[Objective] To observe the therapeutic effect of Zhuye Shigao Decoction (ZSD) for the treatment of deep candidiasis in mice. [Methods] One hundred and sixty mice were randomized into immunosuppressive (IS) group and non-immunosuppressive (NIS) group, 80 in each group. The IS mice were given with intraperitoneal injection of cyclophosphamide 200mg/kg and the NIS mice were given with normal saline 0.2mL. Five days later, both groups were vaccinated with Candida albicans solution 0.2 mL through the caudal veins (8 ? 109/L for the NIS mice and 3 ? 109/L for the IS mice). Three hours after vaccination, 20 of the two groups were treated with ZSD 30g/kg, 20 with fluconazole (Img/kg for IS mice and 0.5mg/kg for NIS mice), 20 with ZSD and fluconazole (the medication interval being one hour) and other 20 with same volume of distilled water. The treatment lasted 7 days and the mean survival time and survival colony in the kidney were observed. [Results] ZSD prolonged the survival time (P

Objective To discuss microvessel density (MVD) and expression of vascular endothelial growth factor(VEGF), androgen receptor(AR) in the prostates of men who received re-operation after TURP. Methods Fifty cases were performed re-TURP (re-TURP group) and the remaining 50 cases served as controls. 150 specimens were collected. Sections were stained for CD34 and VEGF, AR by immuno-histo-chemistry(S-P). Statistical analysis of the results was performed using t-test or Pearson Chi-Square test Results The expression of VEGF, AR and MVD were significantly higher in the re-TURP group compared to controls(P<0. 05),but in re-TURP group, difference in VEGF and AR expression as well as MVD were not found to be significantly different between the first and the second TURP(P>0.05). Conclusion Over expression of VEGF and AR as well as high MVD in prostatic tissue might play an important role in the pathological process of BPH after TURP.