Medical ethics has its own characteristics on curriculum setup,teaching goals,the structure of teaching staff in America,France and China,It is beneficial for our feform in education in medical ethics to learn and refer to the experiencs of the success abroad.

Animals ; Cerebral Cortex ; cytology ; physiology ; Delayed Rectifier Potassium Channels ; physiology ; Neurons ; physiology ; Patch-Clamp Techniques ; Rats ; Rats, Sprague-Dawley

The rational design of teaching contents of physical pharmacy plays an important role in the class teaching.Some practices of designing teaching contents are expounded in detail,including the combination with teaching cases,the integration of the teaching contents,the combination with the research results of the physical pharmacy,and the combination with the pharmaceutical experiments of traditional Chinese medicine.The innovation of this research is the combination of theory and practice and the infiltration between teaching and scientific research.It also puts forward some measures such as continually accumulating and improving the related material,and constructing a rich,shared source material storehouse,etc..

Angioplasty, Balloon, Coronary ; methods ; Coronary Artery Bypass ; methods ; Coronary Vessels ; surgery ; Humans

Thyroid carcinoma is one of the most common diseases in the head and neck area. With the advance of innovative technologies like ultrasound ,fine-needle aspiration and PET-CT, the number of patients diagnosed as thyroid carcinoma has grow rapidly during the past ten years. As a special structure in papillary tumors and appearing as microcalcification in the imaging examination, psammoma body has been considered of great significance in the diagnosis of thyroid carcinoma. Psammoma body has unique features in terms of pathology, cytology and imageology.The study of the mechanism of psammoma body formation is very important for the clinic to differentiate the disease from others. In this article, we summarized the role of psammoma body in the study of thyroid cancer.

Objective To investigate the status of urogenital Ureaplasma urealyticum (Uu) infection and their drug tolerance in our area,so as to guide rational administration for the clinic.Methods Mycoplasma culture and drug susceptibility test were performed for 771 patients with urogenital infaction. The culture,identification and drug resistance of mycoplasma were carried out with one complex mycoplasma kit.Results The positive rate of Uu was 49.9%. The proportional percentage of males was 12.5% and the Uu positive rate was 22.3%,for females,the proportional percentage and Uu positive rate was 87.5% and 60.6% respectively. The population aged 21-40 was susceptible to Uu infection. The most sensitive antibioties to Uu was clindamycin (95.12%),followed by doxycycline (87.57%) and roxithromycin (86.24%).Conclusion The difference of Uu drug sensitivty was significant in different areas. So it is necessary to select antibioties by drug sensitivity. Clindamycin,doxycycline and roxithromycin may are used as preferred antibioties in treating Uu infection in our area. The drug-resistance status of spectinomycin and lincomycin was serious.

Objective To investigate the effects of different technical conditions on the microvesicle size,envelopment rate,morphology of surface and so on in order to select the best technical conditions to prepare HCPT(10-hydroxy-camptothecin)-loaded PLGA microvesicles.Methods Microvesicles were prepared by a water/oil/water emulsion and solvent evaporation method.Various factors related to the envelopment rate and micmparticle size were studied,such as the ratio of water phase and oil phase,ultrasound power,and time,stirring time and so on.Single factor experiments and orthogonal design testing was carried out to optimize the technology of microvesicles preparation.Results The best processing conditions for microvesicles preparation were as following: HCPT 25 mg,PLGA 1.875 g,the ratio of internal and external phases 1∶15,and the PVA concentration 3%.These preparative variables produced global,smooth and glossy microvesicles.Electric charges were probably between-40 to 0 mV,microvesicles sizes ranged from 500 to 1 000 nm,envelopment rate was 79.33%,drug loading to the microvesicles was 0.478 3%,and ultrasonic imaging was clear in vitro.Conclusion Our optimize technical conditions can prepare injectable microvesicles by ultrasound.

During cell apoptosis,a series of characteristic changes occur in the cell configuration and,according to recent findings,in the cytoskeleton as well,including degradation,condensing and maldistribution of the cytoskeleton reticular formation.Through investigations of the biological activity and function of the cytoskeleton protein,the dynamic changes of the cytoskeleton during cell apoptosis and related regulatory factors,we found that the change of configuration is based on that of the cytoskeleton during cell apoptosis,which suggests that we can achieve the purpose of curing tumors and other diseases by inducing cell apoptosis through changing the cytoskeleton configuration.

There are many kinds of scaffolds used in the field of tissue engineering, which can be divided into natural biological scaffolds and synthetic scaffolds. This paper summarizes the latest advances of research on scaffolds of skin tissue engineering and review amounts of related literatures on this field. The result shows that natural biological scaffolds can provide a better three-dimensional space for the adhesion and generation of cultured cells. These scaffolds have an extensive application in skin tissue engineering.

OBJECTIVE: To explore the working pattern of clinical pharmacists in participating in clinical medicine treatment.METHODS: The working pattern and working contents of clinical pharmacists in participating in clinical medicine treatment were come up with based on hospital pharmacy and the traditional working pattern of pharmacists in China as well as the working pattern of the students in the clinical pharmacist training pilots.RESULTS & CONCLUSION: To participate in clinical medicine treatment,pharmacists should possess certain professional background and have occupational orientation,and attach great importance to the continuing education of clinical pharmacy expertise and medicine-related expertise.