1.Clinic Observation of Tiepi Fengdou Granule as Adjuvant Treatment in Cancer Patients During Chemotherapy
Journal of Zhejiang Chinese Medical University 2006;0(04):-
[Objective] To evaluate the effect of Tiepi Fengdou Granule(TFG) as adjuvant treatment in cancer patients during chemotherapy.[Methods] Twenty patients were treated with TFG,and then we added up integral calculus of Yin Deficiency symptoms,tested blood routine,hepatic and renal function and subgroup of T-cell and NK cell.[Results] The Yin Deficiency symptoms of 7 cases(35%) were improved significantly,and 13 cases were partly improved(65%).Each integral calculus of Yin Deficiency symptoms was descended.The tested blood routine,hepatic function and subgroup of T-cell and NK cell were changed significantly.[Conclusions] TFG could control the symptoms of Yin Deficiency and improve immune function for cancer chemotherapy patients.
2.EXCISION OF EXTENSIVE EYELID MALIGNANT TUMOR AND PRIMARY PLASTIC SURGERY REPAIP
Medical Journal of Chinese People's Liberation Army 1983;0(02):-
The optimal distance from tumor to incision varied according to the cellular type of the tumor. In each case the cutting edge of the excised tissue was checked with frozen sections for cancer cells. Multiple neighboring skin flaps in full thickness raised from the periosteum were used to cover the large defects (the smallest defect is 25 20mm, the largest one is 75 65mm). The results showed that good cosmetic results were obtained in all cases, visual function was preserved in 35 of the 36 patients, and no recurrence of the tumor was found in 5 years' follow-up. One patient with squamous cell carcinoma that disseminated to nasal cavity and sinuses had a complication of meningitis after the operation,and it was cured with proper treatment.
3.Focusing on the application of functional imaging examination in the field of neuro-ophthalmological
Chinese Journal of Ocular Fundus Diseases 2010;26(4):306-309
Functional imaging is a newly arisen interdisciplinary subject compared with the routine radiology displaying anatomy and morphology of lesions. It can exhibit the function-changed information, such as blood flow and metabolism of organs and tissues as visual images or data to provide organizational functions and metabolic information, which makes early diagnosis, more accurate orientation, qualitative definition, and also the prognosis judgment. The ophthalmologists should pay more attention to the functional imaging applications in the field of neuro-ophthalmology.
4.Prognosis for Monochorionic Twins with Twin Reversed Arterial Perfusion Sequence
Qinghua CHEN ; Huajuan CHEN ; Ruan PENG
Journal of Sun Yat-sen University(Medical Sciences) 2017;38(3):386-389
[Objective] The purpose of this study was to evaluate the association of ultrasound findings and different treatments with the prognosis of the pump twin in twin reversed arterial perfusion sequence (TRAP).[Methods] The 55 cases that were diagnosed as TRAP during the period from January 4th 2010 and August 31st 2015 were included.Ultrasound appearances of monochorionic twins were documented in detail when the twins were diagnosed with TRAP initially.At the initial evaluation,presence or absence of the following abnormalities were documented,including the ratio of the acardiac twin to the weight of the pump twin,hydrops fetalis in the pump twin,cardiomegaly in the pump twin,polyhydramnios in the pump twin,oligohydramnios in the acardiac twin and different treatments.The relationship between these ultrasound characteristics and different treatments with mortality of pump twin were analyzed with logistic regression.[Results] A total of 55 cases with TRAP were diagnosed in our institution and three cases were lost to follow up.Selective reduction was performed in 21 cases,termination of pregnancies in 13 and expectant management in 18.Excluding the cases that underwent termination of pregnancy,the remaining 39 cases were divided into two groups according treatment,expectant management group (n=18) and selective reduction group (n=21).Overall survival rate of the pump twin in these two groups was 66.7% and 71.4%,respectively,P =0.748.The markers of perinatal outcome were not significantly different between expectant management group and selective reduction group.Logistic regression demonstrated that cardiomegaly in the pump twin (OR=21.73,95%CI:1.15 ~ 203.89,P < 0.001) were significant correlated with mortality of the pump twin.[Conclusion] The prognosis markers were not significantly different between conservative management and selective reduction group.Cardiomegaly in the pump twin should be considered as risk predictors for mortality of the pump twin in TRAP.
5.OBSERVATION OF BLOOD SUPPLY OF METATARSUSES AND PHALANGEALS IN FETUSES AND INFANTS
Zhigang CHEN ; Qi GUO ; Qinghua MA
Journal of Xi'an Jiaotong University(Medical Sciences) 1981;0(03):-
The blood supply of metatarsuses and pha-langeals in 30 cases of fetuses and infants was ob-served by microangiographic methods. The resultsdemonstrated that diaphyses and cartilages of bothends of metatarsuses and phalangeals gradually in-creased in the fetal period and appeared nourishingartery and cartilage canal. Both ends of metatar-suses and phalangeals gradually decrea.ed in the. infant period and cartilage canals gradually disap-peared also. These implied that the appearance ofcartilage canals was related to the size of cartilageblocks. Cartilage Canals were temporary bloodsystem of fetal cartilage. Characteristics of bloodsupply of metatarsuses and phalangeals: 1. Asym-metrical distribution of blood supply on metatar-suses and phalangeal, that is the blood supply ofepiphyseal end is richer than one of non--epiphy-seal end, is adapted with the difference of growthability at both ends. 2. There is distribution ofcartilage canals at the epiphyseal end of the distalphalanx, and it is adapted with having growth a-bility at the proximal end. These show that bloodsupply of metatarsuses and phalangeals is closelyrelated to their growth and development.
6.Application study of high-sensitivity C-reactive protein and serum lipids detection in type 2 diabetes mellitus
Zhongyu CHEN ; Qinghua YANG ; Jing ZHANG
International Journal of Laboratory Medicine 2006;0(02):-
Objective To discuss the application of serum hs-CRP and lipids detection and the correlations between them in type 2 diabetes mellitus.Methods The levels of serum hs-CRP,TC,TG, HDL-C,LDL-C,ApoA1,ApoB were all measured in 49 type 2 diabetic patients and 53 normal cases.Results The type 2 diabetic group had significantly higher hs-CRP, TC,TG, LDL-C, ApoB and lower HDL-C than the control group. The concentration of serum hs-CRP correlated positively with TG,ApoB and negatively with HDL-C.Conclusion Serum hs-CRP level is associated with serum lipid level and inflammatory response might play an important role in the pathogenesis of type 2 diabetes mellitus. In type 2 diabetic mellitus there is an increased risk of development of cardiovascular diseases.
7.Clinical application of polynomial fitting curve
Zhongyu CHEN ; Qinghua YANG ; Hongfei XIE
International Journal of Laboratory Medicine 2006;0(05):-
Objective To discuss the clinical application of polynomial curves fitting.Methods Based on the experiments of TBIL, ALT, DBIL and Cr,the linear experimental data were polynomial fitted.Results The optimal polynomial of TBIL is y=-3.886+7.544x , and the evaluation is linear 1; The optimal polynomial of ALT is y=5.293+25.897x-0.043 x~2, and the evaluation is linear 2;The optimal polynomial of DBIL is y=-2.950+1.688x+0.011x~2, and it′s non-linear; The optimum polynomial of Cr is y=11.654+14.512x-0.010 x~2, and the evaluation is inexactitude.Conclusion The polynomial fitting curve is the perfect linear evaluation method. It guarantees both the accuracy and reliability of the experimental results, and is more suitable to clinic.
8.Studies on the correlation between ischemic disease of lower extremity and coronary artery disease and stroke
Yuya ZHANG ; Qinghua WU ; Zhong CHEN
Medical Journal of Chinese People's Liberation Army 2001;0(12):-
Objective The purpose of the study was to investigate the correlation in incidence and severity between peripheral arterial disease(PAD) and coronary artery disease and stroke in Chinese people,in order to assess the essentiality of Ankle Brachial Index(ABI) examination for all the patients.Methods Patients hospitalized to Departments of Cardiology,Neurology and Vascular Diseases from March 2006 to December 2007 were enrolled.ABI was measured,and the disease history was collected.Ejection fraction(EF),coronary arteriography and ultrasound examination of the cervical artery were recorded to analyze the relationship between them and ABI.The prevalence of decreased ABI was calculated.Results In 132 patients hospitalized in the Department of Cardiology,the prevalence of ABI
9.Treatment of Takayasu's arteritis with thoracoabdominal aorta stenosis by percutaneous transluminal angioplasty(PTA)
Qinghua WU ; Lei KOU ; Zhong CHEN
Chinese Journal of Minimally Invasive Surgery 2001;0(06):-
Objective To summarize our experience in percutaneous transluminal angioplasty(PTA) in the management of thoracoabdominal aortic stenosis of Takayasu's arteritis. Methods From 1987~2001, 12 patients of Takayasu's arteritis with thoracoabdominal aortic stenosis underwent PTA. Aortography and pressure of stenotic segment of arota before and after angioplasty were used to evaluate efficacy. Color Doppler ultrasound examination and Doppler segmental pressure measurement were used in follow-up. Results Success was achieved in all cases without mortality and serious complications except for 1 case of acute thrombosis of iliofemoral artery. The residual stenosis were less than 50% in all cases and the pressure gradient was 5 0mmHg~10 5 mmHg with average pressure being 7 2 mmHg after angioplasty ,although they were 25mmHg~46 mmHg averaging of 37 7 mmHg before angioplasty. All cases were followed up for 9(12~72) months and the result was good without lumen restenosis and obstruction. Conclusions PTA is the first choice for Takayasu's arteritis of thoracoabdominal aortic stenosis of local size and proved to be safe, effectiveand economical. It is also effective for long size cases. It is not necessary to dilate aorta stenosis to normal size, and reducing pressure gradient effectively is enough.
10.The Effects of Different CO2 Pneumoperitoneum Pressures on Laparoscopic Cholecystectomy under Epidural Anesthesia: A Prospective Randomized Controlled Trial
Qinghua YIN ; Yajin CHEN ; Lei ZHANG
Chinese Journal of Minimally Invasive Surgery 2005;0(09):-
0.05).Conclusions Epidural anesthesia and lower pneumoperitoneum pressure(8 mm Hg) can completely meet with demands of most LC operations,and have the advantages of safety,economy and minimal invasion.