2.The Relationship between the Effect of Conservative Treatment and the Results of CT Scan in Lumbar Disc Prolapse
Ping QIU ; Haili SU ; Rune CHANG
Chinese Journal of Sports Medicine 2001;20(1):48-49
In this paper,we reported the results of 36 cases with lumbar disc prolapse through conservative treatment in order to observe the relationship between the effect of conservative treatment and the results of CT scan.We found that the effectiveness of treatment was related to the size and location of the disc protrusion as well as the course of disease.The results suggested that these factors should be considered fully during selecting the methods of conservative treatment or operation in lumbar disc prolapse.
3.Effects of hyperbaric oxygen therapy on recovery of cognitive function in stroke patients on hemodialysis
Jing CHANG ; Xiuqin SONG ; Xiaojun QIU
Chinese Journal of General Practitioners 2012;11(6):459-461
To explore the clinical efficacies of hyperbaric oxygen therapy on the recovery of cognitive function in stroke patients on hemodialysis.Forty stroke patients on hemodialysis were assigned randomly into hyperbaric oxygen therapy (HBO) (n =20 ) and routine therapy groups (n =20).Patients of HBO group received both hyperbaric oxygen therapy and routine therapy.Nerves functions and cognitive function were observed before and after therapy to compare the clinical outcomes.Neuropsychological tests,minimental status examination (MMSE) and activities of daily living (ADL) were used for assessing cognitive function.Then the outcomes were compared with those of the control group.Nerves function and cognitive dysfunction of the treatment group had significant improvement (P < 0.01).Hyperbaric oxygen can significantly improve cognitive dysfunction in stroke patients on hemodialysis.
4.Influence of edaravone on MDA and expression of Hsp-70 and Bcl-2 in the perihematoma region in rats.
Lin YIN ; Xiaofeng QIU ; Sujie CHANG
Chinese Journal of Practical Internal Medicine 2002;0(08):-
Objective To study the influence of edaravone on malondialdehyda(MDA)and expression of Hsp-70 and Bcl-2 in the perihematoma region in rats.Methods A total of 120 health male rats were randomly divided into false-operation group(n=20)、intracerebral hemorrhage(ICH)-therapy group(n=50)and ICH control group.Each group was further divided into 5 subgroups respectively according to 6 h、24 h、48 h、72 h and 5d after model creation.Cerebral hemorrhage model was duplicated with the method created by Fredrik.Brain water content and MDA were measured.Expression of Hsp-70 and Bcl-2 were assayed in each group with immunohistochemical method.Results Brain water content and MDA were lower in ICH-therapy group than those in control group(P
5.MRI Diagnosis of Primary Intracranial Teratoma
Shijun QIU ; Xuelin ZHANG ; Renmin CHANG
Journal of Practical Radiology 2001;0(08):-
Objective To investigate the role of MRI in diagnosis of primary intracranial teratoma.Methods Nine cases of primary intracranial teratoma proved by operation and pathology were examined by MRI before operation.MRI features were analysed retrospectively.Results The localized and qualitative rates were 100% and 88.8% respectively.The characteristic MRI appearances of primary intracranial teratoma were as follows:(1)The tumor was lobular in shape with clear margin;(2)The tumor had heterogeneous signal intensity ;(3)Inhomogeneous Gd-DTPA enhancement in most of the tumors.Conclusion Multiplanar imaging and Gd-DTPA enhancement in MRI are helpful in diagnosis and differential diagnosis of teratoma.
6.Effect of early interventions with He-Ne laser and infrared radiation for preventing neuralgia Following herpes custer
Chinese Journal of Neuromedicine 2008;7(11):1177-1178
Objective To investigate the effect of early interventions with helium-neon (He-Ne) laser and infrared physical therapy in the treatment of herpes coster. Methods Sixty-six patients with herpes zoster and concurrent severe neuralgia were randomly divided into treatment and control groups (n=33). The patients in the control group received routine treatment, and early He-Ne laser and infrared treatment was administered in addition to the routine treatment in the treatment group. The visual analogue scale (VAS) was used to evaluate the therapeutic effects in the two groups. Results Early intervention with laser and infrared treatment produced significantly better therapeutic effects than the routine treatment (U=193.520,P=0.000). In the treatment group, the rate of excellent or good therapentic effects and the response rate was 90.9% and 100.0%, respectively, without occurrence of postherpetic neuralgia;in the control group, the rate of good therapeutic effects and the response rote was 63.6% and 81.8%, respectively, and postherpetic neuralgia occurred in 3 eases (9.1%) after the treatment. Conclusion Early intervention with He-Ne laser and infrared treatment in patients with herpes coster helps achieve rapid control of the condition, shortens the treatment course, and reduces the occurrence of postherpetic neuralgia.
7.Ghrelin participates in the two-way regulation of the motility of the small intestinal smooth muscle in rats
Chengguang YANG ; Ying ZHENG ; Wencai QIU ; Xin CHANG
Chinese Journal of General Surgery 2012;27(10):812-815
Objective To investigate the effect and mechanism of Ghrelin on the contraction and relaxation of rat small intestinal smooth muscle. Methods The effect of different concentrations of Ghrelin (0;20;40;80 μg/kg) on the small intestinal transit in vagotomized rats in vivo and Ghrelin (0.01; 0.1;0.5 ; 1.0 μmol/L) on the contraction and relaxation of rat small intestinal smooth muscle strips in vitro was observed,the locations of Ghrelin receptors (GHS-R1 a) in small intestinal muscle layers were detected by immunofluorescency. Results Ghrelin dose-dependently increases small intestinal transit (( 25.4 ± 1.0)%,(33.7 ± 1.9)%,(39.3 ±2.4)%,(44.7 ±2.1)%),enhances the contraction ((67.0 ±2.4)%,(149.5 ±3.3)%,(187.1 ±4.7)%,(213.5 ±3.4)%) and relaxation ((35.3 ± 1.1)%,(62.9 ± 3.8 ) %,( 79.6 ± 2.7 ) %,( 94.6 ± 2.2 ) % ) of smooth muscle strips mediated by carbachol.Ghrelin receptors were mainly located on membrane of the nerve cells in the muscle layers,while no receptors exist on membrane of smooth muscle cells. Conclusions Ghrelin enhances the effect of contraction and relaxation of rat small intestinal smooth muscle mediated by cholinergic neurotransmitters activating nerve cells in the enteric plexus.
8.Inhibitory effect of endothelin receptor antagonist on increased vascular endothelial growth factor level of retina in diabetic rats
ke-bo, CAI ; yao-hua, SHENG ; chang-bin, QIU
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(04):-
Objective To observe the inhibitory effect of endothelin receptor antagonist on increased vascular endothelial growth factor(VEGF) level of retina in diabetic rats. Methods Male Wistar rats were randomly divided into three groups: normal control group,diabetic group(diabetes without treatment) and treated group(diabetes treated with endothelin receptor antagonist).The rats were killed after 24 weeks.Levels of VEGF in retina of rats were detected by ELISA. Results Levels of VEGF were significantly lower in treated group than diabetic group(P
9.Mechanism of the anti-UC effect of Fructus Amomi based on network pharmacology
Chang-wei CHAI ; Hai-jing ZHANG ; Lian-qiu WU
Acta Pharmaceutica Sinica 2022;57(11):3345-3355
We predicted the anti-ulcerative colitis (UC) mechanism of Fructus Amomi based on network pharmacology. The anti-UC activity of Fructus Amomi were investigated by
10.Research of Sequential Extraction Procedure for Heavy Metals in Sediments from Mariculture Area
Pengran GUO ; Dehai MOU ; Chang WANG ; Rongliang QIU ; Hong DU
Chinese Journal of Analytical Chemistry 2009;37(11):1645-1650
A sequential extraction procedure has been proposed for the evaluation of the speciation of heavy metals including Cd,Cu,Pb and Zn in sediments from mariculture area,and the speciation of heavy metals was separated and defined as acid soluble fraction,reducible fraction,fraction bound organic matter,fraction bound sulfides and residual fraction. Matrix effects of high salinity on the determination of heavy metals in sediments were eliminated by matrix matching and internal standard methods when inductively couple plasma optical emission spectroscopy (ICP-OES) and mass spectroscopy (ICP-MS) were used,respectively. The results showed that the measured values of marine sediment reference materials were consistent with the standard values when the digestion solutions were determined after dilution. The extraction results of the prepositional extraction procedure and European Community Bureau of Reference Program (BCR) procedure were compared and the selectivity of extractants was investigated. The preliminary studies indicated that this sequential extraction procedure was applicable for evaluating the speciation of heavy metals in sediment with organic substances pollution and eutrophication,especially for fraction bound organic matter and fraction bound sulfides.