1.Experimental study of AA types model of the Yellow fluid disease
Qirigeer ; Purevsuren C ; Ariunaa ; Rashnamjil
Mongolian Pharmacy and Pharmacology 2019;15(2):46-48
Abstract
A yellow-fluid disease is a long-term disease that is common among Mongolians. A treatment of yellow fluid disease has an important place in Mongolian traditional medicine, and it is very complex condition due the continuous environmental and the climate change as well as overall evolving of other diseases. Rheumatoid arthritis (RA) is one of the most common disease with complex systemic nature and caused by autoimmune disorders.
This article is about inflammatory design of an affiliated member. The experiment was carried on rats, divided into two groups: healthy control groups and study groups. RA was developed in a study group rats and carefully observed. Rheumatism swelling level of rats were measured for 50 days. The result of the observation is the maximum swelling of study group were at third and thirty first days, and the swelling is slowly reduced until day 50, when the rheumatoid-inflammatory were healed. The aim of this study is to set the basis for future yellow-fluid disease study.
2. Chemical constituents of Lomatogonium carinthiacum and Halenia corniculata
Laxinamujila BAI ; Gang BAO ; Gang SUDABILIGE ; Gang CHAOGEBADALAFU ; Chenlin HE ; Chenlin QIRIGEER ; Laxinamujila BAI ; Shuzhen BAI
Chinese Herbal Medicines 2022;14(3):459-463
Objective: To study the chemical constituents from traditional Chinese (Mongolian) medicine, Lomatogonium carinthiacum and Halenia corniculate. Methods: The chemical constituents were isolated and purified by silicagel column, Sephadex LH-20, ODS and high performance liquid chromategramphy. The structures were identified by NMR and MS analysis technics. Results: Twelve compounds were isolated and identified as isovitexin (1), Luteolin-5-O-β-D-glucoside (2), Isosaponarin (3), Luteolin-7-O-β-D-glucoside (4,7), 1,4,8-Trimethoxy-xanthone-6-O-β-D-glucoronyl-(1 → 6)O-β-Dglucoside (5), friginosideD (6), 1-hydroxy-2,3,5-trimethoxyxanthone (8), 1-hydroxy-2,3,4,5-tetramethoxyxanthone (9), 1-hydroxy-2,3,4,7-tetramethoxyxanthone(10), 1-hydroxy-2,3,4,5,7-pentamethoxyxanthone (11) and usnic acid (12). Conclusion: Compounds 6 and 12 are obtained from L. carinthiacum and H. corniculate for the first time.
3.Study on Chemical Constituents of Mongolian Medicinal Material Gentiana Veitchiorum
Baogang ; Tunuomula ; Chaogebadalafu ; Sudabilige ; Chenlin HE ; Aodungerile ; Qirigeer ; Laxinamujila
Chinese Journal of Modern Applied Pharmacy 2024;41(1):27-32
OBJECTIVE
To research the chemical components of Mongolian medicinal material Gentiana veitchiorum.
METHODS
Separation and purification were conducted using silica gel column chromatography, Sephadex LH-20 gel column chromatography, and preparative HPLC, and the compound structure was identified through spectral data and physicochemical constants.
RESULTS
Ten compounds were obtained from the separation of Gentiana veitchiorum. The compounds were respectively authenticated as 2,3-dihydroxybenzyl alcohol β-glucopyranoside(1), gentiopicroside(2), 2'-(O, m-Dihydroxybenzoyl) sweroside(3), isoorientin(4), isoorientin-3'-methyl ether(5), isovitexin(6), isoorientin-4’-O-glucopyranoside(7), isosoapin(8), ursolic acid(9), β-Sitosterol(10).
CONCLUSION
The compound 1 is authenticated as the new benzyl alcohol glycoside. The compound 10 is firstly separated from this medicinal plant.