Objective To investigate the relationship between the levels of serum bilirubin,uric acid(UA) and coronary heart disease unstable angina pectoris.Methods The leves of total bilirubin (TBIL),direct bilirubin (DBIL),indirect bilirubin(IBIL) and UA in venous blood by limosis were determind in 202 patients with unstable angina pectoris.We determine the different levels of TBIL,DBIL,IBIL and UA when they were suffering from angina pectoris.Then we respectively determine the levels of TBIL,DBIL,IBIL and UA in 3 months,6 months and 12 months after they had been suffered from angina pectoris.Results The levels of serum bilirubin were lower and UA were higher,when the patients were suffering from angina pectoris.Conclusion We can indirectly assess the oxidative and antioxidative activities by testing bilirubin and UA in unstable angina pectoris.

Tho effects of native isosorbide mononitrate ( ISMN ) on the hemodynamics in rats with early myocardial infarction by left coronary artery occlusion were investigated. LVSP and dP/dtMAX were increased, and LVEDP was decreased with ISMN 5mg/kg i.v. 20 min after coronary occlusion. However, ISMN did not significantly effect the HR, SAP, DAP and MAP. The results showed that ISMN can improve cardial function in early myocardial infarction.

Objective To study the effect of early intensive insulin therapy on the prognosis of critical old patients.MetlIods 76 critical old patients(＞65 years)were randomly divided into intensive insulin therapy group and control group,which were given intensive and routine insulin respectively,and biological parameters of organ func-fion and main prognostic indexes were recorded.Results The safety of intensive insulin therapy Was better.After bloed sugar was controlled strictly by intensive therapy,the incidences of aucte renal,heart and liver failure reduced obviously.There were obvious differences in mortality and the incidence of nosoeomial infection.Conclusion For critical old patients,early intensive insulin therapy can control blood glucose more effectively and promptly and im-prove the clinical curative effect.

Objective To compare the prevent effect of biliary retrograde infection in the uncut and cut Roux-en-Y cholecystojejunostomy. Methods Sixteen Begle dogs were divided into two groups randomly. One group was performed with the uncut Roux-en-Y cholecystojejunostomy(the uncut group) and the other was performed with the cut Roux-en-Y cholecystojejunostomy (the cut group). The categories of bacterium in the the Roux limb before and twelve weeks after operation, and the biliary duct pressure of the anastomotic stoma were detected. The changes of the categories of bacterium before and after operation, the categories of bacterium and the biliary duct pressure after operation in two groups were analyzed. Results The isolating rate of G-aerobic bacteria and anaerobic bacteria was 37.50% and 6.25% before operation; in the uncut group, the isolating rate was 62.50%, 12.50%,with no significance difference comparing to preoperation(p＝0.390、1.000). In the uncut group the isolating rate was 87.50%, 75.00%after operation, with significance difference comparing to preoperation (p＝0.033、0.001).The isolating rate of anaerobic bacteria after operation in the cut group is higher than the uncut group,the difference is significance (p＝0.041). And the biliary duct pressure in the cut group is higher than the uncut group(p<0.001).Conclusion The uncut Roux-en-Y cholecystojejunostomy was more effective in prevent biliary retrograde infection.

This review comprehensively summarizes clinical assessment tools which have been developed and validated for cholinergic urticaria (CholU) , involving diagnosis and severity assessment of CholU, assessment of patients′ quality of life, and assessment of disease control. The application methods and status of relevant tools in clinical practice are introduced in detail.