1.Staphylococcus Resistance in Nosocomial Infection: An Analysis
Chinese Journal of Nosocomiology 2006;0(03):-
OBJECTIVE To study the staphylococcus infection and the drug resistance among the outpetients and the inpatients, and to provide information for the clinical treatment.METHODS To cultivate and isolate bacteria according to the Clinical Laboratory Operation Regulation.Bacteria were identified with the automated analyzer VITEK-60.made by Bio-Merieux Company in France.The drug susceptibility was one with the method of single split agar diffusion.RESULTS Totally 159 strains of Staphylococcus were isolated from the outpatients,(46.1%) of which were MRSA.Most of the infection were caused through genital tract;390 strains of(Staphylococcus) were(isolated) from the inpatients,87.1% of which were MRSA.Most of the infection were caused through respiratory tract.Most of MSSA resisted to penicillin,but MRSA were sensitive to vancomycin and(teicoplanin.) (CONCLUSIONS) Preventing the spread of the MRSA is very important to the control of the nosocomial(infection).As far as the infective situation,most of the outpatients are infected through genital tract;while most of the inpatients are infected through respiratory tract.As far as the drug susceptibility,vancomycin is the best antibiotics,the next is teicoplanin.It is necessary to use combined drugs for the MRSA infection.
2.Effect of Heat-Clearing and Dampness-Eliminating Therapyon Soluble Interleukin-2 Receptor in Chronic Hepatitis Bwith Damp-Heat Syndrome
Shijun ZHANG ; Zexiong CHEN ; Shaoxian LAO ; Weijun ZHANG ; Qiugang CHEN
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(03):-
[Objective] To observe the therapeutic effect of heat-clearing and dampness-eliminating therapy for chronic hepatitis B with damp-heat syndrome and its influence on soluble interleukin-2 receptor (SIL-2R). [Methods] Chronic hepatitis B patients with damp-heat syndrome were divided into two groups by incomplete randomization. Group A ( n = 31) was treated with heat-clearing and dampness-eliminating therapy and Group B (n = 17) with routine western medicine for protecting hepatic function. SIL-2R level in peripheral blood was observed before and after treatment. [Results] Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TB) and SIL-2R in chronic hepatitis B patients were much higher than those in healthy volunteers before theatment and were decreased after treatment (P 0.05) and that of markedly effective rate was significant (P
3.Effect of serum from acute myocardial infarction rat on inducing rat bone marrow mesenchymal stem cells into cardiomyocytes
Yunxian CHEN ; Min HE ; Jianhua LIU ; Jiayu CHEN ; Huizhen CHEN ; Xiangzhong ZHANG ; Xiaoyu ZHU ; Qiugang CHEN ; Peng XIANG ; Xueyun ZHONG
Chinese Journal of Pathophysiology 1989;0(05):-
AIM: To induce rat bone marrow mesenchymal stem cells (BMSC) into cardiomyocytes and investigate the influence of serum coming from acute myocardial infarction (AMI) rat on the procedure. METHODS: The passage 3 BMSC were divided into six groups: groupⅠwas control group; groupⅡwas induced with 5-azacytidine; group Ⅲ was induced with 5-azacytidine and serum from AMI rat; group Ⅳ was induced with 5-azacytidine and serum from normal rat; group V and group Ⅵ were induced with serum from AMI rat or normal rat. The cardiac troponin T, GATA-4 and desmin were detected 30 days after induction. RESULTS: After inducing by 5-azacytidine, 5-azacytidine and two kinds of serum, some cells in the three groups differentiated into cardiac like cells. The expressions of cardiac troponin T, GATA-4 and desmin were positive in cells differentiated from BMSC. The troponin T expression in control group and group inducing by AMI serum alone were negative but GATA-4 and desmin expressed weakly. Some cells induced with 5-azacytidine and serum were slowly beating 2 weeks after induction, but the cells induced with 5-azacytidine alone was not beating.CONCLUSION: Serum from AMI can not induce BMSC to differentiate into cardiomyocytes, but it promotes BMSC differentiate into cardiomyocytes induced by 5-azacytidine and facilitate the differentiated cells to mature.
4.Effects of multi-component exercise intervention based on different rates of resistance training on physical function and depression status in elderly patients with frailty
Xiurong XU ; Qiugang ZHENG ; Jun CHEN
Journal of Clinical Medicine in Practice 2024;28(12):132-137
Objective To explore the effects of multi-component exercise intervention (MET) based on different rates of resistance training on physical function and depression status in elderly patients with frailty. Methods Eighty hospitalized elderly patients with frailty in the Geriatric Department were randomly divided into control group (