),multiplanner reconstruction(MPR) and maximum intensity projection(MIP),the values were valuably compared with the results of surgery or DSA.Results 30 cases were aneurysms,4 cases were AVM,8 cases were cerebral artery stenosis or occlusion,6 cases were normal.Conclusion The 64-slice spiral CTA is a valuable diagnostic method for various cerebral vascular diseases.
10.Effect of Serum Containing Rhizoma Chuanxiong on Proliferation and Differentiation of Mouse Embryonic Stem Cells
Deju JIANG ; Yi LUO ; Qian BAO ; Quan XIA
Journal of Guangzhou University of Traditional Chinese Medicine 2017;34(3):401-404
Objective To observe the influence of serum containing Rhizoma Chuanxiong on the proliferation and differentiation of mouse embryos stem cells(ESCs).Methods Mouse ESCs were co-cultured with serum containing Rhizoma Chuanxiong.The proliferation of ESCs was detected by CCK-8 method.The expression level of specific gene beta-myosin heavy chain (β-MHC) in cardiac myoblasts was detected by reverse transcription-polymerase chain reaction (RT-PCR).Results Compared with the blank rat serum group and the blank fetal bovine serum group,the differences of activities of ESCs in serum containing Rhizoma Chuanxiong group were in significant(P >0.05) and the expression level of specific gene β-MHC in cardiac myoblasts was increased (P < 0.05).Conclusion Serum containing Rhizoma Chuanxiong can promote the differentiation of ESCs into cardiac myoblasts.