1.Computational Pharmacology of Xianhe Yanling Recipe in Anti-tumor Activity
Ming JIANG ; Qisheng ZHENG ; Guangyun YU ; Wei LONG ; Peixun LIU
Herald of Medicine 2014;(11):1401-1406
Objective To explore the antitumor mechanism of xianhe yanling recipe( XHYLR ). Methods The mechanism of action of 241 compounds contained in the Chinese medicine, XHYLR was studied by using computational pharmacological. Methods including molecular docking,biotechnology network,chemical space technology and the prediction of absorption,distribution,metabolism,excretion and toxicity( ADME/T). Results Most of the compounds in XHYLR had good drug-like properties. Distribution of 241 compounds in chemical space also revealed that these compounds showed similar anti-tumor activity. It suggested that the prescription of XHYLR was reasonable. The phenomena that one molecular interacted with multiple target proteins and several molecules interact with one target protein were observed in XHYLR. For example,the COX-2 interacted with 40 micromolecules,and catechin interacted with five targets including COX-2. Conclusion These results are helpful for understanding the complicated mechanism of anti-tumor activity of XHYLR.
2.Writing Specifications and Analysis of Frequently Asked Questions of Electronic Medical Record
Yunfu ZHANG ; Jiancheng XU ; Qi WANG ; Qisheng LONG
Chinese Medical Equipment Journal 1989;0(04):-
Objective To emphasize the correlation and concordance of electronic medical record through analysis of frequently asked problems on handwritten medical record.Methods The problems of electronic medical record were classified and found the typical cases to analyze.Results In order to improve the quality of medical record,the quality control of electronic medical record must be strengthened and the phenomenon that some doctors pay attention to hand-written med-ical record more than electronic medical record must be overcame.Conclusion The normative management of electronics medical is strengthened that is fundamental guarantee for paper-based medical records.
3.Research on Resident Prescription and Dispensing System
Mingde DENG ; Jiancheng XU ; Qisheng LONG ; Huazhen LU
Chinese Medical Equipment Journal 2003;0(10):-
Objective To study and establish the automatic resident prescription system and automatic dispensing system in Center Drug Store based on NO.1 Military Project. Methods According to the Prescription Administrative Policy (2007, Chinese Ministry of Health), automatic system was designed to link each drug store of different departments to the center drug store. Results It is proved that the design is appropriate according to the application of this system in many military hospitals. Conclusion The system not only gives a good administration of drug, but also decreases the work load and increase work efficiency of center drug store.