1.The relationship between the coping style and serf-concept of college engineering students
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(11):1029-1030
Objective To study the relationship between the coping style and self-concept of college engi-neering students.Methods 559 engineering students were assessed with the Coping Style Questionnaire and the Tennessee Serf-Concept Scale.Results (1) The positive factors of self-concept had significantly negative correla-tion to the coping styles of serf-blame,illusion,avoidance,and rationalization(-0.445~-0.136,P<0.01),but had significantly positive correlation to the coping style of solving problem and seeking help(0.119~0.432,P<0.01).Serf-criticism had significantly negative correlation to the coping styles of serf-blame,illusion,avoidance,and rationalization(0.134~0.215,P<0.01);(2)There were significant differences between high self-concept students and low self-concept students for coping styles(P<0.01) ;(3) The factors of serf-concept had significant predictability on coping styles.Conclusion There was a higher correlation between the coping style and serf-con-cept of college engineering students.
2.Research progress of decoy receptor 3 in cancer
Cancer Research and Clinic 2012;24(5):354-357
Decoy receptor 3(DcR3) gene expresses highly in some malignant tumors,it involves cellular proliferation regulation, inhibition of apoptosis, immune escape and tumor angiogenesis by competitively blocking the Fas/FasL, LIGHT and TL1 A/DR3 signal pathway, therefore it deeply relates to the malignant tumors's generation and progression.DcR3 is supposed to be the new tumor-specific marker that may cast the light to the tumor generation,development,prevention,diagnosis,treatment,prognosis and effect observation.DcR3 is expected to be open a new chapter in clinical application.
3.Observation of curative effect of budesonide combined with terbutaline aerosol inhalation in the treatment of acute asthma
Chinese Journal of Primary Medicine and Pharmacy 2017;24(10):1567-1570
Objective To investigate the efficacy of budesonide combined with terbutaline atomization inhalation in the treatment of acute asthma attacks, and to provide reference for clinical treatment.Methods 118 patients with acute asthma attack were selected and randomly divided into observation group and control group, 59 cases in each group.The control group was treated with budesonide inhalation, the observation group was treated with budesonide combined with terbutaline aerosol inhalation The clinical efficacy of the two groups, clinical symptoms and signs of the disappearance time were compared, the pulmonary function test results and the occurrence of adverse reactions were compared.Results In the observation group,the total effective rate was 72.88%, which was significantly higher than 52.54% of the control group (x2=5.218,P<0.05).The disappear time of shortness breath, cough, pulmonary rales in the observation group were (4.01±1.42)d, (6.58±1.51)d, (7.02±227)d, which were significantly shorter than (5.71±1.59)d,(8.52±1.97)d,(8.69±2.61)d in the control group (t=4.557,4.421,4.659,all P<0.05).After treatment, the FEV1,FVC and peak expiratory flow (PEF) of the observation group were (2.35±0.67)L, (2.76±0.62)L, (2.91±0.49)L, which were significantly higher than(2.09±0.57)L,(2.31±0.51)L,(2.48±0.59)L of the control group (t=3.625,3.641,3.887,all P<0.05).The two groups had no serious adverse reactions.Conclusion Budesonide combined with terbutaline atomization inhalation can relieve the clinical symptoms of patients with acute asthma,improve lung function,improve the clinical treatment effect and has good security.
4.Effect of PDCA Cycle on Infection Control in Male Psychiatric Closed Wards
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To investigate whether PDCA(plan-Do-check-action) cycle could lower the incidence of the nosocomial infection in the male psychiatric closed wards.METHODS Data were collected both prospectively and retrospectively.PDCA cycle was used to manage infection control in the male psychiatric closed wards in 2006;whereas the usual method used in the infection control in 2005 was treated as a control group.RESULTS The incidence of the nosocomial infection lowered from 9.94% in 2005 to 5.57% in 2006(P
5.Applications of digital department in otolaryngology.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(7):501-504
OBJECTIVE:
The aim of this study is to explore the applications of digital department in otolaryngology concern with the emergent and dangerous of otolaryngology diseases.
METHOD:
We have constructed digital otolaryngology head and neck surgery department on the basis of hospital information system, which is constructed under the guidance of the theories and methods of modern information integration technology, computer software technology, health informatics and network information technology.
RESULT:
The foundation of digital otolaryngology department can optimize digital workflow, improve work efficiency and eliminate the manual operation.
CONCLUSION
Digital department in otolaryngology will promote the quality and upgrade the level of medical staff, it plays an important role in the hospital informationization.
Hospital Information Systems
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Otolaryngology
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Software Design
6.The influences of paroxetine modified Xiaoyao pill therapy on subjective well-beingfor type 2 diabetes patients with anxiety
Zhiyu WANG ; Qingfeng MA ; Zhihui CHEN
International Journal of Traditional Chinese Medicine 2012;34(8):689-691
Objective To explore the influence of integrated Chinese and western medicine therapy on anxiety,sugar metabolism and subjective well-being for type 2 diabetes Patients associated with anxiety.Methods Use glycated hemoglobin (HbAlc),trait anxiety inventory(TAI),and Memorial University of Newfoundland Scale of Happiness (MUNSH) to evaluate the condition of 60 patients with type 2 diabetes associated with anxiety.The patients participated in the study were randomly divided into Western medicine therapy group(control group)and integrated traditional Chinese and Western medicine therapy group (experimental group),with 30 cases in each group.The control group was treated with paroxetine while the experimental group was treated with paroxetine plus Jiawei-Xiaoyaowan.6 weeks after treatment,we tested the HbAlc level.TAI score and MUNSH score of those patients.Results After 6 weeks,the TAI score of patients in both experimental group and control group have obviously decreased (before treatment:54.07±6.41 and 56.33 ±6.01,respectively; after treatment:38.89±6.70 and 45.29±6.55,respectively) and the difference was statistically significant (P<0.05).And the TAI score of the two groups after treatment was significantly different (P<0.05).For both experimental and control groups,the HbA1e level were not obviously changed before and after the study with P>0.05 (before treatment:8.14±2.69 and 8.07±2.11,respectively; after treatment:8.21±2.07 and 7.92± 1.90,respectively).Comparison between groups also showed no significant difference.MUNSH score have obviously increased in experimental group (before treatment:40.49±5.22; after treatment:44.53 ± 6.28,P<0.05).The result of comparison between the two groups after treatment shows that MUNSH score of patients in the experimental group were obviously improved compared with patients in the control group (57.56 ±6.39),and the difference was statistically significant (P<0.05).Conclusion The integrated traditional Chinese and western medicine therapy can obviously release anxiety and enhance subjective well-being in patients with cerebral infarction associated with anxiety.
7.Clinical analysis of stenting administration on angioplasty of patients with vertebrobasilar artery stenos
Qingfeng ZHU ; Shide CUI ; Guofang WANG
Clinical Medicine of China 2014;30(4):367-369
Objective To investigate the long-term effect of angioplasty of patients with symptomatic vertebrobasilar artery stent.Methods Thirty-three patients with symptomatic vertebral artery stenosis who underwent endovascular treatment stent.The clinical symptoms and stent restenosis were recorded.Results The clinical symptoms of 33 cases with angioplasty were improved significantly.The preoperative stenosis rate was (92.36 ±3.23)% before operation and the average postoperative residual stenosis rate was (9.13 ±2.57)% after operation.Clinical symptoms of 23 patients disappeared completely after operation,and 10 cases improved significantly.As to complications,1 case with severe basilar artery stenosis had a side numbness of extremities,1 case showed postoperative cerebral embolism,and return to normal after 3 days.When follow up periods lasted for 6-24 months,9 cases were with dizziness or other symptoms.Of which,29 cases were performed DSA imaging,the residual stenosis rate was (19.27 ± 5.62)%,3 cases of vertebral artery in-stent restenosis were reached over 50%.Those 3 cases were give stent angioplasty again and the uncomfortable symptoms disappeared.Conclusion Stenosis opeation can significantly alleviate the symptoms of cerebral ischemia and symptomatic vertebrobasilar artery,and improve the quality of life of patients.However,restenosis should paid more attention.
8.The clinical effect and safety of endovascular stenting in treatment of upra-arch extra intracranial artery stenosis
Qingfeng ZHU ; Guofang WANG ; Yanlong DU
Chinese Journal of Postgraduates of Medicine 2013;36(35):29-33
Objective To discuss the operative methods,clinical effect and safety of endovascular stenting in treatment of upra-arch extra intracranial artery stenosis.Methods Symptomatic carotid artery stenosis > 50%,or no symptomatic stenosis > 75% with upra-arch extra intracranial artery stenosis patients were treated by endovascular stenting,of all patients,85 cases with carotid artery stenosis,37 cases with vertebral artery stenosis,6 cases with subclavian artery stenosis.Results One hundred and twenty-eight patients were treated with 130 vessel,used 131 stents,59 patients used vascular protection,the achievement rate of stent implantation was 100.00%.The degree of stenosis were significantly improved,the degree of stenosis from (87.65 ± 8.70)% to (14.28 ± 4.87)%.Twenty-six patients appeared transient decline in blood pressure and heart rate,31 patients appeared persistent hypotension and decrease in heart rate.One patient (no using of vascular protection) appeared obhteration in ipsilateral middle cerebral artery,the artery was recanalization after thrombolysis treatment.The rest of 127 patients did not appear intraoperative vascular embolization complications.Eighteen patients appeared perioperative perfusion in transition,1 case happened cerebral hemorrhage (< 10 ml).Postoperative symptoms were improved significantly.Followed up for 6-36 months,84 patients had not restenosis in stent,1 patient had symptomless restenosis (< 50%).In 37 patients with vertebral artery stenosis,3 patients again appeared ischemia symptoms in postoperative 1 year,digital subtraction angiography (DSA) showed restenosis in stent,the patient was again given endovascular stenting,the symptoms disappeared.Conclusion As long as the correct choice of indications and perioperative treatment properly,the endovascular stenting in treatment of upra-arch extra intracranial artery stenosis has good clinical effect and high security.
9.Comparative genomic hybridization technique detects the chromosomal aberration in renal carcinoma
Jian WANG ; Renfang XU ; Qingfeng SONG
Basic & Clinical Medicine 2010;30(4):398-400
Objective To detect the chromosomal aberration in the cells of renal carcinoma and to evaluate the rela-tionship between the chromosomal aberration and development of renal carcinoma.Methods CGH technology was used to analyze the global genomic aberration in cancer cells from 12 patients with renal carcinoma.Results All of 12 cases deeeted by CGH showed chromosomal aberrations.The common extension regions of renal carcinoma were 1p,4p,5q,7p,9p and 16p.The common deletion regions of renal carcinoma were 3q,4q,6q,9q,14q and 18q.Conclusion The hereditary material of renal carcinoma is unbalanced.The extension and/or deletion of chro-mosome may facilitate the occurrence of renal carcinoma.
10.Polysaccharide from eggs of S. nudus (SEP) prevents cardiomyocyte hypertrophy induced by high glucose and high insulin in vitro in neonatal rat
Qingfeng ZHOU ; Chunhui LIU ; Hongxin WANG
Chinese Pharmacological Bulletin 2015;(6):844-847
Aim To study the protective effects of SEP on the hypertrophic myocardial cells induced with high glucose and high insulin and the mechanism. Methods The protein content was assayed with Lowrys meth-od;the cardiomyocytes area was measured by computer photograph analysis system;the expression of ANF and PPAR-α was determined by RT-PCR;APS was select-ed as control drug. Results Compared with conctrol group,the protein content,cardiomyocytes area and the expression of ANF and PPAR-α of high glucose and high insulin group were significantly increased. Com-pared with conctrol group,the SEP of different dosages were able to decrease the protein content, area, the expression of ANF mRNA and PPAR-α mRNA of cul-tured hypertrophic myocadial cells induced with high glucose and high insulin. Conclusion SEP can pre-vent cardiomyocyte hypertrophy induced by high glu-cose and high insulin, which is related to its inhibition on PPAR-α signaling path.