To resolve the problem of methodology of exercise echocardiography andthe criterion and value for evaluating left ventricular (LV) pumping func-tion, 68 healthy persons (age 54.8?8.9 years) and 48 patients with coronary artery disease (age 57.6?5.7 years) were studied by echocardiography bothat rest and during bicycle ergometer exercise in the supine position. Mostsubjects (76.8%) having clear echocardiograms at rest also acquired cleartracing during exercise. Fifty percent of patients had abnormal responsesto exercise. There were no increase in ejection fraction (EF%), percentchanges of diameter (△D%) and stroke volume index (SVI). All these weresensitive indices for determining LV pumping function reserve. Six indicesincluding △D%, PEP/LVET, mVcf at rest, exercise, increment of EF%, △D%and SVI were used as comprehensive assessing criterion of LV pumpingfunction. Compared with the indices of the rest state, the abnormal ratioof LV pumping dysfunction found in patients were raised from 21% to 37%by the indices of the exercise increment and further to 56% by the compre-hensive assessing criterion. This was not in the case of healthy persons.It showed that exercise echocardiography and comprehensive assessing cri-terion might enhance the sensitivity of evaluating LV pumping functionwithout affecting its specificity. It is suggested that they might be adaptedin the research works in rehabilitation medicine and sports medicine.