1.Research on virtual hand control system based on wireless data glove
China Medical Equipment 2015;(12):35-37
Objective:To establish a rehabilitation training system based on virtual hand model, in order to make up the lack of traditional rehabilitation by using vision feedback mechanism of virtual reality, and help patients raise participation enthusiasm and rehabilitation effect through the process of attempt-exercise-correction.Methods: Flex-sensor was used to collect the angle of fingers’ bending. The AD collection module was used to transform the signal to digital and transmitted by serial port.Then the data was transmitted to computer by bluetooth module and used to control the virtual hand.Results: Hall current sensor was accurate and effective for data collection. The acquisition terminal and monitor server were fast and convenient for data transmission and management.Conclusion: A control system for virtual hand based on wireless data glove was constructed, and it could be used effectively for the recovery of hand movement.
2.Study on quality standard of Liancao Oral Liquid
International Journal of Traditional Chinese Medicine 2010;32(2):171-172
Objective To establish the quality standard of Liancao Oral Liquid. Methods The content of scutellarin and p-Coumaric acid in Liancao Oral Liquid was determined by HPLC. Results There was a good linearity for scutellarin in the range of0.208~1.042 μg (r=0.9999) (n=5) , The average recovery rate was 100.3%, RSD=0.81% (n =6) ; There was a good linearity for p-Coumaric acid in the range of 0.079~0.394 μg (r=0.9994) (n=5) , The average recovery rate was 99.6%, RSD=0.94% (n=6) . Conclusion To develop a method of determining the content of Liancao Oral Liquid. The methods are simple, effective with good reproducibility, which can be used for the quality control of Liancao Oral Liquid.
3.Survival status and analysis of related factors of mortality among elderly patients with first-ever stroke
Chongqing Medicine 2015;(26):3647-3648,3651
Objective To describe the survival status and to analyze the related factors of mortality among elderly patients with first-ever stroke.Methods Totally 1 96 elderly patients with first-ever stroke from January 2010 to January 2014 were enroll for the study.The survival status of all cases was attained through follow-up,and the deadline of follow-up was July 30,2014.The deceased patients because of stroke were divided into death group while the others were divided into survival group.Univariate com-parison and multivariate Logistic regression analysis were performed to screen out the related factors of death.Results The median follow-up time was 41 months,and 14 cases were lost to follow-up.The survival rate 28 d,1 year and 3 years after the onset were 73.47%,66.81% and 58.89%.Age,complication,Glasgow score,NIHSS score and blood WBC were the independent influence fac-tors of death (P <0.05).Conclusion The death among elderly patients with first-ever stroke are more concentrated in 28 d after the onset.Advanced age,complications,decrease of Glasgow score,increase of NIHSS score and blood WBC could increase the death risk.
5.Construction of integrated finance management in the military hospital
Xinli YANG ; Qingbo ZHANG ; Heping WANG
Journal of Medical Postgraduates 2003;0(09):-
With the development of paid medical service in military hospitals,finance management is playing a more and more important role in their scientific and capacity development.It is involved in every aspect of hospital management,particularly in the patient-centered medical service.The present study aimed to establish an integral mode of finance management in military hospitals,that is,to combine medical,economic and logistic management into a whole based on finance management,so as to the improve the efficiency of medical resources,raise the hospital's competitive capacity,and promote its social benefits.
6.The detection of serum soluble B7-H4 levels in non-small cell lung cancer patients and its significance
Chunhua XU ; Like YU ; Qingbo WANG
Chinese Journal of Laboratory Medicine 2012;35(7):604-606
ObjectiveTo detect serum soluble B7-H4 (sB7-H4) levels in patients with non-small cell lung cancer ( NSCLC ) and explore its clinical significances.MethodsThe sB7-H4 levels the sera of in 102 NSCLC patients,60 benign lung disease patients and 90 healthy controls were determined by ELISA.The relation between serum sB7-H4 levels and NSCLC of pathological staging was analyzed by use of t test.ResultsThe serum sB7-H4 levels in NSCLC,benign lung disease and heathy control groups were (45.61 ±5.67 ),( 30.14 ± 3.51 ) and ( 28.52 ± 4.76 ) μg/L,respectively.The levels of NSCLC group were significantly higher than those of benign lung disease and healthy control groups ( t =2,59 and 3.61,P < 0.05 ).The serum sB7-H4 levels of Ⅲ/IV stage NSCLC patients ( 63.93 t 4.76 ) μgL,with lymph node metastasis (61.73 ±3.97) μg/L and before operation patients (63.29 ±6.19) μg/L were relatively higher thanthose inthe Ⅰ/Ⅱ stage(35.12 ± 3.88 )μg/L, without lymphnode metastasis (40.26 ± 5.39 ) μg/L,after operation ( 40.51± 4.08 ) μg/L.There were significant difference ( t =6.78,5.73 and 3.67,P < 0.05 ).Conclusions Serum sB7-H4 of NSCLC patients increases significantly and correlates with clinical stages and therapeutic conditions.Detecting on sB7-H4 is helpful for lung cancer diagnosis and therapeutic effect evaluation.
7.HPLC Simultaneous Determination of Sodium Danshensu, Hesperidin and Salvianolic ;Acid B in Niaosaitong Capsules
Shaoqing WANG ; Xing JIN ; Qingbo ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2014;(6):83-85
Objectives To establish an HPLC method for determination of sodium Danshensu, hesperidin and salvianolic acid B in Niaosaitong capsules. Methods Three components were separated by C18 chromatographic column with a gradient mobile phase consisting of acetonitrile and 0.1%phosphoric acid solution at a flow rate of 1.0 mL/min, column temperature of 30 ℃, and detection wavelength was set at 286 nm. Results Sodium Danshensu, hesperidin and salvianolic acid B had good linearity in the range of 0.038 44-1.922 μg, 0.000 207 052 8-4.044 μg, 0.034 28-1.714 μg respectively, and the average recovery rate was 90.9%-107.1%, RSD was 2.1%-3.2%. Conclusion The methods is simple and accurate, and can be used for the quality control of Niaosaitong capsules.
8.The levels and clinical significance of osteopontin in serum of patients with lung cancer
Chunhua XU ; Like YU ; Qingbo WANG
Journal of Chinese Physician 2012;14(2):179-181
ObjectiveTo explore the levels and clinical significance of osteopontin (OPN) in serum of patients with non-small cell lung cancer (NSCLC).MethodsOPN levels of 102 cases of NSCLC,42 cases of benign lung disease and 30 cases of healthy control were measured by enzyme-linked immunosorbent assay(ELISA).ResultsThe serum OPN levels of NSCLC were significantly higher than those of benign lung disease group and healthy control group (P<0.01).The levels of OPN in serum were compared between different gender,age,histological differentiation and pathological type groups,but there were no significant difference (P>0.05).The serum OPN levels of Ⅲ - Ⅳ stage NSCLC patients,with lymph node metastasis,before operation patients,recrudescent patients,survival below 3 years patients were relatively higher than that in the patients with Ⅰ - Ⅱ stage,without lymph node metastasis,after operation,no recrudescent,survival over 3 years patients,and the differences were significant (P<0.01).ConclusionsOPN levels in serum reflected the severity of the disease,which can be used to determine the effects of surgery and monitor recurrence and evaluate prognosis.
9.Clinical efficacy Comparison between laparoscopy and open cholecystectomy for acute calculous cholecys-titis
Zhiqiang WU ; Weidong WANG ; Qingbo LIU
The Journal of Practical Medicine 2017;33(13):2173-2175
Objective To compare the clinical efficacy between laparoscopy and open cholecystectomy for patients of acute calculous cholecystitis. Methods Fifty patients of acute cholecystitis from February 2014 to February 2017 were divided into control group treated with open cholecystectomy and observation group with laparoscopic cholecystectomy;a retrospective analysis was conducted to compare time of resuming peristaltic sound ,postoperative 24h VAS score and hospitalization time. Results There were shorter time of resuming peristaltic sound,higher postoperative 24 h VAS score and shorter hospitalization time in observation group when compared with those in control group (P < 0.05). Conclusions For patients of acute calculous cholecystitis , laparoscopic cholecystectomy,is conducive to shortening patient′s recovery time,alleviating patients′ pain signifi-cantly and decreasing the incidence of complication.
10.Effect of stress level on blood coagulation and fracture healing in fracture patients
Zhengqiang CAI ; Lanlin PENG ; Zheng CHEN ; Qingbo WANG ; Zhongmou ZHENG
Chinese Journal of Orthopaedic Trauma 2017;19(4):353-356
Objective To investigate the effect of stress level on blood coagulation and fracture healing in fracture patients.Methods The clinical data of 50 fracture patients (fracture group) and 50 healthy volunteers (control group) were analyzed retrospectively.The oxidative stress indexes [superoxide dismutase (SOD) and malondialdehyde (MDA)] and blood coagulation indexes [plasma fibrinogen (Fib),activated partial thromboplastin time (APTT),thronbin time (TT),and prothrombin time (PT)] were compared between the 2 groups.Correlation between stress level and coagulation indexes in the fracture patients was analyzed by Spearman correlation coefficient.The correlation between stress level and the progress of fracture healing in fracture patients was analyzed.Results There were no significant differences in APTT,TT,PT or other blood coagulation indexes between the 2 groups (P > 0.05).The fracture group had a significantly lower SOD level but significantly higher MDA and Fib levels than the control group (P < 0.05).Spearman analysis showed that the SOD level was negatively correlated to the Fib level (P < 0.05) while the MDA level was positively correlated to the Fib level in the fracture group (P < 0.05).The MDA level was negatively correlated to the process of fracture healing (P < 0.05) while the SOD level was positively correlated to the process of fracture healing in the fracture group (P < 0.05).Conclusions Traumatic fracture can cause stress reaction.It should be kept in mind that the severity of stress reaction is closely related to the Fib level and the process of fracture healing.