1.Research on five stagnations in seven chapters about five evolutive phases and six climatic factors of Plain Questions
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
Five stagnations are an important content of Plain Questions.Many doctors think highly of the treating principle,while overlook the other content.Through researches on Plain Questions,the author lays out the entire system,including the prevention and treatment for mild stagnation,the presymptom,changes on phenology,climate and human body for severe stagnation.
2.Construction of a predicting model of uncertainty in illness for the postoperative patients with digestive system tumors undergoing chemotherapy
Qing PAN ; Weili WANG ; Jingfang HONG
Chinese Journal of Practical Nursing 2013;(13):1-4
Objective Construction of a predicting model of uncertainty in illness based on Mishel's theories of uncertainty in illness in a sample of the postoperative patients with digestive system tumors undergoing chemotherapy.Methods By convenient sampling method,MUIS-A,MSAS,SSRS were used to evaluate 484 postoperative patients with digestive system cancer during chemotherapy period,and then AMOS 17.0 software was used to perform analysis.Results The score of uncertainty in illness of postoperative patients with the digestive system cancer undergoing chemotherapy was in the medium level (89.86+11.84) points; Structure provider (social support,economic income) could not only reduce the uncertainty directly,but also had an indirect effect on the uncertainty by stimuli frame (symptoms pattern,event familiarity).Conclusions Structure equation model can be applied to the uncertainty in illness model construction,so as to help medical staff manage uncertainty in illness pertinently.
3.Application of Wood's lamp in the diagnosis of superficial cutaneous fungal infections
Qing ZHAI ; Weili PAN ; Jinying LIN
Chinese Journal of Dermatology 2011;44(4):277-278
Objective To estimate the performance of Wood's lamp examination in the diagnosis of superficial cutaneous fungal infections. Methods Totally, 129 patients, who were diagnosed with superficial cutaneous fungal infections according to clinical medical history and signs, were enrolled in this study. Wood's lamp examination of lesions was carried out. Cutaneous samples were obtained from the patients and subjected to microscopic examination and fungal culture. Results Wood's lamp examination was positive in 84% and 85.7% of patients with tinea versicolor and malassezia folliculitis, respectively; among these patients positive for Wood's lamp examination, 92.9% were positive for fungal culture, and 87.5% for microscopic examination. In patients clinically diagnosed with tinea manus and pedis, tinea corporis or tinea cruris, 8.3% were positive for Wood's lamp examination, while 85.4% were positive for fungal examination. There was a high consistency between Wood's lamp examination and fungal examination in patients with tinea versicolor and malassezia folliculitis, but not in those with tinea manus and pedis, tinea corporis or tinea cruris. Conclusions Wood's lamp examination shows a high specificity and sensitivity and is useful in the diagnosis of tinea versicolor and malassezia folliculitis, but seems unapplicable for the diagnosis of tinea manus and pedis, tinea corporis or tinea cruris.
4.Early Mobilization for Intensive Care Unit Acquired Weakness (review)
Shiqin PAN ; Qing ZHANG ; Li WANG
Chinese Journal of Rehabilitation Theory and Practice 2017;23(1):50-53
Early mobilization is beneficial in the prevention of intensive care unit acquired weakness. This paper summarized the meth-ods, opportunity, evaluation of early mobilization intervention, and some notes.
5.The clinical differential diagnostic value of multiple parameters analysis method for anemia of chronic disease in elderly patients
Chinese Journal of Geriatrics 2017;36(1):53-56
Objectives To clarify the differential diagnostic value for iron deficiency anemia (IDA)and anemia of chronic disease(ACD)with analysis method of multiple parameters.Methods The serum concentrations of iron parameters (SI,TIBC,TF,SF and sTfR),inflammatory index(IL-1,IL-6,TNF-β),CRP and hepcidin were detected in patients with IDA and ACD by biochemical method and ELISA respectively.Results In the differential diagnosis of IDA versus ACD,the SF (98.6 versus 6.0,P=0)and sTfR/logSF[(13.1-±-4.4) versus (27.6 ± 16.5),P=0.002] had clinical value for the differential diagnosis.Inflammatory factors level was increased in two groups,only the difference in CRP between IDA and ACD showed a statistical significance.The hepcidin had the clinical value in differential diagnosis for single disease diagnosis of IDA and ACD and for differential diagnosis between IDA and ACD [(144.6 ±-1.9) versus (86.5-±-3.1),P< 0.05].Correlation analysis showed that the sTfR/logSF had a significantly negative correlation with SI(P=0.002),a significantly positive correlation with TIBC and TRF,and no significant correlation with inflammatory factors.The hepcidin had significantly positive correlation with IL-6 and TNF-β,and a significantly negative correlation with SI.The positive correlation was observed between sTfR/logSF and Hepcidin(r=0.376,P=0.005).Conclusions Analysis method of multiple parameters could make a differential diagnosis of ACD in the elderly.
6.Advance in Modified Constraint-induced Movement Therapy for Upper Extremity Function Recovery after Stroke (review)
Qing ZHANG ; Shiqin PAN ; Li WANG
Chinese Journal of Rehabilitation Theory and Practice 2016;22(12):1395-1398
Modified constraint-induced movement therapy (mCIMT), which is modified from constraint-induced movement therapy (CIMT), is used in hemiplegics for rehabilitation. It may be used in the selected patients in certain function and age. mCIMT is more flexible than CIMT, which is mainly consisted of intervention movement, intensity, and the time of training and limitation. mCIMT is also used with other rehabilitation methods. There are various assessment for the evaluation of upper extremity motor function. By using Contract and Mo-tor Activity Log, researchers can better guarantee the curative effect.
7.The application of nutrition support in critical ill patients
Fei XIE ; Qing SONG ; Liang PAN
Medical Journal of Chinese People's Liberation Army 1983;0(05):-
Objective To evaluate the efficiency of nutrition support in critical ill patients. Methods A retrospective analysis was made to the efficiency of the nutrition support applied to 233 critical ill patients PN+EEN→EN+per os→per os was employed as the model of nutrition support, and a nasal feeding pump was used for enteral nutrition. Results During the period of nutrition support, in the 233 patients, 26 dead, the mortality was 11.16%. Early enteral nutrition significantly decrease the mortality in critical ill patients. There existed significant differences in complications in three kinds of enteral nutrition may methods. Conclusion It is feasible to give the critical ill patients, it might help to reduced the mortality in ICU patients.
8.Investigation on B-Learning mode in teaching of burn department
Jiaqi LIU ; Dahai HU ; Qing PAN
Chinese Journal of Primary Medicine and Pharmacy 2015;(16):2414-2416,2417
Objective To investigate the application of B -Learning mode in the teaching of department of burns surgery.Methods 234 students were divided into two parts by digital table method randomly.The experimental group was applied by the means of B -learning mode,while the control group was taught by the traditional way.And the results were evaluated.Results The basic theory scores(75.39 ±12.04)points in the students of experimental group were higher than those of the control group(68.27 ±12.38)points.The practice scores(76.42 ±11.89)points in the students of experimental group were higher than those of the control group(65.36 ±12.05)points.Students'professional knowledge scores(79.92 ±12.85)points in the experimental group were higher than those of the control group(71.56 ±13.01)points.Both percentage and score were higher in the experimental group than in the control group in comprehensive ability.Conclusion Blending learning gives students a potential time,environment and recourse to learn.By integrating learning ability and nursing skills improved,B -learning mode plays an important role in improving the quality of burn department internship.
9. Optimization of the extraction process of triterpenoid acids in seeds of Ligustri lucidi fructus by response surface method
Chinese Pharmaceutical Journal 2015;50(13):1093-1097
OBJECTIVE: To optimize the extraction and purification process of total triterpenoid acid in Ligustri lucidi fructus using response surface method and uniform test. Finally, the content of total triterpenoid acid reached more than 50%. METHODS: The content determination of total triterpenoid acid in Ligustri lucidi fructus was established by HPLC. Use ethanol as extraction solvent and through the single factor investigation about the ethanol concentration, solvent amount, extraction time and extraction times, we determined the number of ethanol extraction. In addition to extraction times, the other three factors were further optimized by response surface method. Then purified by the alcohol extraction-water precipitation method to remove the water-soluble ingredients. Petroleum ether was used to remove the chlorophyll, grease and other small polarity ingredients; using ethanol to remove the alcohol soluble components whose polarity is bigger than fructus ligustri lucidi terpene acids. Design the uniform experiment respectively to determine the amount of petroleum ether, frequency and time, also ethanol concentration and dosage. RESULTS: The content of oleanolic acid and ursolic acid is larger than other compounds in total triterpenoid acid in Ligustri lucidi fructus, and they are isomers. When the results are in the equivalent of oleanolic acid, the optimum extraction process was determined as 80%, 10 times the amount of ethanol, extracting for 2 times, each time 0.5 h. The optimal purification process is 12 times the amount of petroleum ether, purified once, 2 h every time. Then 10 times amount of 60% ethanol to purify for once. CONCLUSION: Optimizing the extraction and purification process of total triterpenoid acid in Ligustri lucidi fructus by using response surface method and uniform experiment is simple, feasible and worth promoting.
10.Effect of Tilting Table Exercise and Shengmaiyin on Orthostatic Hypotension after Spinal Cord Injury in Rabbits
Yu PAN ; Qing-min ZHANG ; Hua GUAN
Chinese Journal of Rehabilitation Theory and Practice 2006;12(7):565-567
ObjectiveTo develop an experimental model of orthostatic hypotension (OH) after spinal cord injury (SCI) in rabbits and investigate the effect of tilting table exercise and Shengmaiyin on it. MethodsRabbit model of OH after SCI were induced by complete transection of spinal cord at the T5 spinal segment and raised to 60° head up tilt (HUT) on a tilting table. Tilting table exercise and Shengmaiyin were applied to different groups for 28 d from 4 days after operation. Systolic blood pressure (SBP) and pulse rate (PR) were observed with non-invasive sphygmobolometer of rabbit 3, 10, 17, 24, 31 d after the operation. Liquid chromatography with electrochemical detection(HPLC-ECD) was used to detect the concentrations of plasma norepinephrine (NE) and epinephrine(E) with horizontal position and HUT 60° on the 31st day. ResultsSBP with HUT 60° in rabbits of combined treatment group was significantly higher than that in rabbits of SCI group on the 24th day after operation,and the drop in SBP from horizontal position to HUT60° was significantly lower than that in rabbits of SCI group. SBP with HUT 60° in rabbits of exercise group and combined treatment group was significantly higher than that in rabbits of SCI group on the 31st day after operation. The drop in SBP from horizontal position to HUT 60° was significantly lower in rabbits of Shengmaiyin group, exercise group and combined treatment group than that in rabbits of SCI group on the 31st day after operation. The concentration of E and NE of SCI group, Shengmaiyin group, exercise group and combined treatment group was lower than that of sham group, but there was no significant difference among these groups. ConclusionThe treatment with tilting table exercise and Shengmaiyin can improve OH after SCI partially in rabbits without involving norepinephrine and epinephrine significantly. The period of treatment can be shorten when both therapies used together.