1.Isolation and identification of lipoidal constituents in Setaria italica (Ⅱ)
Haitang WANG ; Qingliang SHI ; Weiping YIN
Chinese Traditional and Herbal Drugs 1994;0(12):-
Object To study the lipoidal constituents in Setaria italica (L ) Beauv Methods Individual compounds were isolated by chromatography and their structures elucidated by spectral analysis Results Two lipoidals were further isolated They were identified as glycerol-?, ?-dilinolenate-?′-rhamno-rhamnoside (Ⅰ) and 1-monoolein (Ⅱ) Conclusion The two compounds were obtained from this plant for the first time and compound Ⅰ is a new compound
2.Isolation and identification of lipide from Setaria italica Ⅰ
Haitang WANG ; Qingliang SHI ; Weiping YIN
Chinese Traditional and Herbal Drugs 2001;32(4):291-293
To study the lipoidal constituents of Setaria italica Beauv..Methods The constituents were isolated by chromatography and structurally elucidated on the basis of spectral analysis.Results The three glycerides were isolated as dilinolein (Ⅰ), monolinolenin (Ⅱ),α, β-digalactosyl-α′-linolenic-glyceride (Ⅲ).Conclusion These compounds were obtained from the plant for the first time. Compound Ⅲ is a new glycolipin.
3.Study of hydrodynamic in vitro and animal experiment of a homebred pneumatic pulsatile ventricular assist device
Guoning SHI ; Qingliang CHEN ; Tongyun CHEN ; Jianshi LIU
Tianjin Medical Journal 2015;(7):742-744,745
Objective To study in vitro hydrodynamics of a pneumatic pulsatile ventricular assist device developed ex?clusively by China, and establish an animal model for the detection by the device. Methods The hydromechanics experi?ment was performed on an in vitro test loop using MEDOS-System to drive the ventricular assist device, and lycerl-water so?lution was used as circulating medium. The changes of afterload pressure and the output of the pump were monitored, and the impermeability and stability were also assessed after the experiment. Six adult dogs were used as the experimental animals. The device worked in the left heart assistance mode for 1 hour then the ventricular fibrillation was induced by potassium chloride, and then defibrillated after 5 min while the device remained working. The hemodynamics data were monitored con?secutively during the trial. Results The ventricular assist device worked stably and reliably during the hemodynamic exper?iment. The pump can generate more than 4 L/min flow against the afterload pressure of 100 mmHg. There were no significant changes in heart rate at different time points in experimental dogs after left ventricular assist. Comparison between after auxil?iary immediately and former auxiliary, the diastolic blood pressure of dogs increased 30 mmHg with the ventricular assist, and the diastolic pressure increased 19 mmHg. No obvious fluctuation in blood pressure was found during the auxiliary pro?cess. The diastolic blood pressure stayed at 60 mmHg when the heart was in ventricular fibrillation, and returned to normal after electrical defibrillation. Conclusion The ventricular assist device works stably in vitro test, and the pump can meet the need of adult’s ventricular assist. It is effective and security to dogs in short term. The effects of long-term use need to be future proved.
4.Effect of Ankle-foot Orthosis on Activities of Daily Living and Walking Ability of Patients with Low Lumbar Spinal Cord Injury
Zhixi SHI ; Siwen LIU ; Yatao OUYANG ; Jun WANG ; Qingliang CHEN
Chinese Journal of Rehabilitation Theory and Practice 2007;13(11):1017-1018
Objective To observe the effect of ankle-foot orthosis(AFO)on the activities of daily living(ADL)and walking ability of patients with low lumbar spinal cord injury.Methods29 cases with low lumbar spinal cord injury were trained by systematic rehabilitation.According to patients' condition,static AFO or dynamic AFO were assembled for them.All patients were evaluated with Modified Barthel Index(MBI)and Functional Independence Measure(FIM)before and after training,and the walking distances were also measured.ResultsAfter AFO dressed,the ADL scores of patients increased,especially walking ability increased significantly(P<0.05).Of 29 patients,26 cases had outdoor walking ability,3 cases had domestic walking ability.ConclusionSelecting different kinds of AFO according to condition of individual can help patients with low lumbar spinal cord injury to reconstruct their walking ability and improve ability of self-management.