1.Standardization Realization and Application of CBM Retrieval Strategies for Commonly Used Words in Medical Sci-Tech Novelty Assessment
Journal of Medical Informatics 2009;30(7):51-53,56
The paper expounds the function and significance of establishing CBM retrieval strategies for commonly used words, it could not only promote the quality and efficiency but also have important significance to upgrade and standardize the quality of novelty as-sessment report.
3.Study on Artemisinin Transdermal Delivery Systems
Naijie WANG ; Lin QIU ; Feng DU
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(08):-
Azone. PG combined with azone showed a higher synergic effect of enhancing effectiveness. Conclusion National Starch polyacrylate pressure-sensitive adhesive was the most effective pressure-sensitive adhesive matrix, PVP-K30 was the most effective crystallization inhibitor, PG combined with azone were the most effective penetration enhancers.
4.Effect of Permeation Enhancers on the Percutaneous Absorption of Artesunate in Vitro
Lin QIU ; Naijie WANG ; Feng DU
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(10):-
IPA.Skin permeation was significantly enhanced by increasing the loading concentration of OA or NMP,larger IPA amount(8%) or PG amount(20%) could inhibit the permeation of artesunate.Conclusion Oleic acid was found to be the most efficient enhancer for artesunate,10% is the most effective concentration.
5.An Improved Method for Determination of Cyanide in Drinking Water
Qingru QIU ; Yaping ZHANG ; Zixian DU ;
Journal of Environment and Health 1992;0(02):-
Objective To resolve the problem that qualified chloramine T was difficult to purchase for some basic laboratories Methods Using the solution of available chlorine prepared by bleaching power instead of chloramine T, the method for determination of cyanide in drinking water was improved Results The data obtained by this assay accorded with Beers Law in the range of 0~2 0 ?g/25 ml cyanide The detection limit,relative standard deviation,and recovery rate were 0 04?g,2 69%~3 09% and 97 50%~99 17% respectively Conclusion This method for determination of cyanide in drinking water was simple and easy to operate and presented good precision and accuracy
6.Eye Movement Research on Comprehension Monitoring in Reading between Students with and without Hearing Impairment
Xiaoming LIU ; Xiaoxin DU ; Tianlong QIU
Chinese Journal of Rehabilitation Theory and Practice 2014;(6):548-553
Objective To compare the comprehension monitoring in reading between students with and without hearing impairment. Methods An error detection paradigm and an eye-movement recordings method were used in two samples of hearing impairment students and no-hearing impairment students with passages that contained inconsistencies with interval 2 sentences, 4 sentences, 6 sentences and 8 sentences. Results The scores of reading comprehension, the index of tradition monitoring and the index of eye movement were lower in the hearing impairment students than in the no-hearing impairment students (P<0.05). Conclusion The comprehension monitoring ability in reading is poor in the hearing impairment students.
7.Association of neck circumference and metabolic syndrome as well as its components in type 2 diabetes
Liping ZHANG ; Qing QIU ; Jian DU
Clinical Medicine of China 2015;31(6):509-513
Objective To investigate the relationship between neck circumference and metabolic syndrome(MS) and its components in type 2 diabetes Methods A total of 272 subjects with type 2 diabetes were recruited.According to the diagnostic criteria of MS,all subjects were divided into MS group and non-MS group.According to neck circumference tertile,all subjects were respectively divided into male and female of three groups to analyze the relationship between neck circumference and MS and its components.Male:Q1<38.8 cm,Q2=(38.8-41.3) cm,Q3≥41.4 cm;female:Q1<34.0 cm,Q2=34.0-36.3 cm,Q3≥36.4 cm.The optimal cut-off points of neck circumference were used to determine the MS by ROC curve.Results (1) Compared with non-MS group,subjects in MS group had significantly higher neck circumference((38.3±3.2)cm vs.(36.1±3.7) cm),waist circumference((94.1±8.4) cm vs.(82.7±10.8) cm),waist-hip ratio(0.93±0.06 vs.0.88± 0.08),body mass index ((26.2 ± 2.9) kg/m2 vs.(23.9 ± 3.5) kg/m2),fasting plasma glucose(9.0(6.7-11.5) mmol/L vs.7.7(5.9-10.2) mmol/L),systolic pressure(140(130-150) mmHg vs.130 (120-130) mmHg),diastolic pressure (80 (80-90) mmHg vs.80 (75-85) mmHg),triglycerides (1.9(1.4-2.8) mmol/L vs.1.2 (0.9-1.5) mmol/L),low-density lipoprotein cholesterol (LDL-C) ((3.3 ± 1.0)mmol/L vs.(3.0±0.9) mmol/L) and blood uric acid((322.7±90.1) mmol/L vs.(270.3±82.3) mmol/L),and the differences were significant(t or Z=-4.843,-8.622,-5.157,-5.592,-2.729,-5.723,-3.847,-6.856,-2.123,-4.545;P<0.05).While the level of total cholesterol((2.7±2.8) mmol/L vs.(4.9±1.3)mmol/L) and high-density lipoprotein cholesterol (HDL-C) (1.0 (0.8-1.2) mmol/L vs.1.2 (1.1-1.5)mmol/L) were decreased,and the differences were significant (t or Z =-2.269,-7.068;P < 0.05).(2)Compared with those with lowest tertiles(Q1 <38.8 cm) of neck circumference,male subjects with highest tertile (Q3≥41.4 cm) had higher level of waist circumference((97.8±8.6) cm vs.(89.9±8.5) cm),waist-hip rati (0.96±0.07 vs.0.93±0.06),body mass index((27.4±2.1) kg/m2 vs.(23.8±2.3) kg/m2),blood uric acid ((374.0±85.6) mmol/L vs.(305.8±73.6) mmol/L),and the differences were significant(P<0.05).While age((52.1±10.7) years vs.(60.4±11.8) years) andHDL-C((1.0±0.3) mmol/Lvs.(1.2±0.5) mmol/L) were decreased,and the differences were significant (P<0.05).Female subjects with higher tertile (Q3 ≥ 36.4 cm) had significantly higher level of waist circumference ((96.8 ± 10.1) cm vs.(79.5 ± 8.5) cm),waist-hip ratio(0.94±0.07 vs.0.86±0.06),body mass index((28.5±3.1) kg/m2 vs.(21.9±2.2) kg/m2),blood uric acid((295.2±94.3) mmol/L vs.(244.6±62.3) mmol/L),the frequency of MS(83.3%(40/48)vs.21.7%(10/46)) than with lower tertile(Q1<34.0 cm).(3) Logistic regression analysis showed that neck circumference (β =0.187,P < 0.001) was an independent risk factor of MS (y =0.187x-6.613).(4) The optimal cut-off points of neck circumference to MS were 40.1 cm (AUC =0.682,P=>0.008) in male,and 35.3cm (AUC =0.766,P< 0.001) in female.Conclusion Neck circumference increases when type 2 diabetes patients with MS.Neck circumference is an independent risk factor for MS,which can be used as an indicator to evaluate MS.
8.Population intervention strategies towards delaying the onset of dementia
Chengxuan QIU ; Zhongrui YAN ; Yifeng DU
Chinese Journal of Behavioral Medicine and Brain Science 2017;26(6):501-506
As the number and proportion of aging population increase,dementia has posed tremendous challenges to the sustainable social and economic development of many countries in the world.Thus,dementia has been identified as a global public health priority.Clinically,there is currently no cure for dementia.However,in the past decades epidemiological research has suggested that cardiovascular risk factors and psychosocial factors over the life-course could significantly affect the risk of dementia occurrence later in life.Of these factors,smoking,diabetes,and midlife hypertension,obesity,and high cholesterol might contribute to the clinical onset of late-life dementia by causing cerebral macro-and microvascular damage and neurodegeneration,whereas high educational attainments in early life and social engagement,physical and mentally-stimulating activities during adulthoods might help maintain late-life cognitive function by increasing cognitive reserve.Thus,theoretically clinical onset of dementia is likely to be postponed by implementing interventions targeting these factors over the lifespan.In recent years,evidence from research in Europe and North America has emerged that multimodal interventions that consist of intensive control of cardiovascular risk factors,balanced diets,physical activity,and cognitive training may help maintain cognitive function among individuals at risk for dementia.We call that population intervention research against dementia should be strengthened in China.Identifying the intervention programmes against dementia that are effective specifically among Chinese population is of high relevance for developing the national dementia action plan,and thus effectively dealing with the huge challenges by dementia.
9.Plasma BNP Level Change and Clinical Value in Acute Pulmonary Embolism
Linlin DU ; Qiaomeng QIU ; Zhongqiu LU
Journal of Medical Research 2006;0(03):-
Objective To evaluate plasma BNP level change in acute pulmonary embolism and its clinical value.Methods 33 cases were diagnosed by CT pulmonary angiography or DSA.they were divided into two groups:the group with right ventricular(RV)dysfunction group and the group without right ventricular(RV)dysfunction.Plasma BNP was detected by Triage BNP test.otherwise,we observed severe clinical presentation、 death rate and mechanical ventilation in two groups.Results Plasma BNP level is higher in the group with RV dysfunction(288?102pg/ml)than that in the group without RV dysfunction(61?32pg/ml)(P
10.The Changes and Significance of Electrocardiogram and Myocardial Damage Index in Patients with Acute Organophosphorus Pesticide
Lingwen LI ; Linlin DU ; Qiaomeng QIU
Journal of Medical Research 2006;0(06):-
Objective To investigate the change and significance of electrocardiogram and myocardial damage index in patients with acute organophosphorus pesticide (AOPP).Methods 71 hospitalized patients in EICU with AOPP from January 2000 to June 2006 were recorded.The patients were divided into 3 groups: mild poisoning group (n=18),moderate poisoning group(n=22) and severe poisoning group (n=31).Electrocardiogram(ECG), serum creatine kinase(CK), serum creatine kinase isoenzyrne MB(CK-MB),lactate dehydrogenase(LDH) and TnI were detected,the relation between the above-mentioned indexes and the toxical degree were analyzed.Results Abnormal ECG had a rasied tendency along with increase of the poisoning degree.The incidence of Ⅱ~Ⅲ atrioventricular block, atrial premature beats, ventricular premature contraction, ventricular tachycardia and ventricular fibrillation in severe poisoning group significantly increased compared with that in mild poisoning group and moderate poisoning group(P