Objective To evaluate the attitudes of clinical nurses toward caring for the dying patients, and possible influencing factors concerning the attitudes were investigated, so as to provide a scientific basis for further intervention, thus improving the positive attitudes toward care of the dying patients in the future research. Methods A convenience sampling method was used to recruit 770 nurses from 15 hospitals located in 5 provinces in China. A demographic survey, Chinese version of Frommelt Attitudes Toward Care of the Dying Scale Form B (FATCOD-B-C) and Chinese version Death Attitude Profile-Revised were employed in the survey. Results FATCOD-B-C scale was used to evaluate the attitudes of nurses toward caring for dying patients, with the mean score of all FATCOD-B-C item being 95.62 ± 7.45. To analyze relationship among demographic variables and the total score of FATCOD-B-C. Univariate analysis revealed that age group (F=2.285), years employed as a nurse (F=3.353), educational background (F=5.581), technical title (F=5.692), level of hospital (t=2.058), religious beliefs (t=-2.788), previous education on death and dying(F=9.743), previous experience in dealing with terminally ill persons (t=2.761) had significant influence on the nurses' attitudes toward caring for dying patients and families(P<0.05). Multiple linear regression analysis indicated that nurses' attitudes toward caring for dying patients had been affected by those factors, among which the most influential factor was educational background. Conclusions It shows that nurses'FATCOD-B-C scores are at a low level. It is suggested to improve nurses' positive attitudes of caring for dying patients and their families by making the specific methods based on the influencing factors, thus improving the development of palliative care.

Objective:To explore the willingness to engage in geriatric nursing services of students in geriatric related majors in universities of Xinjiang Uygur Autonomous Region, China (Xinjiang for short) , and analyze its influencing factors, so as to provide a reference for cultivating the geriatric nursing service personnel in Xinjiang.Methods:From September 2019 to July 2020, 976 students in geriatric related majors (the nursing major and geriatric service and management major) from 2 universities, a medical university and a vocational university in Xinjiang, were selected as the research object. Students were investigated with the Students' Willingness to Engage in Geriatric Nursing Services Questionnaire, and 50 students were interviewed with the structured interview.Results:Among 976 university students in geriatric related majors, 606 (62.09%) were willing to engage in geriatric nursing services. Logistic regression analysis showed that attitudes towards the aged, registered residence, experience of caring for the aged, living with the aged, attention to geriatric nursing information, and views on the prospects of geriatric nursing services were the influencing factors of students' willingness to engage in geriatric nursing services with a statistical difference ( P<0.05) . The results of grey relation analysis showed that the driving strength of the influencing factors of the willingness to engage in geriatric nursing services of students in geriatric related majors from strong to weak was views on the prospects of geriatric nursing services (the relation index was 0.944) and attitudes toward the aged (the relation index was 0.828) , experience of caring for the aged (the relation index was 0.763) , attention to geriatric nursing information (the relation index was 0.658) , living with the aged (the relation index was 0.600) and the registered residence (the relation index was 0.563) . Conclusions:The most critical influencing factor for students in geriatric related majors in Xinjiang universities to engage in geriatric nursing services is their views on the prospects of geriatric nursing services and their attitudes towards the aged. Universities should further strengthen the discipline construction and curriculum reforms of geriatric related majors, pay attention to the education of career prospects, cultivate a positive attitude towards the aged, and increase the willingness of students to engage in geriatric nursing services.

Objective To explore comprehensive nursing measures to the high-risk patients with cerebral apoplexy in nursing outpatient and evaluate the effect.Methods Convenience sampling method was used to select 75 high-risk cerebral apoplexy patients in the nursing outpatient from April 201 4 to December 201 4,patients were carried out comprehensive nursing measures including measuring blood pressure,body weight,and abdominal circumference,instructing to take medication correctly and establish a healthy physical exercise and diet style.Results After 6 months of intervention,systolic blood pressure and diastolic blood pressure of the subjects decreased from (1 48.40 ±1 3.86)mmHg to (1 33.1 ±1 2.49)mmHg and (84.75 ± 8.50)mmHg to (79.75 ±7.40)mmHg respectively(P <0.05).Before and after intervention,the reasonable exercise rate rose from 41 .3% to 72.9%,smoking rate decreased from 53.3% to 21 .4%,compliance with medication rose from 52.0% to 85.7%,salty diet rate decreased from 56.0% to 37.1 %,oiled diet rate decreased from 69.3% to 1 5.7%,compliance with fruit intake rose from 38.7% to 90.0%,compliance with milk drink rose from 30.7% to 75.7%(P <0.05).Conclusions Outpatient comprehensive stoke intervention measures to patients with high-risk for cerebral apoplexy can reduce the risk factors to stoke,improve lifestyle and provide basis for stoke high-risk population.

This case report has described a case of papillary carcinoma of thyroglossal duct in a young male. This patient was admitted with a mass in the anterior neck for 2 years. Preoperative Bultrasonography, CT and MR showed a subcutaneous cystic mass with irregular calcification shadow in the central region of the neck without obvious enhancement. Initial diagnosis was thyroglossal duct cyst, and was excised by Sistrunk under general anesthesia. The postoperative pathological examination showed thyroglossal duct cyst combined with thyroid papillary carcinoma, which was confirmed by immunohistochemistry as thyroglossal duct papillary carcinoma.
Humans ; Male ; Thyroid Neoplasms/surgery* ; Carcinoma, Papillary/pathology* ; Thyroglossal Cyst/surgery* ; Thyroid Cancer, Papillary

ObjectiveBased on the inhibitory activity of phosphodiesterase （PDE）， a method for determining the anti-inflammatory activity of Qingjin Huatantang was established to supplement and improve the quality control system of this famous classical formula. MethodHigh performance liquid chromatography （HPLC） was used to determine the activity of PDE， and the dose-effect relationship of inhibiting PDE activity of Qingjin Huatantang was investigated. The mobile phase consisted of methanol-0.5% acetic acid aqueous solution （5∶95）， and the detection wavelength was 254 nm. By measuring the PDE inhibition rate of multiple batches of Qingjin Huatantang water extract lyophilized powder， biological activity was marked with the activity of the neutralizing enzyme in the international unit U. ResultWhen the concentration of reaction substrate （cyclic adenosine monophosphate） was 50 μmol·L^-1 and the reaction time was 60 min， the enzymatic reaction was stable with 4 U·mL^-1 of PDE. In this reaction system， when the concentration of Qingjin Huatantang water extract lyophilized powder was 0.11-3.0 g·L^-1， the inhibitory effect of PDE showed a concentration-dependent relationship. It was determined that the concentration of Qingjin Huatantang water extract lyophilized powder to be tested was 1 g·L^-1， which showed a significant and stable inhibitory effect on PDE， and the inhibitory rate was >45%， that is， 1 mg of Qingjin Huatantang water extract lyophilized powder could neutralize the activity of 1.8 U PDE at least. ConclusionThis study establishes a biological activity evaluation method of Qingjin Huatantang based on the inhibitory activity of PDE， and the anti-inflammatory activity of Qingjin Huatantang is characterized by international unit U of PDE activity， which can provide a new method for the determination of biological activity of traditional Chinese medicine compounds.