Objective To observe the effect of Gongxuening for the women placing the IUDafter cesarean section, and to analyze the effect and value of Gongxuening on intrauterine device placement after cesarean section. Methods 156 women who received voluntary intrauterine device after cesarean sectionin theShengzhou Maternal and Child Health Hospital of Shaoxing, Zhejiang were as the observation object. According to whether the application of Gongxuening, they were divided into two groupsafter treatment, the Gongxuening group of 75 cases (using Gongxuening + Nifloxacin) and the control group of 81 cases (using norfloxacin). The changes of serum inflammatory indexes were compared between the two groups before and after operation, and the uterine bleeding was compared between the two groups. Results After operation, the levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-10 (IL-10) were with a significantfluctuation, and at the same time, Gongxuening group TNF-α, IL-6, IL-10, 24hours after surgery, postoperative 7d was significantly lower than the control group, the difference was statistically significant (P< 0.05). After treatment, the WBC of Gongxuening group 24hours after surgery, postoperative 7d was significantly lower than the control group, but the Hb 24 hours after surgey was significantly higher than the control group, the difference was statistically significant (P<0.05). The bleeding volume2h, 24h, bleeding stop time and puerperium duration in the Gongxuening group were significantlylower than the control group, the difference was statistically significant (P<0.05). Conclusion After cesarean section maternal IUD use Gongxuening capsule treatment, not only can effectively inhibit the expression of serum inflammatory markers, and can shorten the time of uterine bleeding, reduce bleeding, prevent postoperative anemia. It is suggested to pay more attention to clinical treatment.