Objective To explore the effect of aerobic exercise on cardiac function,heart rate recovery and the quality of life of elderly heart disease patients.Methods One hundred senile heart disease patients were studied.They were randomly divided into a control group and an observation group,with 50 in each group.Both groups were provided with the conventional anti-platelet aggregation treatment,dilation of blood vessels and control of blood pressure.The observation group was also given individualized aerobic exercise training.At the outset and after 3 months the cardiac function and heart rate recovery of both groups were observed,and their quality of life was evaluated using the SF-36 life quality scale.Results After the treatment,the average left ventricular ejection fraction of those in the observation group was significantly better than before the treatment,and significantly better than the average among the controls.The average 6-minute walking test time and average maximum oxygen uptake in the observation group were also significantly better than before the treatment and significantly better than among the controls.The average peak heart rate and HRR1 in the observation group had increased significantly,and significantly more than those of the control group.The average total SF-36 score in the observation group was also significantly higher.Conclusion Individualized aerobic exercise can significantly improve cardiac function and promote heart rate recovery in elderly patients with heart disease,which is of clinical value for improving their quality of life.

BACKGROUND:Acute myocardial infarction with acute onset is dangerous, but the aided diagnosis for hyperacute disease mainly depends on electrocardiogram. The advantages of tissue Doppler strain imaging were utilized to help early diagnosis of acute myocardial infarction.
OBJECTIVE:To observe left ventricular transmural peak radial strain and strain time-to-peak of subendocardiac muscle, midmyocardium and subepicardiac muscle using tissue Doppler strain imaging in dogs before and after acute myocardial infarction, and to assess its mechanical characteristics.
METHODS:A total of 16 Beagle dog models of acute myocardial ischemia were established by ligating left anterior descending coronary artery. The two-dimensional apical short-axis views of the left ventricle in five complete cardiac cycles were acquired and stored in TDI-Q workstation before and after acute myocardial ischemia. Transmural peak radial strain and strain time-to-peak of segment, subendocardiac muscle, midmyocardium and subepicardiac muscle at infarct region and baseline were observed.
RESULTS AND CONCLUSION:Peak radial strains at infarct and subendocardiac muscle, midmyocardium and subepicardiac muscle were decreased compared with the baseline (P<0.05). Peak strain gradient disappeared in each layer of infarct myocardium. Strain time-to-peak of the whole segment and infarct myocardium at different layers was significantly postponed (P<0.05). There was a positive correlation of peak radial strain between subendocardium and segment as wel as between medium and segment at baseline (r=0.617, P<0.01;r=0.556, P<0.01). This relationship disappeared at infarct region (r=0.338, P>0.05;r=0.218, P>0.05). Results indicated that after acute myocardial infarction, peak strain gradient disappeared at different layers at infarct region. Acute myocardial ischemia induces peak radial strain decrease at subendocardium, medium, subepicardium and strain time-to-peak at infarct region was significantly postponed, which reflected abnormal cardiac structure and dysfunction, resulted in uncoordinated cardiac motion and asynchronous heart movement. This may be an important mechanical mechanism triggering heart failure.