ObjectiveTo discuss the influence of nursing intervention on psychological state of transfusion patients in outpatient and emergency department. MethodsSCL-90 questionnaires were used to investigate 600 transfusion patients in outpatient and emergency department to understand their psychological state. Psychological nursing was given to them before, during and after transfusion, SCL- 90 questionnaire was used again for investigation at the last day of transfusion,χ2 test was used to evaluate the results. ResultsAfter psychological care, the somatization, interpersonal relationships, anxiety, depres-sion, hostility and terrorism and other items significantly alleviated compared with those before interven-fion. ConclusionsTo grasp the patients' psychological state and give psychological care to them can ef-fectively reduce the adverse psychological reaction of patients, improve the quality of care and safety and promote the treatment and rehabilitation of diseases.